Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   A7J08_RS04475 Genome accession   NZ_CP017088
Coordinates   885455..886126 (+) Length   223 a.a.
NCBI ID   WP_024400692.1    Uniprot ID   A0A3Q8BJ03
Organism   Streptococcus suis strain SRD478     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 880455..891126
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS04445 (A7J08_04300) pstC 880638..881555 (+) 918 WP_002937619.1 phosphate ABC transporter permease subunit PstC -
  A7J08_RS04450 (A7J08_04305) pstA 881545..882432 (+) 888 WP_105106214.1 phosphate ABC transporter permease PstA -
  A7J08_RS04455 (A7J08_04310) pstB 882457..883260 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  A7J08_RS04460 (A7J08_04315) pstB 883272..884030 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  A7J08_RS04465 (A7J08_04320) phoU 884059..884715 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  A7J08_RS04470 (A7J08_04325) - 884881..885261 (+) 381 WP_148115713.1 hypothetical protein -
  A7J08_RS04475 (A7J08_04330) ciaR 885455..886126 (+) 672 WP_024400692.1 response regulator transcription factor Regulator
  A7J08_RS04480 (A7J08_04335) ciaH 886119..887498 (+) 1380 WP_105178521.1 HAMP domain-containing sensor histidine kinase Regulator
  A7J08_RS04485 - 887668..888956 (-) 1289 Protein_816 IS4 family transposase -
  A7J08_RS04490 (A7J08_04350) - 889453..890682 (+) 1230 WP_053866986.1 transglutaminase domain-containing protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25275.98 Da        Isoelectric Point: 4.2132

>NTDB_id=195403 A7J08_RS04475 WP_024400692.1 885455..886126(+) (ciaR) [Streptococcus suis strain SRD478]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPDKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=195403 A7J08_RS04475 WP_024400692.1 885455..886126(+) (ciaR) [Streptococcus suis strain SRD478]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCAGATGT
TATGCAGGTTTTTGATGGTGAGGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGACAAAGATGGCTTTCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACCACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGAGCTGATGACTACTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGCAAGTTTAATGAAAATACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGCTAGGAAAAGAATTTGACCTACTAGTTTAT
TTCTTGCAAAACCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGATACATTCTAAAAAATGCCTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3Q8BJ03

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

89.686

100

0.897
  ciaR Streptococcus pneumoniae Rx1

87.892

100

0.879
  ciaR Streptococcus pneumoniae D39

87.892

100

0.879
  ciaR Streptococcus pneumoniae R6

87.892

100

0.879
  ciaR Streptococcus pneumoniae TIGR4

87.892

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.053

100

0.386
  vicR Streptococcus mutans UA159

35.043

100

0.368

Multiple sequence alignment