Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   A4G25_RS01645 Genome accession   NZ_CP015114
Coordinates   314214..314540 (+) Length   108 a.a.
NCBI ID   WP_047130996.1    Uniprot ID   A0A143P863
Organism   Staphylococcus condimenti strain DSM 11674     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 309214..319540
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4G25_RS01615 (A4G25_01615) - 309967..310167 (+) 201 WP_047130990.1 YqgQ family protein -
  A4G25_RS01620 (A4G25_01620) - 310167..311153 (+) 987 WP_047130991.1 ROK family glucokinase -
  A4G25_RS01625 (A4G25_01625) - 311153..311482 (+) 330 WP_047130992.1 MTH1187 family thiamine-binding protein -
  A4G25_RS01630 (A4G25_01630) - 311482..312105 (+) 624 WP_047130993.1 MBL fold metallo-hydrolase -
  A4G25_RS01635 (A4G25_01635) comGA 312177..313151 (+) 975 WP_047130994.1 competence type IV pilus ATPase ComGA Machinery gene
  A4G25_RS01640 (A4G25_01640) comGB 313123..314196 (+) 1074 WP_047130995.1 competence type IV pilus assembly protein ComGB -
  A4G25_RS01645 (A4G25_01645) comGC 314214..314540 (+) 327 WP_047130996.1 competence type IV pilus major pilin ComGC Machinery gene
  A4G25_RS01650 (A4G25_01650) - 314560..314973 (+) 414 WP_232011920.1 prepilin-type cleavage/methylation domain-containing protein -
  A4G25_RS13035 (A4G25_01655) - 314954..315247 (+) 294 WP_047130998.1 hypothetical protein -
  A4G25_RS01660 (A4G25_01660) - 315276..315665 (+) 390 WP_257722037.1 ComGF family competence protein -
  A4G25_RS01665 (A4G25_01665) - 315830..316369 (+) 540 WP_152650907.1 shikimate kinase -
  A4G25_RS01670 (A4G25_01670) gcvT 316561..317655 (+) 1095 WP_047131000.1 glycine cleavage system aminomethyltransferase GcvT -
  A4G25_RS01675 (A4G25_01675) gcvPA 317676..319022 (+) 1347 WP_047131001.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12114.29 Da        Isoelectric Point: 9.7598

>NTDB_id=176762 A4G25_RS01645 WP_047130996.1 314214..314540(+) (comGC) [Staphylococcus condimenti strain DSM 11674]
MKKYYLLFKNKNLKAFTLLEMLLVLLVISVLLILIIPNIAKQSEHVQSTGCEAQQKMVNSQIEAFTLKNNQKPNSIDELV
TQGYLKEGQKKCKSGESITIKNGEASIS

Nucleotide


Download         Length: 327 bp        

>NTDB_id=176762 A4G25_RS01645 WP_047130996.1 314214..314540(+) (comGC) [Staphylococcus condimenti strain DSM 11674]
ATGAAAAAATATTACTTATTATTTAAAAATAAAAACTTAAAAGCTTTTACATTGTTAGAAATGTTGCTCGTATTGTTGGT
TATCAGTGTATTATTAATTTTGATTATACCTAACATTGCTAAGCAATCTGAACATGTTCAATCTACAGGTTGTGAGGCAC
AGCAAAAAATGGTGAATAGTCAAATAGAAGCCTTTACACTTAAAAATAACCAAAAGCCCAATTCTATCGATGAACTTGTA
ACACAAGGTTATCTAAAGGAAGGGCAAAAGAAATGTAAATCTGGAGAAAGTATAACAATTAAAAATGGTGAAGCTTCAAT
TAGCTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-35)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A143P863

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus MW2

70.526

87.963

0.62
  comGC Staphylococcus aureus N315

70.526

87.963

0.62
  comGC/cglC Streptococcus mitis SK321

43.396

98.148

0.426
  comGC/cglC Streptococcus pneumoniae R6

42.453

98.148

0.417
  comGC/cglC Streptococcus pneumoniae D39

42.453

98.148

0.417
  comGC/cglC Streptococcus pneumoniae TIGR4

42.453

98.148

0.417
  comGC/cglC Streptococcus pneumoniae Rx1

42.453

98.148

0.417
  comGC/cglC Streptococcus mitis NCTC 12261

45.652

85.185

0.389
  comGC Bacillus subtilis subsp. subtilis str. 168

41.667

88.889

0.37

Multiple sequence alignment