Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   BWQ98_RS10195 Genome accession   NZ_CP019299
Coordinates   1872472..1872912 (-) Length   146 a.a.
NCBI ID   WP_050155274.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain HKU1-14     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1867472..1877912
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWQ98_RS10165 (BWQ98_10185) - 1867782..1868657 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  BWQ98_RS10170 (BWQ98_10190) pstC 1868775..1869638 (+) 864 WP_000165892.1 phosphate ABC transporter permease subunit PstC -
  BWQ98_RS10175 (BWQ98_10195) pstA 1869631..1870446 (+) 816 WP_050155273.1 phosphate ABC transporter permease PstA -
  BWQ98_RS10180 (BWQ98_10200) pstB 1870448..1871200 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  BWQ98_RS10185 (BWQ98_10205) phoU 1871215..1871865 (+) 651 WP_001245784.1 phosphate signaling complex protein PhoU -
  BWQ98_RS10190 (BWQ98_10210) - 1871927..1872358 (+) 432 Protein_1883 transposase -
  BWQ98_RS10195 (BWQ98_10215) comR 1872472..1872912 (-) 441 WP_050155274.1 helix-turn-helix transcriptional regulator Regulator
  BWQ98_RS10200 (BWQ98_10220) - 1873124..1874140 (+) 1017 WP_000415109.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  BWQ98_RS10205 (BWQ98_10225) galU 1874162..1875061 (+) 900 WP_000202230.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  BWQ98_RS10210 (BWQ98_10230) - 1875128..1875805 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  BWQ98_RS10215 (BWQ98_10235) - 1875789..1876328 (-) 540 WP_000834326.1 5-formyltetrahydrofolate cyclo-ligase -
  BWQ98_RS10220 (BWQ98_10240) - 1876340..1877470 (-) 1131 WP_000885107.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17646.40 Da        Isoelectric Point: 5.1703

>NTDB_id=179980 BWQ98_RS10195 WP_050155274.1 1872472..1872912(-) (comR) [Streptococcus pneumoniae strain HKU1-14]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYF
LMRTLTYEDETIAQKKESVFAKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 441 bp        

>NTDB_id=179980 BWQ98_RS10195 WP_050155274.1 1872472..1872912(-) (comR) [Streptococcus pneumoniae strain HKU1-14]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAACACTAACAAAGTTAAAATATATCGCTG
AACGTTTGGGGGTTGAAGATTACAAGTTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTC
TTGATGAGGACTCTTACATACGAAGATGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGCTAAGATTTTTGAAGAGTA
TTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAA
AATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(72-119)

Helix-turn-helix (HTH_3)

(8-59)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

53.333

82.192

0.438
  comR Streptococcus pyogenes MGAS315

51.667

82.192

0.425
  comR Streptococcus mutans UA159

51.667

82.192

0.425
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

52.727

75.342

0.397
  comR Streptococcus suis P1/7

47.458

80.822

0.384
  comR Streptococcus suis 05ZYH33

47.458

80.822

0.384
  comR Streptococcus suis D9

46.61

80.822

0.377