Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   WH25_RS00910 Genome accession   NZ_CP017295
Coordinates   169828..171186 (-) Length   452 a.a.
NCBI ID   WP_046165176.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 164828..176186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS00885 (WH25_00885) pth 166984..167553 (-) 570 WP_046164770.1 aminoacyl-tRNA hydrolase -
  WH25_RS00890 (WH25_00890) ychF 167627..168742 (-) 1116 WP_008808030.1 redox-regulated ATPase YchF -
  WH25_RS00905 (WH25_00905) comE/comE2 169064..169831 (-) 768 WP_008808031.1 competence system response regulator transcription factor ComE Regulator
  WH25_RS00910 (WH25_00910) comD/comD2 169828..171186 (-) 1359 WP_046165176.1 competence system sensor histidine kinase ComD Regulator
  WH25_RS10570 comC/comC1 171202..171366 (-) 165 WP_080998577.1 bacteriocin Regulator
  WH25_RS00925 (WH25_00925) rlmH 171652..172131 (-) 480 WP_008808034.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  WH25_RS00930 (WH25_00930) htrA 172325..173518 (+) 1194 WP_046164771.1 S1C family serine protease Regulator
  WH25_RS00935 (WH25_00935) spo0J 173584..174348 (+) 765 WP_046164772.1 ParB/RepB/Spo0J family partition protein Regulator
  WH25_RS00940 (WH25_00940) dnaA 174552..175904 (+) 1353 WP_008808037.1 chromosomal replication initiator protein DnaA -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 52641.06 Da        Isoelectric Point: 5.7034

>NTDB_id=197397 WH25_RS00910 WP_046165176.1 169828..171186(-) (comD/comD2) [Streptococcus gordonii strain IE35]
MNFEKIFAIFSLLVQTISFVTVYKKICDIKKLNISIIFLYLTISFSSLILAQFYNLLPEYGDVLSTFLHYLLIFFQPLIL
HLYFSKKGLYKGYVSIFLSLLIYLSVSSSETFFSVIISSVTGDDFVNQYWGSYYTIVNILALFFVLKSFEFFEFEFSYFK
NFDFEKEIMNVIKIYVTIHILLNISHWFSENAHLNSFASMIATIGFIMFLSTLFYLKSAREQHEKAKEIQQKKEEQRQLQ
LYTDEIVGLYNEIRGFRHDYAGMLTSLQTGINSGDMKEVERIFHNVLSQANISLRSDDYTFFELNNVQDTALRSVLIQTI
FKARECGVEIVFEMKDVIETLPMKLLDLVRVASVLLNNAVEGAAESPSKTMNVSLVKLDKEIVFVIQNSRQSRYINLEEI
YEVGFSTKGENRGLGLNNVKEIIDKYDEVILETDIETNYFIQVVRFKRKEKI

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=197397 WH25_RS00910 WP_046165176.1 169828..171186(-) (comD/comD2) [Streptococcus gordonii strain IE35]
ATGAATTTTGAAAAAATATTTGCTATTTTCTCTTTACTAGTTCAAACAATTTCTTTTGTTACTGTATACAAAAAAATATG
TGATATAAAAAAATTAAATATTTCTATCATATTTCTGTACTTAACAATAAGTTTTAGTAGTTTGATATTAGCACAGTTTT
ATAATTTATTACCCGAATATGGAGATGTATTAAGTACTTTCTTACATTACTTACTTATATTTTTCCAACCACTAATCTTA
CATTTATATTTTTCTAAAAAAGGATTATATAAAGGATATGTATCTATCTTTTTATCCCTACTTATATATCTTTCTGTATC
ATCTTCTGAAACTTTTTTCTCAGTTATTATATCTTCAGTGACAGGAGATGATTTTGTTAATCAATACTGGGGTTCTTACT
ATACTATAGTAAATATCTTAGCATTATTTTTTGTTTTGAAATCTTTTGAATTTTTTGAGTTTGAATTTAGTTATTTTAAA
AATTTTGATTTTGAAAAAGAAATAATGAATGTAATTAAAATTTATGTAACGATTCATATCCTATTAAATATTTCTCATTG
GTTTAGCGAAAACGCACATCTTAATAGTTTTGCTAGTATGATTGCCACTATAGGATTTATTATGTTTTTGTCGACTTTAT
TTTATCTAAAGTCTGCTCGTGAACAACATGAAAAAGCAAAAGAAATTCAGCAAAAAAAGGAAGAACAAAGACAACTACAA
CTTTATACAGATGAAATTGTAGGTCTTTATAACGAAATTCGAGGTTTTCGTCACGATTATGCTGGTATGTTAACAAGTTT
GCAAACCGGAATTAACTCAGGTGATATGAAAGAAGTAGAGCGAATCTTTCATAATGTTTTAAGTCAAGCTAATATTTCCC
TTCGATCAGATGACTATACTTTTTTTGAGTTAAATAATGTTCAAGACACTGCCTTGAGAAGTGTGTTAATTCAAACTATA
TTTAAGGCTCGAGAGTGTGGAGTAGAGATCGTATTTGAAATGAAGGATGTTATTGAGACATTACCTATGAAACTTTTAGA
TTTAGTTCGAGTAGCTAGTGTATTGCTCAATAATGCGGTTGAAGGGGCAGCTGAAAGTCCCTCAAAAACAATGAACGTGT
CTTTAGTAAAGCTAGATAAAGAAATTGTTTTTGTAATTCAGAATTCTCGTCAAAGCCGTTACATTAATTTAGAAGAAATT
TATGAAGTAGGCTTCTCGACAAAAGGAGAAAATCGAGGATTAGGTTTAAATAATGTCAAAGAAATTATTGACAAATATGA
TGAAGTTATTCTGGAAACAGATATAGAAACAAATTATTTTATACAAGTTGTAAGATTTAAAAGAAAGGAAAAAATATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(343-444)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

78.076

98.894

0.772
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

76.821

100

0.77
  comD/comD2 Streptococcus pneumoniae TIGR4

49.34

83.85

0.414
  comD/comD1 Streptococcus pneumoniae Rx1

49.077

83.85

0.412
  comD/comD1 Streptococcus pneumoniae D39

49.077

83.85

0.412
  comD/comD1 Streptococcus pneumoniae R6

49.077

83.85

0.412
  comD Streptococcus mitis NCTC 12261

48.285

83.85

0.405
  comD Streptococcus mitis SK321

48.404

83.186

0.403

Multiple sequence alignment