Detailed information NTG0188238

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: BAY21_RS03390
• Genome accession: NZ_CP016439
• Coordinates: 644625..645524 (-)
• Length: 299 a.a.
• NCBI ID: WP_011226854.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CS8
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 639625..650524

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BAY21_RS03350 (BAY21_03350)	-	639626..640141 (-)	516	WP_011226861.1	AmiS/UreI family transporter	-
BAY21_RS10925	-	640546..640917 (+)	372	WP_231108754.1	hypothetical protein	-
BAY21_RS10930	-	641141..641443 (+)	303	WP_011226859.1	hypothetical protein	-
BAY21_RS10935	-	641683..641967 (+)	285	WP_231108755.1	hypothetical protein	-
BAY21_RS03360 (BAY21_03360)	-	641935..642246 (-)	312	WP_011226857.1	DUF805 domain-containing protein	-
BAY21_RS03365 (BAY21_03365)	-	642354..642922 (-)	569	Protein_661	ATP-binding cassette domain-containing protein	-
BAY21_RS10940	-	643208..644449 (-)	1242	Protein_662	ABC transporter transmembrane domain-containing protein	-
BAY21_RS03390 (BAY21_03390)	comR	644625..645524 (-)	900	WP_011226854.1	helix-turn-helix domain-containing protein	Regulator
BAY21_RS03395 (BAY21_03395)	-	645719..646369 (-)	651	WP_011226853.1	phosphatase PAP2 family protein	-
BAY21_RS03400 (BAY21_03400)	-	646372..646929 (-)	558	WP_002949523.1	ECF transporter S component	-
BAY21_RS03405 (BAY21_03405)	-	647241..647780 (-)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
BAY21_RS03410 (BAY21_03410)	trkA	648039..649388 (+)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35317.79 Da
• Isoelectric Point: 5.1073

>NTDB_id=188238 BAY21_RS03390 WP_011226854.1 644625..645524(-) (comR) [Streptococcus thermophilus strain CS8]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLIIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=188238 BAY21_RS03390 WP_011226854.1 644625..645524(-) (comR) [Streptococcus thermophilus strain CS8]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAATCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421