Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   BFM96_RS07905 Genome accession   NZ_CP016953
Coordinates   1693225..1694550 (+) Length   441 a.a.
NCBI ID   WP_068992694.1    Uniprot ID   A0A917EHI2
Organism   Streptococcus himalayensis strain HTS2     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1688225..1699550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS07890 - 1689531..1690787 (-) 1257 WP_068989088.1 ISL3 family transposase -
  BFM96_RS07895 - 1691017..1691976 (+) 960 WP_068992690.1 ROK family glucokinase -
  BFM96_RS07900 ciaR 1692561..1693235 (+) 675 WP_068992692.1 response regulator transcription factor Regulator
  BFM96_RS07905 ciaH 1693225..1694550 (+) 1326 WP_068992694.1 cell wall metabolism sensor histidine kinase WalK Regulator
  BFM96_RS07910 - 1694581..1694781 (+) 201 WP_068992697.1 GIY-YIG nuclease family protein -
  BFM96_RS07915 - 1694898..1696355 (-) 1458 WP_068992699.1 alpha-amylase -
  BFM96_RS07920 - 1696435..1696950 (-) 516 WP_068992702.1 DNA topology modulation protein -
  BFM96_RS07925 rpsT 1697017..1697268 (-) 252 WP_083201774.1 30S ribosomal protein S20 -
  BFM96_RS07930 coaA 1697322..1698242 (-) 921 WP_068992708.1 type I pantothenate kinase -
  BFM96_RS07935 - 1698332..1698919 (+) 588 WP_068992711.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50502.04 Da        Isoelectric Point: 9.3775

>NTDB_id=194056 BFM96_RS07905 WP_068992694.1 1693225..1694550(+) (ciaH) [Streptococcus himalayensis strain HTS2]
MLNKFKTTWYSDNFSYFLRNFGVFTLIFSAMTLIILQVMRSSLYVSVDNKITELSQKPSSVINMVLRREEVNFAKDLQGY
QVDESDLLDVSANTEVILFNKDYEAITTGDNFLGLNNLAFDKRQMNRIRQVQVKNGYGGEETYRMMVFPCQDAKGSLVKY
AAIFINTSQLEQANLSHEQVVIMVMVSFWLLSVVASIYLASVSVKPLLESMQKQKSFVENASHELRTPLAVLQNRLETLF
RKPEATIMDSSESIASSLEEVRNMRMLTTNLLNLARRDDGITPEIVDVDQNFFNTTFTNYEMIATENGKTFRFQNKIFRT
IRTDKTLLKQLMTILFDNAIKYTDEDGEIELTVSANDRTLFLTVEDNGAGIRNEDKKRVFDRFYRIDKARTRQKGGFGLG
LSLAKQIVEALKGTITVKDNKPRGTIFEVKIAIKTDNKKKK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=194056 BFM96_RS07905 WP_068992694.1 1693225..1694550(+) (ciaH) [Streptococcus himalayensis strain HTS2]
ATGCTGAATAAGTTTAAAACAACCTGGTATTCGGATAATTTTAGCTATTTTTTGAGAAATTTTGGCGTCTTTACCCTGAT
TTTCTCAGCCATGACCCTGATTATTTTACAGGTCATGCGATCTAGTTTGTATGTCTCTGTCGATAATAAAATTACAGAAT
TGAGCCAAAAGCCTAGTTCAGTCATTAACATGGTTCTCCGAAGAGAAGAAGTCAATTTTGCTAAGGATTTGCAAGGTTAT
CAGGTAGATGAATCCGATTTGCTGGATGTCAGTGCGAATACAGAGGTGATTTTATTTAACAAGGATTATGAAGCCATTAC
CACAGGGGATAATTTTCTGGGTTTGAATAATCTCGCTTTTGATAAGCGACAAATGAATCGCATTCGTCAAGTTCAAGTGA
AAAATGGTTACGGTGGAGAAGAAACCTATCGGATGATGGTCTTTCCTTGCCAAGACGCTAAAGGCAGTCTCGTGAAGTAT
GCGGCCATTTTCATCAATACGAGCCAGTTGGAGCAAGCCAATTTAAGCCATGAACAAGTCGTCATTATGGTAATGGTAAG
TTTTTGGCTGTTATCTGTGGTTGCAAGTATCTATTTAGCCAGCGTCAGTGTCAAGCCTCTTTTGGAGAGTATGCAAAAGC
AGAAATCCTTTGTTGAAAATGCCAGTCATGAATTACGAACTCCTTTAGCAGTTCTTCAAAATCGCTTGGAAACCCTTTTT
AGAAAGCCAGAAGCGACCATTATGGATTCTAGCGAGAGCATTGCCTCAAGCCTTGAAGAAGTTCGAAATATGCGAATGCT
GACGACTAATCTGCTCAATCTCGCCCGTCGAGATGATGGAATCACGCCAGAAATTGTGGATGTCGATCAAAATTTCTTTA
ACACGACCTTTACCAATTATGAAATGATTGCAACGGAAAATGGAAAAACTTTTCGGTTTCAAAATAAGATTTTCCGAACG
ATTCGAACCGATAAGACCCTACTCAAGCAGTTGATGACCATTTTATTTGACAATGCCATTAAATATACGGATGAGGATGG
CGAAATTGAATTGACTGTTTCGGCCAATGATCGCACCCTTTTTCTGACAGTGGAAGACAATGGGGCGGGCATCCGAAATG
AGGATAAGAAAAGAGTATTTGACCGCTTTTATCGGATTGATAAGGCGAGAACTCGTCAAAAAGGTGGTTTTGGATTAGGC
TTATCCTTGGCCAAGCAAATCGTTGAAGCCCTCAAAGGGACCATTACGGTGAAAGATAATAAACCTCGCGGAACCATTTT
TGAAGTAAAAATCGCTATTAAAACGGATAATAAAAAAAAGAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-431)

His Kinase A (phospho-acceptor) domain (HisKA)

(215-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

68.009

100

0.689
  ciaH Streptococcus pneumoniae D39

68.009

100

0.689
  ciaH Streptococcus pneumoniae R6

68.009

100

0.689
  ciaH Streptococcus pneumoniae TIGR4

68.009

100

0.689
  ciaH Streptococcus mutans UA159

55.658

98.186

0.546

Multiple sequence alignment