Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   BFM96_RS05075 Genome accession   NZ_CP016953
Coordinates   1067235..1068536 (+) Length   433 a.a.
NCBI ID   WP_068991167.1    Uniprot ID   -
Organism   Streptococcus himalayensis strain HTS2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1062235..1073536
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS05050 - 1062881..1063513 (+) 633 WP_068991152.1 response regulator transcription factor -
  BFM96_RS05055 - 1063590..1064993 (+) 1404 WP_068991155.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  BFM96_RS05060 - 1064990..1065349 (+) 360 WP_068991158.1 S1 RNA-binding domain-containing protein -
  BFM96_RS05065 cysK 1065513..1066442 (-) 930 WP_068991161.1 cysteine synthase A -
  BFM96_RS05070 - 1066548..1067180 (-) 633 WP_068991164.1 YigZ family protein -
  BFM96_RS05075 comFA/cflA 1067235..1068536 (+) 1302 WP_068991167.1 DEAD/DEAH box helicase Machinery gene
  BFM96_RS05080 comFC/cflB 1068533..1069201 (+) 669 WP_068991168.1 ComF family protein Machinery gene
  BFM96_RS05085 hpf 1069279..1069821 (+) 543 WP_068991173.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  BFM96_RS05090 - 1069885..1070811 (+) 927 WP_068991176.1 aldo/keto reductase family oxidoreductase -
  BFM96_RS05095 - 1071566..1072792 (-) 1227 WP_068991179.1 transporter -
  BFM96_RS05100 - 1072913..1073416 (-) 504 WP_229676521.1 hypothetical protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49430.01 Da        Isoelectric Point: 8.0298

>NTDB_id=194034 BFM96_RS05075 WP_068991167.1 1067235..1068536(+) (comFA/cflA) [Streptococcus himalayensis strain HTS2]
MMERKDCLGRLFTSQQLPEELRDIAERLPSMVESKGELRCSRCWSPVDKELSRLPVGAYYCRECLLLGRVRSDEPLYYFP
QEAYPSQQVLKWTGQLTEFQHKVSEGLLAAWEKRENTLVHAVTGAGKTEMIYPLVASVIDSGGAVCMASPRIDVCLELYR
RLKEDFSCPISLLHGESEPYFRSPLVIATTHQLLKFYQAFDLLVVDEVDAFPYVDNPMLYHAVSQSVKKDGQTVFLTATS
TDELDRKVRKGTLKRLSLPRRFHGNALIVPQKVWLANFQTYLSKNQLPPRLEKMIDQQRRTGFPLLIFASEIKRGQAFAA
VLQKYFPDERVGFVASTTENRLELVEQFRQKELTILVSTTILERGVTFPCVDVFVLEANHRLFTRSALVQISGRVGRSME
RPTGALYFFQDGTNQAIEKAIQEIKQMNQEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=194034 BFM96_RS05075 WP_068991167.1 1067235..1068536(+) (comFA/cflA) [Streptococcus himalayensis strain HTS2]
ATGATGGAAAGAAAAGATTGTTTAGGGCGTTTGTTTACTAGCCAGCAGTTACCAGAGGAGTTGCGAGACATAGCAGAGCG
GCTTCCTAGCATGGTGGAGTCTAAGGGGGAGTTGCGGTGCAGTCGTTGTTGGAGTCCTGTGGATAAGGAATTATCCAGGC
TGCCTGTAGGGGCTTATTATTGCCGAGAGTGTTTGTTATTAGGTCGTGTTCGTAGCGATGAGCCTCTCTATTATTTTCCA
CAGGAAGCCTATCCTTCTCAGCAGGTTTTAAAATGGACAGGGCAGCTGACAGAGTTTCAACATAAGGTTTCAGAAGGGCT
ACTTGCGGCATGGGAAAAAAGAGAGAATACCTTGGTTCATGCGGTCACAGGTGCTGGAAAGACAGAGATGATTTATCCCT
TGGTTGCTAGTGTGATTGATAGCGGAGGAGCTGTTTGTATGGCCAGTCCACGAATTGATGTCTGCTTGGAGTTGTATCGT
CGGTTAAAAGAAGATTTTTCTTGTCCCATTTCCCTCCTTCATGGGGAATCAGAACCCTATTTTCGGAGTCCTCTAGTCAT
TGCTACTACTCATCAGTTATTAAAGTTTTATCAGGCGTTTGATTTGTTGGTCGTTGATGAGGTGGATGCTTTTCCCTATG
TGGATAATCCTATGCTTTATCACGCTGTTTCCCAATCGGTCAAAAAAGATGGTCAGACTGTTTTTTTGACAGCTACCTCA
ACAGATGAATTGGATAGAAAGGTTCGAAAAGGAACTTTGAAACGTCTCAGTTTGCCTCGCCGCTTCCACGGCAATGCGCT
CATCGTACCGCAGAAGGTTTGGTTGGCAAATTTTCAAACCTATCTGTCAAAAAATCAACTTCCTCCAAGATTGGAAAAAA
TGATTGATCAGCAGAGGAGGACTGGCTTTCCCTTGTTAATCTTTGCATCGGAAATCAAGCGAGGGCAAGCATTTGCAGCT
GTTTTACAGAAATATTTCCCAGATGAACGTGTGGGGTTCGTCGCCTCAACCACGGAAAATCGCTTAGAATTGGTCGAGCA
ATTTCGCCAGAAGGAATTAACCATCTTGGTGTCTACAACTATTTTGGAGCGAGGAGTTACTTTTCCTTGTGTAGACGTCT
TTGTACTTGAAGCCAATCATCGCTTGTTTACACGAAGTGCCCTGGTACAAATCAGTGGCCGTGTGGGACGGAGTATGGAG
AGGCCAACAGGTGCTCTCTATTTCTTTCAAGATGGCACCAATCAAGCGATTGAAAAAGCCATTCAAGAAATTAAACAGAT
GAATCAGGAGGCAGGATTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(99-244)

Helicase conserved C-terminal domain (Helicase_C)

(294-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

70.561

98.845

0.697
  comFA/cflA Streptococcus pneumoniae D39

70.561

98.845

0.697
  comFA/cflA Streptococcus pneumoniae R6

70.561

98.845

0.697
  comFA/cflA Streptococcus pneumoniae TIGR4

70.327

98.845

0.695
  comFA/cflA Streptococcus mitis NCTC 12261

70.657

98.383

0.695
  comFA/cflA Streptococcus mitis SK321

70.423

98.383

0.693
  comFA Lactococcus lactis subsp. cremoris KW2

51.25

92.379

0.473
  comFA Latilactobacillus sakei subsp. sakei 23K

38.837

99.307

0.386
  comFA Bacillus subtilis subsp. subtilis str. 168

39.024

94.688

0.37

Multiple sequence alignment