Detailed information NTG0177904

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: A4265_RS04650
• Genome accession: NZ_CP015238
• Coordinates: 903573..904409 (+)
• Length: 278 a.a.
• NCBI ID: WP_020905195.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NS53
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 898573..909409

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A4265_RS04620 (A4265_04335)	-	899124..899495 (+)	372	WP_063631894.1	hypothetical protein	-
A4265_RS04625 (A4265_04340)	-	899545..900456 (-)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
A4265_RS04630 (A4265_04345)	trhA	900573..901223 (-)	651	WP_063631895.1	PAQR family membrane homeostasis protein TrhA	-
A4265_RS04635 (A4265_04350)	-	901220..901660 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
A4265_RS04640 (A4265_04355)	ylqF	901879..902727 (+)	849	WP_020905193.1	ribosome biogenesis GTPase YlqF	-
A4265_RS04645 (A4265_04360)	-	902717..903508 (+)	792	WP_032464377.1	ribonuclease HII	-
A4265_RS04650 (A4265_04365)	dprA	903573..904409 (+)	837	WP_020905195.1	DNA-processing protein DprA	Machinery gene
A4265_RS04655 (A4265_04370)	topA	904516..906645 (+)	2130	WP_063631896.1	type I DNA topoisomerase	-
A4265_RS04660 (A4265_04375)	trmFO	906780..908126 (+)	1347	WP_063631897.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.00 Da
• Isoelectric Point: 9.2514

>NTDB_id=177904 A4265_RS04650 WP_020905195.1 903573..904409(+) (dprA) [Streptococcus pyogenes strain NS53]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=177904 A4265_RS04650 WP_020905195.1 903573..904409(+) (dprA) [Streptococcus pyogenes strain NS53]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367