Detailed information NTG0195404

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: A7J08_RS04480
• Genome accession: NZ_CP017088
• Coordinates: 886119..887498 (+)
• Length: 459 a.a.
• NCBI ID: WP_105178521.1
• Uniprot ID: -
• Organism: Streptococcus suis strain SRD478
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	887668..888956	886119..887498	flank	170

Gene organization within MGE regions

Location: 886119..888956

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7J08_RS04480 (A7J08_04335)	ciaH	886119..887498 (+)	1380	WP_105178521.1	HAMP domain-containing sensor histidine kinase	Regulator
A7J08_RS04485	-	887668..888956 (-)	1289	Protein_816	IS4 family transposase	-

Sequence

Protein

• Length: 459 a.a.
• Molecular weight: 51923.61 Da
• Isoelectric Point: 6.8879

>NTDB_id=195404 A7J08_RS04480 WP_105178521.1 886119..887498(+) (ciaH) [Streptococcus suis strain SRD478]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMSVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQIAANIKDKLVCFTVIDNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide

• Length: 1380 bp

>NTDB_id=195404 A7J08_RS04480 WP_105178521.1 886119..887498(+) (ciaH) [Streptococcus suis strain SRD478]
ATGCCTAAGCGATTTAAAAAATTAATGTACACGGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGTCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGCGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCTGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCTTAATCAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGTATCGGATCTAGTTTGGAAGAAGTGCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTAGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGATGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAATTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATGCC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (240-306)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (350-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus pneumoniae Rx1	49.127	99.782	0.49
ciaH	Streptococcus pneumoniae D39	49.127	99.782	0.49
ciaH	Streptococcus pneumoniae R6	49.127	99.782	0.49
ciaH	Streptococcus pneumoniae TIGR4	49.127	99.782	0.49
ciaH	Streptococcus mutans UA159	49.231	99.129	0.488