Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   BKM66_RS00365 Genome accession   NZ_CP017666
Coordinates   62164..63063 (+) Length   299 a.a.
NCBI ID   WP_105184195.1    Uniprot ID   -
Organism   Streptococcus suis strain 0061     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 58924..61953 62164..63063 flank 211


Gene organization within MGE regions


Location: 58924..63063
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM66_RS00360 (BKM66_00355) - 60482..61953 (-) 1472 Protein_51 IS1182 family transposase -
  BKM66_RS00365 (BKM66_00360) comR 62164..63063 (+) 900 WP_105184195.1 helix-turn-helix domain-containing protein Regulator

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35348.22 Da        Isoelectric Point: 4.3358

>NTDB_id=201278 BKM66_RS00365 WP_105184195.1 62164..63063(+) (comR) [Streptococcus suis strain 0061]
MNDKEFGQRVRQLRETASLTREQFCGDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMEKRADMMTEIYDDYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIQRKPQFSAND
LLIIRLYLINLRMEIKQSSDFQHFLELVEKFPSQVELVESGDLFILRDVMLTSIGILGEHEEYGKIPPLFDALDRIMVST
QDFQKKPILNLLKWKYELYVNNDSEEARRFYEEAVMFAKLIGDTHLVEKLESSWREEEK

Nucleotide


Download         Length: 900 bp        

>NTDB_id=201278 BKM66_RS00365 WP_105184195.1 62164..63063(+) (comR) [Streptococcus suis strain 0061]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACTGCTAGTCTGACACGTGAACAGTTTTGCGGTGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGTATGGGGCTCTATGAGCTTATGCCAGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAG
TTTGATGTCCTCCGTACACCGACTTATGAAAATGAGGAATTGATGGAAAAACGTGCAGATATGATGACAGAAATCTATGA
TGACTATTATGATGACTTGCCTGAAGAAGAGAAAATAGCGATTGATGCCATTCAATCTATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAAATCCAAAGAAAACCCCAATTTTCAGCCAACGAT
TTGTTGATAATTCGACTCTATTTAATCAATTTGAGAATGGAAATTAAACAGAGCAGTGATTTTCAGCACTTTTTAGAGTT
GGTTGAAAAGTTTCCGAGCCAAGTAGAATTAGTTGAATCTGGGGATTTGTTTATTTTAAGGGATGTGATGCTGACGTCGA
TAGGGATTCTTGGCGAACATGAAGAATATGGTAAGATACCTCCACTTTTTGATGCTCTAGATAGAATCATGGTTTCAACT
CAAGATTTTCAAAAGAAACCCATTCTCAATCTGCTTAAGTGGAAATATGAGTTGTATGTGAACAATGATAGCGAGGAGGC
TAGACGGTTTTATGAAGAAGCAGTTATGTTCGCAAAATTAATTGGAGACACCCATTTAGTAGAAAAACTAGAATCATCAT
GGAGAGAAGAGGAAAAGTGA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

67.797

98.662

0.669
  comR Streptococcus suis 05ZYH33

67.797

98.662

0.669
  comR Streptococcus suis D9

61.538

100

0.615
  comR Streptococcus mutans UA159

42.14

100

0.421
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.236

96.321

0.378
  comR Streptococcus pyogenes MGAS8232

37.374

99.331

0.371
  comR Streptococcus pyogenes MGAS315

37.5

98.997

0.371

Multiple sequence alignment