Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   BAY21_RS05605 Genome accession   NZ_CP016439
Coordinates   1046769..1047869 (+) Length   366 a.a.
NCBI ID   WP_148148889.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS8     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1041769..1052869
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BAY21_RS05595 (BAY21_05595) - 1045503..1045865 (+) 363 WP_011226630.1 DUF1033 family protein -
  BAY21_RS05600 (BAY21_05600) comGA/cglA/cilD 1045946..1046887 (+) 942 WP_011226629.1 competence type IV pilus ATPase ComGA Machinery gene
  BAY21_RS05605 (BAY21_05605) comYB 1046769..1047869 (+) 1101 WP_148148889.1 competence type IV pilus assembly protein ComGB Machinery gene
  BAY21_RS05610 (BAY21_05610) comYC 1047866..1048192 (+) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  BAY21_RS05615 (BAY21_05615) comYD 1048152..1048580 (+) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  BAY21_RS05620 (BAY21_05620) comGE 1048552..1048845 (+) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  BAY21_RS05625 (BAY21_05625) comYF 1048829..1049266 (+) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  BAY21_RS05630 (BAY21_05630) comGG 1049244..1049561 (+) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG -
  BAY21_RS05635 (BAY21_05635) comYH 1049606..1050562 (+) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  BAY21_RS05640 (BAY21_05640) - 1050618..1051811 (+) 1194 WP_022096898.1 acetate kinase -
  BAY21_RS05645 (BAY21_05645) - 1052060..1052257 (+) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41694.79 Da        Isoelectric Point: 10.0449

>NTDB_id=188254 BAY21_RS05605 WP_148148889.1 1046769..1047869(+) (comYB) [Streptococcus thermophilus strain CS8]
MPEKISKTIRLPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPSFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=188254 BAY21_RS05605 WP_148148889.1 1046769..1047869(+) (comYB) [Streptococcus thermophilus strain CS8]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCTACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTCTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGATATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.386

93.443

0.508
  comYB Streptococcus mutans UA159

54.386

93.443

0.508
  comYB Streptococcus gordonii str. Challis substr. CH1

50.877

93.443

0.475
  comGB/cglB Streptococcus mitis NCTC 12261

50.151

90.437

0.454
  comGB/cglB Streptococcus mitis SK321

49.394

90.164

0.445
  comGB/cglB Streptococcus pneumoniae Rx1

49.091

90.164

0.443
  comGB/cglB Streptococcus pneumoniae D39

49.091

90.164

0.443
  comGB/cglB Streptococcus pneumoniae R6

49.091

90.164

0.443
  comGB/cglB Streptococcus pneumoniae TIGR4

49.091

90.164

0.443
  comGB Lactococcus lactis subsp. cremoris KW2

45.758

90.164

0.413

Multiple sequence alignment