Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   CG712_RS04405 Genome accession   NZ_CP022547
Coordinates   845742..846473 (+) Length   243 a.a.
NCBI ID   WP_002948869.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain B59671     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 840742..851473
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CG712_RS04380 (CG712_04415) - 841840..843230 (+) 1391 Protein_856 IS3-like element ISSth1b family transposase -
  CG712_RS04385 (CG712_04420) - 843376..843618 (-) 243 WP_096811635.1 Blp family class II bacteriocin -
  CG712_RS10720 (CG712_04425) - 843869..844270 (-) 402 WP_011226490.1 hypothetical protein -
  CG712_RS04400 (CG712_04435) - 845257..845487 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  CG712_RS04405 (CG712_04440) comE/blpR 845742..846473 (+) 732 WP_002948869.1 LytR/AlgR family response regulator transcription factor Regulator
  CG712_RS10255 comD/blpH 847010..847813 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  CG712_RS04415 (CG712_04450) - 847831..847992 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  CG712_RS04420 (CG712_04455) comB 848007..849374 (-) 1368 WP_096811636.1 bacteriocin secretion accessory protein Regulator

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27803.11 Da        Isoelectric Point: 6.9136

>NTDB_id=201614 CG712_RS04405 WP_002948869.1 845742..846473(+) (comE/blpR) [Streptococcus thermophilus strain B59671]
MKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLST
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQVLPVSRMKIGKIAQIVEE
RGR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=201614 CG712_RS04405 WP_002948869.1 845742..846473(+) (comE/blpR) [Streptococcus thermophilus strain B59671]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGAGGCTGTGGCACATGAACTTAAATCCTT
CGGAAAAGATCTATCTTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCAGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATCGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGAAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATGAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCACA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACCCATGCCATCGGTCCTATATCGTCAATACAGATATGATCATCTCTGTCAACAAGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTTCTACCAGTATCCCGTATGAAGATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-119)

LytTr DNA-binding domain (LytTR)

(146-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

35.628

100

0.362