Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   BFM96_RS05080 Genome accession   NZ_CP016953
Coordinates   1068533..1069201 (+) Length   222 a.a.
NCBI ID   WP_068991168.1    Uniprot ID   A0A917A5P1
Organism   Streptococcus himalayensis strain HTS2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1063533..1074201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS05055 - 1063590..1064993 (+) 1404 WP_068991155.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  BFM96_RS05060 - 1064990..1065349 (+) 360 WP_068991158.1 S1 RNA-binding domain-containing protein -
  BFM96_RS05065 cysK 1065513..1066442 (-) 930 WP_068991161.1 cysteine synthase A -
  BFM96_RS05070 - 1066548..1067180 (-) 633 WP_068991164.1 YigZ family protein -
  BFM96_RS05075 comFA/cflA 1067235..1068536 (+) 1302 WP_068991167.1 DEAD/DEAH box helicase Machinery gene
  BFM96_RS05080 comFC/cflB 1068533..1069201 (+) 669 WP_068991168.1 ComF family protein Machinery gene
  BFM96_RS05085 hpf 1069279..1069821 (+) 543 WP_068991173.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  BFM96_RS05090 - 1069885..1070811 (+) 927 WP_068991176.1 aldo/keto reductase family oxidoreductase -
  BFM96_RS05095 - 1071566..1072792 (-) 1227 WP_068991179.1 transporter -
  BFM96_RS05100 - 1072913..1073416 (-) 504 WP_229676521.1 hypothetical protein -
  BFM96_RS10830 - 1073486..1073779 (-) 294 WP_083201745.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 26155.14 Da        Isoelectric Point: 8.4006

>NTDB_id=194035 BFM96_RS05080 WP_068991168.1 1068533..1069201(+) (comFC/cflB) [Streptococcus himalayensis strain HTS2]
MNHCLLCHHPLKQHYRFLDLLLLKKQAVFTCDTCMSEFKEIGEQHCERCWKEGEDVLCSDCQEWEKKGEMIEHQACFRYN
QAMKEYFSTYKFQGDYALHRVFARTFSRALKPYQKEFTLVPIPVSSHRFQKRGFNQVTAFLEGAKLSYSDLLEKEDSLAQ
SSKTREERLQTQQVFSIRDLKNLPEKILLIDDIYTTGATLHLAKKLLLENGVKRVRTFSLAR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=194035 BFM96_RS05080 WP_068991168.1 1068533..1069201(+) (comFC/cflB) [Streptococcus himalayensis strain HTS2]
ATGAACCATTGTTTGCTTTGTCACCATCCCTTGAAACAACACTATCGTTTTTTAGACCTTCTTCTTTTGAAGAAGCAGGC
TGTTTTTACCTGTGATACTTGTATGTCAGAGTTTAAGGAGATTGGCGAGCAGCATTGTGAACGTTGCTGGAAAGAAGGAG
AAGATGTACTTTGTTCTGATTGTCAAGAGTGGGAGAAAAAGGGAGAAATGATAGAGCATCAAGCCTGTTTTCGCTACAAT
CAAGCCATGAAAGAATATTTCAGTACCTATAAATTTCAAGGTGATTATGCTCTTCATCGAGTATTTGCAAGGACTTTTTC
CCGTGCTTTAAAGCCGTACCAAAAGGAGTTTACACTGGTTCCCATACCTGTGAGCAGTCATCGATTTCAAAAAAGAGGGT
TTAATCAAGTAACGGCTTTTTTAGAAGGAGCAAAGCTCTCTTATAGTGACTTGTTGGAAAAAGAGGATAGCCTTGCCCAA
TCTAGTAAAACGCGAGAAGAAAGGTTGCAGACCCAACAGGTATTTTCAATCCGAGATTTGAAAAATCTTCCAGAGAAAAT
CCTTTTGATTGATGATATTTATACGACAGGAGCTACACTTCATTTAGCAAAGAAACTTCTTTTGGAAAACGGGGTGAAAA
GAGTACGGACATTTTCACTTGCACGATAA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(170-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis NCTC 12261

50.685

98.649

0.5
  comFC/cflB Streptococcus pneumoniae Rx1

50.685

98.649

0.5
  comFC/cflB Streptococcus pneumoniae D39

50.685

98.649

0.5
  comFC/cflB Streptococcus pneumoniae R6

50.685

98.649

0.5
  comFC/cflB Streptococcus pneumoniae TIGR4

50.685

98.649

0.5
  comFC/cflB Streptococcus mitis SK321

49.315

98.649

0.486
  comFC Bacillus subtilis subsp. subtilis str. 168

35.242

100

0.36

Multiple sequence alignment