Detailed information NTG0178294

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: V471_RS04230
• Genome accession: NZ_CP015283
• Coordinates: 805229..807325 (+)
• Length: 698 a.a.
• NCBI ID: WP_049529069.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ATCC 25975
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 800229..812325

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V471_RS04200 (V471_04145)	-	800472..800981 (+)	510	WP_049529100.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
V471_RS04205 (V471_04150)	-	801290..801847 (+)	558	WP_049529098.1	ECF transporter S component	-
V471_RS04210 (V471_04155)	-	801850..802500 (+)	651	WP_045001950.1	phosphatase PAP2 family protein	-
V471_RS04215 (V471_04160)	-	802614..803000 (-)	387	WP_002886743.1	IS110 family transposase	-
V471_RS04220 (V471_04165)	-	803020..803781 (-)	762	WP_157108258.1	IS110 family transposase	-
V471_RS04225 (V471_04170)	comR	804155..805054 (+)	900	WP_084871132.1	helix-turn-helix transcriptional regulator	Regulator
V471_RS04230 (V471_04175)	comA	805229..807325 (+)	2097	WP_049529069.1	peptide cleavage/export ABC transporter	Regulator
V471_RS04235 (V471_04180)	-	807435..807767 (+)	333	WP_013990041.1	DUF805 domain-containing protein	-
V471_RS11410 (V471_04185)	-	807819..808442 (-)	624	WP_228382825.1	hypothetical protein	-
V471_RS04245 (V471_04190)	-	808795..809283 (+)	489	Protein_773	PDGLE domain-containing protein	-
V471_RS04250 (V471_04195)	-	809280..810059 (+)	780	WP_073687408.1	energy-coupling factor transporter transmembrane component T	-
V471_RS04255 (V471_04200)	-	810061..810777 (+)	717	WP_084871133.1	energy-coupling factor ABC transporter ATP-binding protein	-
V471_RS04260 (V471_04205)	-	810942..811790 (+)	849	WP_002883793.1	amino acid ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 698 a.a.
• Molecular weight: 78411.38 Da
• Isoelectric Point: 9.2748

>NTDB_id=178294 V471_RS04230 WP_049529069.1 805229..807325(+) (comA) [Streptococcus salivarius strain ATCC 25975]
MSKYPYISQIDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQENLSY
PFIAHVVKEGGLQHYYTVFGQIKGQLIIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGKSYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALIVQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKEFSFKQLAL
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAIGHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMGGGQIESDSPNFNPFQFI

Nucleotide

• Length: 2097 bp

>NTDB_id=178294 V471_RS04230 WP_049529069.1 805229..807325(+) (comA) [Streptococcus salivarius strain ATCC 25975]
ATGTCAAAATATCCATATATTTCACAGATTGATCAGCGTGATTGTGGTGTCGCTGCCTTAGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGGGAGTTGGCTCAGACTTCTCGTGAAGGCACTTCTGCGCTTGGTTTGGTTG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAACCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGACTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGCAGCTTAT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAGTTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAAAATCCTATACTAAATACAAAGAAGATGTACCTGGGCTTCTTTCATTTTTACCGATTTTGTTT
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTGTTAAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCTTACACTCTTCTGACCATGATTTCGCTAGGCCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGAAATTACTTGTCCATTGCTGTCATC
CTTCCTTATATTAAGCATGTCCTTTCCTTACCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACGTCACGTTT
TGGAGATGCCAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTGTACAAAATCAGTCACTTTTTGTGATGACTCTCACGGTAGTGCCTCTTTATGTTTTAATCATT
TTGGCATTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGAGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAAAGACGCTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCCAAGTGGCAATTAACGCAGGATGGTTTAAAGACAGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGTCATGGAAGGGCAACTATCTGCAGGTCAGTTGATTACTTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATTATTAATCTCCAATCCAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGATAAGGAAGAAAAAGGAAAACTTAAAGAGTTTTCTTTTAAACAACTTGCTCTT
AAAGGAGTCAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGGAAAACAACCTTAGCGAAAATGTTGTCAGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTGGCCATGCGGAGTTACGTCAAATGGTGACTTATGTTCCCCAGCAGACCTATGTG
TTTACAGGAACCATTTTAGAAAATCTGCTATTAGGATTTGAAGGAGAAGTTGACGAGAAAAAGCTCCTTAAGGTATGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGTTTTCAGACCCAAGTATCTGAGGATGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTGGCGATAGCGAGGGCCCTCTTGTCCAAGCAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTCCGTCAACATGTCAGCCGTGTAGTGACCATGGGGGGTGGTCAGATTGAGTCGGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (167-436)

• ABC transporter (ABC_tran) (494-640)

• Peptidase C39 family (Peptidase_C39) (3-140)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis SK321	53.69	98.997	0.532
comA	Streptococcus gordonii str. Challis substr. CH1	53.017	99.713	0.529
comA	Streptococcus mitis NCTC 12261	53.256	98.997	0.527
comA	Streptococcus pneumoniae Rx1	53.111	98.997	0.526
comA	Streptococcus pneumoniae D39	53.111	98.997	0.526
comA	Streptococcus pneumoniae R6	53.111	98.997	0.526
comA	Streptococcus pneumoniae TIGR4	52.967	98.997	0.524
comA/nlmT	Streptococcus mutans UA159	50.725	98.854	0.501