Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SDD27957_00730 Genome accession   CM001076
Coordinates   139672..140703 (+) Length   343 a.a.
NCBI ID   EFY01840.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 134672..145703
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDD27957_00720 - 138349..138714 (+) 366 EFY01838.1 Putative DNA binding protein -
  SDD27957_00725 comYA 138795..139736 (+) 942 EFY01839.1 putative ABC transporter subunit ComYA Machinery gene
  SDD27957_00730 comYB 139672..140703 (+) 1032 EFY01840.1 putative competence protein Machinery gene
  SDD27957_00735 comYC 140705..141031 (+) 327 EFY01841.1 putative competence protein Machinery gene
  SDD27957_00740 - 141006..141434 (+) 429 EFY01842.1 putative competence protein -
  SDD27957_00745 - 141442..141687 (+) 246 EFY01843.1 hypothetical protein -
  SDD27957_00750 - 141668..142108 (+) 441 EFY01844.1 comG operon protein 6 -
  SDD27957_00755 - 142086..142460 (+) 375 EFY01845.1 hypothetical protein -
  SDD27957_00760 comYH 142523..143476 (+) 954 EFY01846.1 adenine-specific methyltransferase Machinery gene
  SDD27957_00765 - 143535..144731 (+) 1197 EFY01847.1 acetate kinase -
  SDD27957_00770 - 145041..145247 (+) 207 EFY01848.1 DNA-binding protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 38959.32 Da        Isoelectric Point: 9.2064

>NTDB_id=20012 SDD27957_00730 EFY01840.1 139672..140703(+) (comYB) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
MTFLQRDISVRSKQGSKKLSSKERYKLIQLLANLLLTGFNLTEIIAFLTKSHLIPEPYVLRMEEALLKGRGLADMLAGIG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVMMLGLRHYVMPHLEAQNQLTIFLTH
FPAIFFGIILFIGVLLGGIWLHWRSQSHLKLFTHLSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMTMEKSL
FMQELAEDIRVSLLAGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWAQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=20012 SDD27957_00730 EFY01840.1 139672..140703(+) (comYB) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
ATGACCTTCTTGCAGCGGGACATCTCAGTCCGAAGCAAGCAAGGATCGAAAAAATTATCCAGTAAGGAACGATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACCTGACGGAGATAATAGCTTTCTTAACAAAAAGTCATCTGA
TTCCCGAGCCCTATGTTCTTCGTATGGAAGAAGCACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGATAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGGAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTTCTGGTATTTCTTT
TTGTAATGATGTTAGGGTTAAGGCATTATGTTATGCCTCACTTAGAAGCTCAAAATCAGCTTACTATTTTTCTCACTCAT
TTTCCAGCTATTTTCTTTGGTATTATCCTTTTTATCGGTGTACTGTTAGGAGGAATTTGGCTGCATTGGCGATCGCAAAG
TCACCTCAAGCTTTTTACTCACCTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGACAGGGACTTGAATTACCAGTCATTCTGGATATTATGACCATGGAGAAATCTTTA
TTTATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTACTGGCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTTAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAGTTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGGCTCAGTTTTTTAGCCAACTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

53.097

98.834

0.525
  comYB Streptococcus mutans UA159

53.097

98.834

0.525
  comYB Streptococcus gordonii str. Challis substr. CH1

48.083

98.834

0.475
  comGB/cglB Streptococcus mitis NCTC 12261

45.97

97.668

0.449
  comGB/cglB Streptococcus mitis SK321

45.345

97.085

0.44
  comGB/cglB Streptococcus pneumoniae Rx1

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae D39

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae R6

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae TIGR4

43.844

97.085

0.426
  comGB Lactococcus lactis subsp. cremoris KW2

42.773

98.834

0.423

Multiple sequence alignment