Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   BHS00_RS00395 Genome accession   NZ_CP017194
Coordinates   71523..72770 (-) Length   415 a.a.
NCBI ID   WP_079507705.1    Uniprot ID   -
Organism   Lactococcus carnosus strain TMW 2.1612     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 66523..77770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BHS00_RS00360 (BHS00_00360) - 66955..67701 (+) 747 WP_079507993.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  BHS00_RS00365 (BHS00_00365) - 67694..67960 (+) 267 WP_079507710.1 GIY-YIG nuclease family protein -
  BHS00_RS00370 (BHS00_00370) - 68010..68234 (-) 225 WP_047916414.1 DUF1797 family protein -
  BHS00_RS00375 (BHS00_00375) - 68293..69624 (-) 1332 WP_079507709.1 glycosyltransferase family 4 protein -
  BHS00_RS00380 (BHS00_00380) - 69727..70725 (-) 999 WP_079507708.1 glycosyltransferase -
  BHS00_RS00390 (BHS00_00390) - 71101..71430 (+) 330 WP_079507707.1 bacteriocin immunity protein -
  BHS00_RS00395 (BHS00_00395) htrA 71523..72770 (-) 1248 WP_079507705.1 S1C family serine protease Regulator
  BHS00_RS00400 (BHS00_00400) rlmH 73069..73545 (+) 477 WP_079507703.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  BHS00_RS00405 (BHS00_00405) - 73638..74315 (+) 678 WP_188347498.1 YoaK family protein -
  BHS00_RS00410 (BHS00_00410) - 74554..75333 (+) 780 WP_079507699.1 helix-turn-helix domain-containing protein -
  BHS00_RS00415 (BHS00_00415) - 75655..75978 (+) 324 WP_097025321.1 hypothetical protein -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 43105.42 Da        Isoelectric Point: 6.5268

>NTDB_id=196518 BHS00_RS00395 WP_079507705.1 71523..72770(-) (htrA) [Lactococcus carnosus strain TMW 2.1612]
MKTNKKTAAKLITAGVIGGAVALGGNVVYDHFNTTGTSLNTSSTATKVDNTAYKVTSDTTKAISKVSDAVVSVINYQKAP
ESGSSIDDLFGDRDNKTKKDDAKEQPAAEGSGVIYKKDGDTAYVVTNNHVVDGASSLEILLSNGNKVKGTLVGKDAYSDL
AVIKMAAKDVSKVATFGDSTKLTVGEPAIAIGSPLGSQYANSATEGIISSLSRQVIMKNESNETVNINALQTDAAINPGN
SGGALVNVEGQVIGINSSKISATGASSSDVSVEGMGFAIPSNDVVSIISKLEKDGEIKRPALGVQMLDLASISSQNQAQL
KLPSAVTAGVVIAKVQDGLPAAAAGLKKYDVITKIGDTKVTSGTELQTALYKYNIGDSMKITYYRDGKENTATIKLDNTS
DKLKFDDAEKKNTDK

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=196518 BHS00_RS00395 WP_079507705.1 71523..72770(-) (htrA) [Lactococcus carnosus strain TMW 2.1612]
ATGAAAACAAATAAAAAAACAGCTGCAAAATTAATCACTGCTGGTGTCATAGGTGGTGCTGTCGCCCTAGGTGGTAACGT
CGTTTATGACCACTTCAACACGACTGGTACATCCCTAAATACTAGCAGTACTGCTACTAAGGTTGATAATACAGCCTACA
AAGTCACAAGTGACACAACAAAAGCAATCAGTAAAGTATCTGATGCTGTCGTCTCTGTTATCAATTACCAAAAAGCACCT
GAAAGCGGGTCTTCCATCGATGATCTCTTTGGCGACCGTGATAATAAGACAAAGAAAGATGACGCAAAAGAACAACCTGC
AGCAGAAGGATCTGGGGTCATCTATAAAAAAGATGGCGATACTGCCTATGTTGTCACTAATAACCATGTTGTAGACGGTG
CTAGCTCGCTAGAAATCCTACTTTCTAACGGCAATAAAGTGAAAGGTACATTGGTTGGTAAAGATGCGTATAGCGATTTA
GCTGTCATCAAGATGGCTGCAAAAGATGTCTCTAAAGTGGCAACTTTTGGTGACTCAACAAAACTAACTGTGGGTGAACC
TGCCATCGCAATCGGCTCTCCTCTCGGCAGCCAATACGCCAACTCAGCAACTGAAGGGATTATCTCTAGTCTCTCAAGAC
AAGTCATCATGAAAAACGAAAGTAATGAGACGGTGAATATTAATGCCCTACAAACAGATGCTGCGATAAATCCTGGTAAC
TCTGGTGGTGCGCTCGTTAATGTAGAGGGCCAAGTCATCGGCATTAACTCAAGTAAAATTTCGGCAACAGGTGCCTCTTC
AAGTGATGTTTCTGTTGAAGGAATGGGATTTGCTATTCCCTCAAATGATGTTGTCAGCATCATCAGCAAACTTGAAAAAG
ATGGTGAGATTAAACGTCCGGCACTAGGTGTCCAAATGCTTGATCTTGCAAGCATCAGCTCGCAAAATCAAGCCCAACTC
AAACTCCCTAGCGCAGTCACAGCTGGTGTTGTGATCGCCAAGGTTCAAGATGGGCTACCTGCTGCTGCTGCTGGTCTTAA
GAAATATGATGTCATCACAAAAATTGGGGATACCAAGGTAACAAGTGGTACTGAACTCCAGACAGCACTTTACAAATACA
ATATTGGGGATAGCATGAAAATCACCTATTATCGTGATGGTAAAGAGAACACTGCCACCATTAAACTAGATAATACATCA
GATAAGTTGAAATTTGATGATGCTGAGAAGAAAAATACTGATAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(300-396)

Trypsin-like peptidase domain (Trypsin_2)

(110-255)

Peptidase family M50 (Peptidase_M50)

(284-401)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.478

96.867

0.528
  htrA Streptococcus mutans UA159

55.585

90.602

0.504
  htrA Streptococcus mitis NCTC 12261

53.571

87.711

0.47
  htrA Streptococcus pneumoniae TIGR4

53.221

86.024

0.458
  htrA Streptococcus pneumoniae Rx1

53.221

86.024

0.458
  htrA Streptococcus pneumoniae D39

53.221

86.024

0.458
  htrA Streptococcus pneumoniae R6

53.221

86.024

0.458

Multiple sequence alignment