Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   A4H00_RS10755 Genome accession   NZ_CP015196
Coordinates   2187371..2188108 (-) Length   245 a.a.
NCBI ID   WP_067090997.1    Uniprot ID   -
Organism   Streptococcus marmotae strain HTS5     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2182371..2193108
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4H00_RS10745 - 2184356..2185708 (+) 1353 WP_067090993.1 bacteriocin secretion accessory protein -
  A4H00_RS11570 - 2185811..2185969 (+) 159 WP_082815641.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  A4H00_RS10750 - 2186020..2187357 (-) 1338 WP_067090995.1 sensor histidine kinase -
  A4H00_RS10755 comE/blpR 2187371..2188108 (-) 738 WP_067090997.1 response regulator transcription factor Regulator
  A4H00_RS10760 - 2188110..2188451 (-) 342 WP_067090998.1 LytTR family DNA-binding domain-containing protein -
  A4H00_RS11700 - 2189057..2189420 (-) 364 Protein_2083 helical hairpin domain-containing protein -
  A4H00_RS11930 - 2189966..2190094 (-) 129 Protein_2084 transposase -
  A4H00_RS11705 - 2190136..2190219 (-) 84 Protein_2085 TIGR01457 family HAD-type hydrolase -
  A4H00_RS10770 - 2190229..2190849 (-) 621 WP_067090999.1 NUDIX hydrolase N-terminal domain-containing protein -
  A4H00_RS10775 - 2190833..2191575 (-) 743 Protein_2087 acyl-ACP thioesterase domain-containing protein -
  A4H00_RS10780 hemW 2191575..2192714 (-) 1140 WP_067091626.1 radical SAM family heme chaperone HemW -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28585.74 Da        Isoelectric Point: 6.3035

>NTDB_id=177459 A4H00_RS10755 WP_067090997.1 2187371..2188108(-) (comE/blpR) [Streptococcus marmotae strain HTS5]
MDIFVLEDDFRQQTRLEQVIETLLEKHQIEPTYFDIFGKPDQLIHSIHQRGSHQVFFLDIEIKSEELKGLQVAKQIRAID
PYAIIVFVTTHSEFMPLSFRYQVSALDYIDKELSASEFESRIEAALLYAKSKEGKTIADDSFYFKSKYAQVQYPFEDVYY
IETSPLPHRVILYTKTDRMEFTASLSDILKQEKRLVQCHRSFAINPKNVVKVDRQAKLLYFPNGASCLIARQKMEGTLSS
IEQLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=177459 A4H00_RS10755 WP_067090997.1 2187371..2188108(-) (comE/blpR) [Streptococcus marmotae strain HTS5]
ATGGATATATTTGTATTGGAAGATGATTTTAGGCAACAAACCCGACTTGAGCAAGTGATTGAAACATTACTAGAGAAACA
TCAGATTGAGCCAACGTATTTTGATATTTTTGGAAAGCCTGATCAGTTGATTCATTCCATTCACCAGAGAGGTTCGCATC
AGGTATTTTTTTTGGATATTGAGATAAAGTCAGAAGAACTCAAAGGTCTTCAAGTTGCTAAACAGATTCGAGCAATTGAT
CCCTATGCAATTATTGTGTTTGTAACAACTCACTCTGAGTTTATGCCGTTATCATTTCGTTATCAAGTATCGGCATTGGA
TTATATCGATAAAGAATTATCTGCTAGTGAATTTGAATCTCGCATTGAAGCAGCTCTACTCTATGCAAAAAGTAAGGAGG
GTAAAACAATAGCTGATGATTCCTTTTATTTCAAATCGAAATATGCTCAGGTTCAATATCCTTTTGAAGACGTCTATTAT
ATAGAGACTTCTCCACTTCCTCATCGAGTTATTCTCTATACCAAGACTGACCGAATGGAATTTACCGCGAGCTTATCAGA
TATTCTAAAACAGGAGAAGAGATTAGTACAATGTCATCGTTCATTTGCTATCAATCCTAAGAATGTTGTTAAAGTGGACA
GGCAAGCTAAACTTCTCTATTTTCCTAATGGAGCAAGTTGTTTGATTGCACGACAAAAGATGGAGGGGACCTTGTCATCG
ATTGAGCAGCTACATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.043

95.918

0.518
  comE/comE1 Streptococcus equinus JB1

42.739

98.367

0.42
  comE/comE2 Streptococcus equinus JB1

38.934

99.592

0.388

Multiple sequence alignment