Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   BFP66_RS10345 Genome accession   NZ_CP017142
Coordinates   2107703..2108899 (+) Length   398 a.a.
NCBI ID   WP_009911075.1    Uniprot ID   G7SHV4
Organism   Streptococcus suis strain GZ0565     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2102703..2113899
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFP66_RS10315 (BFP66_10315) - 2103358..2105937 (+) 2580 WP_024395967.1 YfhO family protein -
  BFP66_RS10335 (BFP66_10335) - 2106342..2107025 (-) 684 WP_024395547.1 YoaK family protein -
  BFP66_RS10340 (BFP66_10340) rlmH 2107050..2107529 (-) 480 WP_015647604.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  BFP66_RS10345 (BFP66_10345) htrA 2107703..2108899 (+) 1197 WP_009911075.1 S1C family serine protease Regulator
  BFP66_RS10350 (BFP66_10350) spo0J 2108960..2109724 (+) 765 WP_012775418.1 ParB/RepB/Spo0J family partition protein Regulator
  BFP66_RS10355 (BFP66_10355) dnaA 2109927..2111300 (+) 1374 WP_024395548.1 chromosomal replication initiator protein DnaA -
  BFP66_RS10360 (BFP66_10360) dnaN 2111454..2112590 (+) 1137 WP_004194538.1 DNA polymerase III subunit beta -
  BFP66_RS10365 (BFP66_10365) - 2112682..2113563 (+) 882 WP_063725132.1 diacylglycerol/lipid kinase family protein -
  BFP66_RS10370 (BFP66_10370) - 2113573..2113776 (+) 204 WP_029172631.1 DUF951 domain-containing protein -

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 41818.83 Da        Isoelectric Point: 4.6655

>NTDB_id=195976 BFP66_RS10345 WP_009911075.1 2107703..2108899(+) (htrA) [Streptococcus suis strain GZ0565]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPRVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=195976 BFP66_RS10345 WP_009911075.1 2107703..2108899(+) (htrA) [Streptococcus suis strain GZ0565]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAGCCACGGGTTCAACAAGCAAATTCTGCCATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCTACTACAAAGGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCCGTTGCTGGGGAGGGATCTGGTGTTAT
CTACAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCTGATACATATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGCCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACCAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTCATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAAAGCGCTCTCTACAAACATCAAATTGGTGACACAATCACTG
TAACCTACTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(293-389)

Trypsin-like peptidase domain (Trypsin_2)

(103-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SHV4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

59.446

99.749

0.593
  htrA Streptococcus gordonii str. Challis substr. CH1

59.494

99.246

0.59
  htrA Streptococcus pneumoniae D39

57.252

98.744

0.565
  htrA Streptococcus pneumoniae TIGR4

57.252

98.744

0.565
  htrA Streptococcus mitis NCTC 12261

57.252

98.744

0.565
  htrA Streptococcus pneumoniae R6

57.252

98.744

0.565
  htrA Streptococcus pneumoniae Rx1

57.252

98.744

0.565

Multiple sequence alignment