Detailed information NTG0177458

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: A4H00_RS10740
• Genome accession: NZ_CP015196
• Coordinates: 2182191..2184344 (+)
• Length: 717 a.a.
• NCBI ID: WP_067090990.1
• Uniprot ID: -
• Organism: Streptococcus marmotae strain HTS5
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2177191..2189344

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A4H00_RS12240	-	2177977..2178249 (-)	273	Protein_2068	thioredoxin family protein	-
A4H00_RS12455	blpZ	2178367..2178669 (-)	303	WP_418080448.1	immunity protein BlpZ	-
A4H00_RS12305	-	2178870..2178992 (-)	123	WP_257721978.1	hypothetical protein	-
A4H00_RS10720	-	2179419..2179643 (-)	225	WP_067090978.1	bacteriocin	-
A4H00_RS10725	-	2179684..2180103 (-)	420	WP_067090981.1	hypothetical protein	-
A4H00_RS12245	-	2180279..2180374 (-)	96	WP_157771007.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
A4H00_RS11565	-	2180885..2181127 (+)	243	WP_237334201.1	transposase	-
A4H00_RS10730	-	2181257..2181616 (-)	360	WP_067090984.1	hypothetical protein	-
A4H00_RS10735	-	2181656..2181889 (-)	234	WP_067090986.1	bacteriocin-type signal sequence	-
A4H00_RS10740	comA/nlmT	2182191..2184344 (+)	2154	WP_067090990.1	peptide cleavage/export ABC transporter	Regulator
A4H00_RS10745	-	2184356..2185708 (+)	1353	WP_067090993.1	bacteriocin secretion accessory protein	-
A4H00_RS11570	-	2185811..2185969 (+)	159	WP_082815641.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
A4H00_RS10750	-	2186020..2187357 (-)	1338	WP_067090995.1	sensor histidine kinase	-
A4H00_RS10755	comE/blpR	2187371..2188108 (-)	738	WP_067090997.1	response regulator transcription factor	Regulator
A4H00_RS10760	-	2188110..2188451 (-)	342	WP_067090998.1	LytTR family DNA-binding domain-containing protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80657.54 Da
• Isoelectric Point: 7.3564

>NTDB_id=177458 A4H00_RS10740 WP_067090990.1 2182191..2184344(+) (comA/nlmT) [Streptococcus marmotae strain HTS5]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSNYSLAHLRELAKTNKEGTTALGIVKAANEMGFETRAIQADMTLFDMEDV
PYPFIVHVNKDGRLQHYYVVYQAKKDYLIIGDPDPTVKITKMTKERFASEWTGVAIFLAPEASYKPHKDKKNGLLSFLPL
IFKQSSLIFYIVLASLLVTLINISGSYYIQGILDEYIPNQMKSTLGIISIGLIVTYILQQIMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILIIVGSVLLVQNTNLFLLSLISVPIYIA
IIFIFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEERRYQKIDSEFVDYLDKSFRLSKYSILQGTLKQGAQL
ILNTGILWFGARLVMDNSISIGQLITFNTLLSYFTHPLENIINLQTKLQSAKVANNRLNEVYLVESEFSDSQTLTDSQFL
SGDIQFEDLSYKYGFGRDTLSDINLTIKKGDKVSLVGISGSGKTTLAKMIVNFFEPYKGRITINNNDLKMVDKKVLRKHI
NYLPQQAYIFSGSVLENLTLGANQMIRQEDILRACEIAEIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAS
VLILDEATSGLDVLTEKKVIDNLMTMTDKTIIFVAHRLSISERTNQVIVLDQGKIIETGSHQELMAKQGFYHHLFSK

Nucleotide

• Length: 2154 bp

>NTDB_id=177458 A4H00_RS10740 WP_067090990.1 2182191..2184344(+) (comA/nlmT) [Streptococcus marmotae strain HTS5]
ATGACATCCTACAAACGAACATTTGTCCCACAGATTGATGCTAGGGACTGTGGTGTCGCTGCGTTAGCTTCCATCGCAAA
ATTCTACGGTTCGAACTATTCTCTAGCCCACTTGAGAGAGTTAGCCAAAACGAATAAGGAAGGGACGACTGCTCTTGGGA
TTGTAAAAGCCGCTAATGAGATGGGATTTGAAACAAGGGCTATTCAAGCAGATATGACCCTTTTTGATATGGAAGATGTA
CCTTATCCCTTTATCGTCCATGTCAATAAGGATGGGAGACTTCAACACTACTATGTCGTCTATCAAGCAAAAAAAGACTA
TCTGATCATCGGTGACCCTGATCCGACAGTCAAAATCACGAAGATGACTAAGGAACGCTTTGCCTCCGAATGGACAGGGG
TTGCCATTTTTCTAGCCCCTGAAGCAAGCTATAAGCCGCATAAAGATAAAAAGAATGGACTATTGAGTTTTCTTCCTTTA
ATTTTTAAACAGAGCTCTCTTATCTTCTATATTGTACTAGCAAGTCTCCTAGTCACTCTCATCAATATTAGCGGTTCTTA
CTATATTCAAGGAATTTTAGATGAATATATTCCTAATCAGATGAAGTCCACTTTAGGAATTATCTCTATTGGCTTGATTG
TCACCTATATTCTCCAGCAGATAATGAGTTTCTCTCGAGACTATCTTCTCACTGTATTGAGTCAGAGACTAAGTATTGAT
GTCATTCTGTCTTATATCCGCCACATCTTTGAATTACCCATGTCCTTTTTTGCCACACGGCGGACAGGGGAAGTAATCTC
CCGCTTTACAGATGCCAACTCCATCATTGACGCTTTAGCATCCACCATTCTATCCCTCTTTCTGGATGTCTCTATCCTCA
TCATCGTTGGTAGTGTCCTTCTGGTACAAAATACCAATCTTTTTTTACTATCACTGATTTCCGTCCCTATCTACATTGCC
ATTATTTTCATCTTTATGAAACCATTTGAAAAGATGAATCATGATGTCATGCAAAGCAATTCCATGGTCAGCTCCGCTAT
TATTGAAGATATTAACGGTATCGAAACCATCAAGTCATTAACTAGCGAAGAAAGGCGCTACCAGAAAATTGACAGCGAGT
TCGTTGACTATCTAGATAAGTCCTTTAGATTAAGTAAGTACTCTATCCTACAAGGAACTCTAAAACAAGGAGCTCAATTA
ATCCTTAATACGGGTATTCTCTGGTTTGGAGCTAGATTAGTCATGGATAACTCGATTTCTATTGGTCAACTAATTACCTT
CAATACACTGCTCAGCTATTTTACCCATCCTCTGGAAAATATCATCAACCTTCAAACAAAATTACAATCTGCAAAAGTAG
CTAATAATCGTCTAAATGAAGTTTACTTGGTTGAATCAGAATTTAGCGATAGTCAGACACTAACAGATAGCCAATTTCTT
TCTGGTGATATTCAGTTTGAAGACCTTTCCTACAAGTATGGTTTTGGTCGTGACACCTTATCAGACATCAATCTGACAAT
CAAAAAAGGCGACAAGGTGAGTCTCGTAGGGATTAGTGGTTCAGGAAAGACGACTTTAGCTAAAATGATTGTCAACTTCT
TTGAACCCTACAAAGGACGCATCACCATTAACAATAACGACCTCAAAATGGTGGATAAAAAAGTATTGCGAAAACATATC
AACTACCTCCCTCAACAAGCCTATATCTTTAGCGGTTCTGTTTTAGAGAATTTGACCTTGGGTGCTAATCAGATGATTCG
TCAAGAAGATATTTTAAGGGCTTGTGAAATTGCAGAGATCCGCCATGACATCGAACAGATGCCTATGGGCTATCAAACAG
AACTCTCTGACGGAGCAGGTCTGTCCGGTGGTCAAAAACAACGGATTGCCCTAGCCAGGGCTCTTCTCACCAAAGCTTCT
GTTCTCATACTCGATGAAGCGACAAGCGGTCTTGATGTCCTGACAGAAAAAAAGGTGATTGATAACCTGATGACGATGAC
TGATAAAACCATTATTTTTGTAGCTCATCGACTTAGCATTTCTGAGCGAACCAATCAGGTCATTGTCCTTGACCAAGGAA
AAATTATTGAGACTGGCTCTCATCAGGAACTAATGGCTAAGCAAGGCTTCTACCATCATTTATTTAGTAAGTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (168-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	73.147	99.721	0.729
comA	Streptococcus mitis NCTC 12261	67.651	99.163	0.671
comA	Streptococcus mitis SK321	67.089	99.163	0.665
comA	Streptococcus pneumoniae Rx1	66.948	99.163	0.664
comA	Streptococcus pneumoniae D39	66.948	99.163	0.664
comA	Streptococcus pneumoniae R6	66.948	99.163	0.664
comA	Streptococcus pneumoniae TIGR4	66.667	99.163	0.661
comA	Streptococcus gordonii str. Challis substr. CH1	65.594	99.721	0.654