Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   Spy49_0240 Genome accession   CP000829
Coordinates   249622..250383 (+) Length   253 a.a.
NCBI ID   ACI60580.1    Uniprot ID   -
Organism   Streptococcus pyogenes NZ131     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 244622..255383
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Spy49_0237c - 244951..246447 (-) 1497 ACI60577.1 Putative glutamine-binding periplasmic protein -
  Spy49_0238 - 246645..248459 (+) 1815 ACI60578.1 hypothetical protein -
  Spy49_0239 bacA 248637..249476 (+) 840 ACI60579.1 Putative undecaprenol kinase -
  Spy49_0240 mecA 249622..250383 (+) 762 ACI60580.1 Adapter protein mecA Regulator
  Spy49_0241 rgpG 250390..251559 (+) 1170 ACI60581.1 Undecaprenyl-phosphate N-acetylglucosaminyl 1- phosphate transferase -
  Spy49_0242 - 251681..252451 (+) 771 ACI60582.1 Iron-sulfur cluster assembly ATPase protein SufC -
  Spy49_0243 - 252546..253808 (+) 1263 ACI60583.1 Iron-sulfur cluster assembly protein SufD -
  Spy49_0244 - 253839..255065 (+) 1227 ACI60584.1 Cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29051.72 Da        Isoelectric Point: 4.1622

>NTDB_id=20129 Spy49_0240 ACI60580.1 249622..250383(+) (mecA) [Streptococcus pyogenes NZ131]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLML
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=20129 Spy49_0240 ACI60580.1 249622..250383(+) (mecA) [Streptococcus pyogenes NZ131]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAATGGAGTT
GAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGACGAACTCGATCTTCCAGATAATT
TTAAAGATAGTGGTATGCTTAGTTTTCGAGTGACTCCACGCAAGGACCGTCTAGATGTTTTTGTTACCAAATCTGAGATA
AATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAAATGACTCCGGAAGATTTTTTCAAGAGCTT
GGAGCAATCCATGCGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTAGAAAAAATTGAAGAGATAATGGAAGATGTTG
TTGAAGCTACTCTAGCTAATCAGTCTGAGGCGGCTGATCCATCAACTAATCATGAGTCAGAACCTTTAGACTATGTCCAT
TATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCCTCAGAGTT
ATATAAGGGGAGCAACTGCTACCATATGACTATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCGAATGTCATGT
ATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTT
GATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.2

98.814

0.625
  mecA Streptococcus thermophilus LMD-9

56.225

98.419

0.553
  mecA Streptococcus thermophilus LMG 18311

55.422

98.419

0.545
  mecA Streptococcus pneumoniae Rx1

48.235

100

0.486
  mecA Streptococcus pneumoniae D39

48.235

100

0.486
  mecA Streptococcus pneumoniae R6

48.235

100

0.486
  mecA Streptococcus pneumoniae TIGR4

48.235

100

0.486

Multiple sequence alignment