Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   A7J08_RS04915 Genome accession   NZ_CP017088
Coordinates   979397..980239 (+) Length   280 a.a.
NCBI ID   WP_148115742.1    Uniprot ID   A0A3S6JK97
Organism   Streptococcus suis strain SRD478     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 974397..985239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS04880 (A7J08_04735) ylqF 974497..975348 (+) 852 WP_011922485.1 ribosome biogenesis GTPase YlqF -
  A7J08_RS04885 (A7J08_04740) - 975335..976108 (+) 774 WP_053866816.1 ribonuclease HII -
  A7J08_RS04890 (A7J08_04745) - 976111..977121 (+) 1011 WP_148115740.1 YdcF family protein -
  A7J08_RS04895 (A7J08_04750) - 977156..977806 (-) 651 WP_105249146.1 hemolysin III family protein -
  A7J08_RS04900 (A7J08_04755) - 977796..978242 (-) 447 WP_148115741.1 DUF1836 domain-containing protein -
  A7J08_RS04905 (A7J08_04760) - 978339..978650 (-) 312 WP_136671102.1 rhodanese-like domain-containing protein -
  A7J08_RS04910 (A7J08_04765) - 978779..979336 (+) 558 WP_136671101.1 sugar O-acetyltransferase -
  A7J08_RS04915 (A7J08_04770) dprA 979397..980239 (+) 843 WP_148115742.1 DNA-processing protein DprA Machinery gene
  A7J08_RS04920 (A7J08_04775) topA 980332..982425 (+) 2094 WP_148115743.1 type I DNA topoisomerase -
  A7J08_RS04925 (A7J08_04780) rplJ 982993..983487 (+) 495 WP_002936486.1 50S ribosomal protein L10 -
  A7J08_RS04930 (A7J08_04785) rplL 983553..983918 (+) 366 WP_002936483.1 50S ribosomal protein L7/L12 -
  A7J08_RS04935 (A7J08_04790) - 984119..984286 (+) 168 WP_032499127.1 hypothetical protein -
  A7J08_RS04940 (A7J08_04795) - 984289..985107 (+) 819 WP_024401260.1 replication initiator protein A -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31278.19 Da        Isoelectric Point: 8.6515

>NTDB_id=195405 A7J08_RS04915 WP_148115742.1 979397..980239(+) (dprA) [Streptococcus suis strain SRD478]
MNNFELFKWKKAGLTNLNVNKVLTYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGVQSVQKIIKELSNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDKVYPKENKDLQTYIGKHHLVLTEYEVGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCITSGLDIISEYQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=195405 A7J08_RS04915 WP_148115742.1 979397..980239(+) (dprA) [Streptococcus suis strain SRD478]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCAGGTTTGACCAATCTTAATGTGAATAAAGTTTTGACCTATCAAGA
AAAACATGGTAAAAAATTGACCTTACGTAATGTCGCTGTAGTGTCTGAATGTAAAAATCCTGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCACTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAACGGTGTTCAGTCAGTTCAGAAGATTATCAAGGAATTGAGTAATCGCT
TTGTCATTGTTAGTGGTTTGGCAAGAGGAATTGATACGGCTGCCCACATCGCCAGTTTGAAAAATGGAGGCCAAACCATT
GCTGTAATTGGAACAGGTTTGGATAAGGTCTATCCCAAAGAAAATAAAGATTTGCAGACCTATATTGGCAAACACCATCT
GGTGCTGACAGAGTATGAAGTTGGTGCTCAGCCACTCAAATACCATTTCCCAGAACGTAACCGCATCATTGCTGGGTTGG
TAGAAGGTCTGGTGGTCTGTGAGGCAAAAATGCGGTCTGGTAGCTTGATTACCTGCGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGGAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGGGCAAAGTG
CATCACATCAGGCTTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3S6JK97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

70.357

100

0.704
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.214

100

0.632
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.214

100

0.632
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.214

100

0.632
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.214

100

0.632
  dprA/cilB/dalA Streptococcus mitis SK321

63.214

100

0.632
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.214

100

0.632
  dprA Lactococcus lactis subsp. cremoris KW2

59.286

100

0.593
  dprA Legionella pneumophila strain ERS1305867

41.296

88.214

0.364
  dprA Bacillus subtilis subsp. subtilis str. 168

50.746

71.786

0.364

Multiple sequence alignment