Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   BFM96_RS07900 Genome accession   NZ_CP016953
Coordinates   1692561..1693235 (+) Length   224 a.a.
NCBI ID   WP_068992692.1    Uniprot ID   A0A917A8Z2
Organism   Streptococcus himalayensis strain HTS2     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1687561..1698235
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS07890 - 1689531..1690787 (-) 1257 WP_068989088.1 ISL3 family transposase -
  BFM96_RS07895 - 1691017..1691976 (+) 960 WP_068992690.1 ROK family glucokinase -
  BFM96_RS07900 ciaR 1692561..1693235 (+) 675 WP_068992692.1 response regulator transcription factor Regulator
  BFM96_RS07905 ciaH 1693225..1694550 (+) 1326 WP_068992694.1 cell wall metabolism sensor histidine kinase WalK Regulator
  BFM96_RS07910 - 1694581..1694781 (+) 201 WP_068992697.1 GIY-YIG nuclease family protein -
  BFM96_RS07915 - 1694898..1696355 (-) 1458 WP_068992699.1 alpha-amylase -
  BFM96_RS07920 - 1696435..1696950 (-) 516 WP_068992702.1 DNA topology modulation protein -
  BFM96_RS07925 rpsT 1697017..1697268 (-) 252 WP_083201774.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25446.22 Da        Isoelectric Point: 4.4351

>NTDB_id=194055 BFM96_RS07900 WP_068992692.1 1692561..1693235(+) (ciaR) [Streptococcus himalayensis strain HTS2]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKGSTTPVLIMTA
KESLNDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLSYGDIRINLATNTTLIKDNPVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTAFANNLHTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=194055 BFM96_RS07900 WP_068992692.1 1692561..1693235(+) (ciaR) [Streptococcus himalayensis strain HTS2]
ATGATAAAAATTCTCTTGGTAGAGGACGACCTAGGTTTGTCCAATTCTGTGTTTGATTTTTTAGACGATTTTGCGGATGT
CATGCAGGTTTTCGATGGAGAAGAAGGCTTGTATGAGGCCGAAAGTGGCGTCTATGATTTGATTTTACTAGACTTGATGT
TGCCAGAAAAAGATGGTTTTCAAGTCTTAAAAGAATTGCGGGAAAAGGGGAGTACAACTCCTGTCTTAATCATGACCGCA
AAGGAAAGTTTGAATGACAAGGGACATGGATTTGAGCTTGGAGCTGATGATTACCTGACCAAACCCTTTTATTTAGAAGA
GTTGAAAATGCGAATCCAGGCACTTTTGAAACGCTCTGGAAAATTCAATGAAAATACCTTGTCTTATGGGGATATTCGTA
TCAATTTAGCCACAAATACAACCTTGATCAAGGATAATCCAGTTGAATTATTGGGGAAAGAGTTTGATTTATTGGTCTAT
TTCTTGCAAAATCAAAATGTCATTTTGCCCAAAACTCAGATTTTTGATCGTTTGTGGGGATTTGACAGCGATACGACTAT
TTCGGTTGTAGAGGTCTATGTGTCGAAAATTCGAAAGAAATTGAAAGGGACGGCTTTTGCGAACAATTTGCACACCCTTC
GCAGTGTCGGATATATATTAAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae TIGR4

91.071

100

0.911
  ciaR Streptococcus pneumoniae D39

91.071

100

0.911
  ciaR Streptococcus pneumoniae R6

91.071

100

0.911
  ciaR Streptococcus pneumoniae Rx1

91.071

100

0.911
  ciaR Streptococcus mutans UA159

87.444

99.554

0.871
  vicR Streptococcus mutans UA159

36.052

100

0.375
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.168

100

0.375

Multiple sequence alignment