Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   BFM96_RS04175 Genome accession   NZ_CP016953
Coordinates   863444..865597 (+) Length   717 a.a.
NCBI ID   WP_068990713.1    Uniprot ID   A0A917AA80
Organism   Streptococcus himalayensis strain HTS2     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 858444..870597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS04150 - 859074..859751 (+) 678 WP_068990697.1 LemA family protein -
  BFM96_RS04155 - 859778..861022 (+) 1245 WP_068990700.1 aminopeptidase -
  BFM96_RS04160 - 861037..861267 (+) 231 WP_068990704.1 GlsB/YeaQ/YmgE family stress response membrane protein -
  BFM96_RS10810 - 861280..861387 (+) 108 Protein_783 16S rRNA (uracil(1498)-N(3))-methyltransferase -
  BFM96_RS04165 - 861528..862238 (+) 711 WP_068990706.1 PoNe immunity protein domain-containing protein -
  BFM96_RS04175 comA 863444..865597 (+) 2154 WP_068990713.1 peptide cleavage/export ABC transporter ComA Regulator
  BFM96_RS04180 comB 865611..866966 (+) 1356 WP_068990716.1 bacteriocin secretion accessory protein Regulator
  BFM96_RS04185 - 867213..868469 (+) 1257 WP_068990719.1 ISL3 family transposase -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80544.60 Da        Isoelectric Point: 7.0554

>NTDB_id=194008 BFM96_RS04175 WP_068990713.1 863444..865597(+) (comA) [Streptococcus himalayensis strain HTS2]
MKFGKRHYRPQVDSRDCGVASLAMVFGFYGSRYSLASLREMAKTTMEGTTAFGLVKVAQELGFETRALKADMTLFDMEDL
TYPFIAHVLKEGKLLHYYVVIGQDKKSIHIADPDPAVKITKLPRKRFEEEWTGVTIFLAPTPEYKPHKEKKNGLLSFLPI
LTKQRGLITNIILATFLVTLINIVGSYYLQSIIDTYVPDQMKNTLGMISLGLVIVYILQQVLAYAQDYLLLILGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVLIISVVLFSQNIHLFFISLLALPIYSV
IIFAFMKPFENMNRDTMEANAVLSSSIIEDINGIETIKSLTSESHRYQKIDKEFVDYLKKSFAYSRAESQQKALKKVAQL
LLNVAILWMGAILVMDNQMTLGQLITYNTLLIYFTNPLENIINLQTKLQTAQVANNRLNEVYLVESEFADKKTVQDLSMV
AGDIDFKDVSYKYGYGKDVLSDINLSIKHGSKVAFVGISGSGKTTLAKMIVNFYDPSKGEITLNNINLNQIDKHALRQHI
NYLPQQPYVFNGTILDNLLLGAKEGTTQEDILRAVELAEIRADIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEHVVVLNQGQIIEQGTHQELLAKNGFYANLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=194008 BFM96_RS04175 WP_068990713.1 863444..865597(+) (comA) [Streptococcus himalayensis strain HTS2]
ATGAAGTTTGGAAAACGGCATTATCGTCCTCAAGTAGATAGTCGGGATTGTGGGGTTGCCTCACTTGCTATGGTCTTTGG
TTTTTATGGTTCCAGATACTCTCTTGCCAGTCTTCGTGAAATGGCAAAGACTACTATGGAAGGCACGACTGCCTTTGGCT
TGGTCAAGGTCGCTCAAGAGCTTGGCTTTGAAACACGTGCTCTTAAGGCAGATATGACCCTCTTTGACATGGAAGATTTG
ACCTATCCCTTTATTGCCCATGTGCTCAAAGAAGGTAAACTTCTTCATTATTACGTCGTGATTGGCCAAGACAAAAAATC
CATTCATATTGCTGATCCAGACCCTGCCGTTAAAATCACCAAACTCCCTCGCAAACGATTTGAAGAAGAATGGACAGGGG
TCACCATCTTTCTTGCTCCAACACCTGAATACAAACCACACAAAGAGAAGAAAAATGGGCTTCTCTCTTTCTTGCCGATT
CTTACCAAACAAAGAGGGTTGATTACCAATATCATTCTTGCTACCTTTCTAGTCACTCTCATCAATATTGTCGGCTCTTA
CTATCTTCAATCCATTATTGATACCTATGTGCCGGATCAGATGAAAAATACCTTGGGAATGATTTCGCTAGGGCTTGTCA
TCGTCTATATCTTGCAACAGGTGCTCGCCTATGCTCAGGACTATCTGCTCTTGATTTTGGGGCAACGTTTGTCGATTGAT
GTGATTCTATCTTATATCAAACATGTCTTTCATCTACCCATGTCCTTTTTTGCGACTCGTAGGACTGGGGAGATTGTTTC
CCGTTTTACCGACGCAAATAGTATCATTGACGCTCTAGCCTCTACTATCTTATCCATATTTCTGGACGTTTCAACGGTGC
TCATTATCTCAGTCGTTCTTTTCTCCCAAAACATCCATCTCTTCTTTATCAGTCTCTTGGCCTTGCCTATTTACTCCGTT
ATCATCTTTGCCTTTATGAAACCTTTTGAAAATATGAATCGAGATACTATGGAAGCTAATGCCGTGCTCTCCTCTTCTAT
CATCGAGGATATTAACGGAATTGAAACCATTAAATCCTTGACCAGCGAGAGTCATCGCTATCAAAAGATTGATAAGGAAT
TTGTCGATTATCTCAAAAAATCCTTTGCTTATAGCCGAGCGGAGAGCCAACAGAAGGCTCTGAAAAAAGTAGCTCAGCTC
CTTTTAAATGTTGCTATTCTTTGGATGGGAGCGATTCTGGTCATGGATAATCAAATGACCTTAGGGCAGCTGATTACTTA
CAATACCTTACTCATTTACTTTACCAATCCATTAGAAAATATCATCAATCTCCAAACCAAACTCCAGACTGCCCAAGTGG
CTAATAATCGCTTGAATGAGGTCTATTTGGTGGAGTCCGAATTTGCCGATAAAAAGACTGTGCAAGACCTGAGTATGGTG
GCTGGAGATATTGATTTTAAAGATGTCAGCTATAAATACGGCTATGGGAAAGATGTCTTATCTGATATCAATTTATCTAT
CAAACACGGCAGTAAGGTTGCCTTTGTTGGCATTTCTGGCTCTGGGAAAACAACCTTAGCCAAAATGATTGTGAATTTCT
ACGATCCTTCAAAGGGAGAAATTACACTCAACAATATCAACCTCAATCAGATTGACAAGCATGCGCTACGGCAACATATC
AACTATCTGCCCCAACAGCCTTATGTTTTTAATGGAACCATTTTAGACAATCTGCTCCTAGGGGCGAAAGAAGGAACAAC
GCAAGAAGACATTCTACGAGCAGTTGAACTAGCTGAGATTCGAGCAGATATTGAGCGTATGCCCCTCAATTACCAAACAG
AATTGACTTCAGATGGGGCAGGGATTTCTGGTGGTCAACGACAACGGATTGCCCTGGCACGTGCTCTTTTGACCGATGCT
CCTGTATTGATTCTTGATGAGGCGACCAGTAGCCTCGACATTCTGACTGAAAAACGGATTGTCGATAATCTCATGGCTCT
AGATAAGACACTCATCTTTATTGCACACCGTTTGACCATTGCCGAGCGAACAGAACATGTAGTGGTGCTCAATCAAGGAC
AAATTATCGAACAAGGAACTCACCAAGAACTCTTGGCGAAAAATGGTTTTTATGCCAACTTGGTCAATAGCTAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter (ABC_tran)

(500-650)

ABC transporter transmembrane region (ABC_membrane)

(169-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

87.308

100

0.873
  comA Streptococcus mitis SK321

86.75

100

0.868
  comA Streptococcus pneumoniae Rx1

86.75

100

0.868
  comA Streptococcus pneumoniae D39

86.75

100

0.868
  comA Streptococcus pneumoniae R6

86.75

100

0.868
  comA Streptococcus pneumoniae TIGR4

86.471

100

0.865
  comA Streptococcus gordonii str. Challis substr. CH1

78.522

100

0.785
  comA/nlmT Streptococcus mutans UA159

66.248

100

0.662

Multiple sequence alignment