Detailed information NTG0194009

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: BFM96_RS04180
• Genome accession: NZ_CP016953
• Coordinates: 865611..866966 (+)
• Length: 451 a.a.
• NCBI ID: WP_068990716.1
• Uniprot ID: A0A917AAP6
• Organism: Streptococcus himalayensis strain HTS2
• Function: transport of ComC (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	867213..868469	865611..866966	flank	247

Gene organization within MGE regions

Location: 865611..868469

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BFM96_RS04180	comB	865611..866966 (+)	1356	WP_068990716.1	bacteriocin secretion accessory protein	Regulator
BFM96_RS04185	-	867213..868469 (+)	1257	WP_068990719.1	ISL3 family transposase	-

Sequence

Protein

• Length: 451 a.a.
• Molecular weight: 49479.50 Da
• Isoelectric Point: 5.0101

>NTDB_id=194009 BFM96_RS04180 WP_068990716.1 865611..866966(+) (comB) [Streptococcus himalayensis strain HTS2]
MNEQFLESAEFYNRRYHNFSSRVILPAFVLLLFLLSFAFLAKKELTISAGASIEPESILVNIQSTSNNAIIENHLEENKV
VKKGQVLVKYKLEGEQAQQATLSSQLETLKEQKGQLELLKASLESGSSQFPAADKFGYEQNFQDYLNQAASLSANTEQQN
ATIASQNAAASNSQAELGNIINETNAKIADYRAVKSAIQTGASLDPTTSGYEIYQAYSAQVTDGSQEQLKSQYLAQVDGQ
ISQLESALSGYRLQYAGSGAQQAYSGSLPSQLESLKAQNLARVGQEMTALEQKIMEVEGNSKIQAGLTQKGEILALEDGI
IHLNPETKSSSLVPEGTLLAQLYPNLVENSKVKITSYISSKDISSIKEGDKVRFTTVDDANKQMSLTSTISSIDSSATKT
EKGNFFKIEVKITLTKKEAATLRYGLEGRLVMITGQKTYFDYYKDKFLNQS

Nucleotide

• Length: 1356 bp

>NTDB_id=194009 BFM96_RS04180 WP_068990716.1 865611..866966(+) (comB) [Streptococcus himalayensis strain HTS2]
ATGAACGAACAATTTTTAGAAAGTGCTGAGTTTTACAACCGTCGCTACCATAATTTCTCAAGCCGTGTGATTTTGCCAGC
CTTTGTCCTCCTACTCTTTCTTCTATCCTTTGCTTTTTTAGCCAAGAAAGAGCTGACTATCTCTGCAGGGGCTAGTATTG
AGCCTGAAAGCATTTTAGTTAATATCCAATCAACCAGCAATAACGCTATTATTGAAAACCATTTAGAAGAAAATAAAGTT
GTTAAAAAGGGGCAAGTACTTGTCAAATACAAGCTAGAAGGAGAACAGGCGCAACAAGCAACCCTTTCTTCCCAACTAGA
AACCCTAAAAGAACAAAAAGGCCAGTTAGAACTACTCAAAGCCAGTCTTGAATCTGGATCTAGCCAATTTCCTGCAGCAG
ATAAATTTGGCTATGAACAAAATTTTCAAGACTATCTTAATCAAGCAGCTAGTTTAAGTGCAAATACGGAGCAACAAAAT
GCCACTATTGCTTCTCAAAACGCAGCCGCAAGTAATTCTCAAGCAGAACTAGGTAACATTATCAATGAAACCAATGCCAA
GATTGCAGATTATCGAGCAGTTAAATCTGCTATCCAAACAGGGGCTAGCTTAGACCCCACAACAAGTGGCTATGAGATTT
ACCAAGCCTACAGTGCCCAAGTAACCGATGGTTCTCAAGAACAGCTCAAAAGTCAATACCTGGCGCAAGTAGATGGTCAA
ATCAGTCAATTAGAATCTGCCCTATCTGGCTATCGCTTGCAATATGCAGGATCAGGAGCTCAACAGGCTTATTCTGGGAG
CCTTCCTAGCCAGCTAGAATCTCTCAAAGCGCAAAATCTAGCTAGGGTTGGTCAAGAAATGACAGCACTCGAACAAAAAA
TTATGGAAGTTGAAGGAAATAGCAAGATTCAAGCAGGCTTAACTCAAAAAGGAGAAATCCTCGCCCTAGAAGATGGGATT
ATCCACCTCAACCCCGAAACAAAAAGCTCTAGTCTGGTTCCTGAAGGAACCCTCCTAGCCCAGCTTTACCCAAATCTAGT
AGAAAATAGCAAGGTAAAAATCACCAGCTATATCTCCTCGAAGGACATCTCTAGTATCAAAGAAGGGGATAAAGTTCGCT
TTACGACTGTCGATGACGCCAATAAGCAAATGAGCCTAACATCTACTATTTCTAGCATTGATAGCAGTGCGACAAAGACA
GAGAAAGGAAATTTCTTCAAGATTGAAGTAAAAATTACCCTCACAAAAAAAGAGGCAGCTACTCTGCGATATGGTCTAGA
AGGACGCTTGGTCATGATTACAGGACAAAAGACTTACTTTGATTACTATAAAGACAAGTTTTTGAATCAGTCATGA

Domains

Predicted by InterproScan.

• HlyD family secretion protein (HlyD_3) (313-425)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus pneumoniae R6	59.778	99.778	0.596
comB	Streptococcus pneumoniae Rx1	59.778	99.778	0.596
comB	Streptococcus pneumoniae D39	59.778	99.778	0.596
comB	Streptococcus mitis NCTC 12261	59.778	99.778	0.596
comB	Streptococcus pneumoniae TIGR4	59.556	99.778	0.594
comB	Streptococcus mitis SK321	59.556	99.778	0.594
comB	Streptococcus gordonii str. Challis substr. CH1	57.743	100	0.579