Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   BUM80_RS08005 Genome accession   NZ_CP018838
Coordinates   1455793..1456233 (-) Length   146 a.a.
NCBI ID   WP_001206580.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 11A     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1450793..1461233
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUM80_RS07975 (BUM80_08190) - 1451102..1451977 (+) 876 WP_157807954.1 substrate-binding domain-containing protein -
  BUM80_RS07980 (BUM80_08195) pstC 1452095..1452958 (+) 864 WP_000595182.1 phosphate ABC transporter permease subunit PstC -
  BUM80_RS07985 (BUM80_08200) pstA 1452951..1453766 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  BUM80_RS07990 (BUM80_08205) pstB 1453768..1454520 (+) 753 WP_000536447.1 phosphate ABC transporter ATP-binding protein PstB -
  BUM80_RS07995 (BUM80_08210) phoU 1454535..1455185 (+) 651 WP_001245789.1 phosphate signaling complex protein PhoU -
  BUM80_RS08000 (BUM80_08215) - 1455226..1455678 (+) 453 Protein_1466 transposase -
  BUM80_RS08005 (BUM80_08220) comR 1455793..1456233 (-) 441 WP_001206580.1 helix-turn-helix transcriptional regulator Regulator
  BUM80_RS08010 (BUM80_08225) - 1456445..1457461 (+) 1017 WP_000415108.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  BUM80_RS08015 (BUM80_08230) galU 1457483..1458382 (+) 900 WP_000202232.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  BUM80_RS08020 (BUM80_08235) - 1458449..1459126 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  BUM80_RS08025 (BUM80_08240) - 1459110..1459649 (-) 540 WP_000834344.1 5-formyltetrahydrofolate cyclo-ligase -
  BUM80_RS08030 (BUM80_08245) - 1459661..1460791 (-) 1131 WP_000885068.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17684.45 Da        Isoelectric Point: 4.9958

>NTDB_id=176380 BUM80_RS08005 WP_001206580.1 1455793..1456233(-) (comR) [Streptococcus pneumoniae strain 11A]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYF
LMRTPTYEDETIAQKKESVFAKIFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 441 bp        

>NTDB_id=176380 BUM80_RS08005 WP_001206580.1 1455793..1456233(-) (comR) [Streptococcus pneumoniae strain 11A]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTG
AACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTC
TTGATGAGGACTCCTACATACGAAGATGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGCTAAGATTTTTGAAGAGTA
TTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCCCAAATTATTCATATCTAGCACTAGCGAACTACACAGTTCAAA
AATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(72-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

54.167

82.192

0.445
  comR Streptococcus pyogenes MGAS315

52.5

82.192

0.432
  comR Streptococcus mutans UA159

50.833

82.192

0.418
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

52.727

75.342

0.397
  comR Streptococcus suis P1/7

46.61

80.822

0.377
  comR Streptococcus suis 05ZYH33

46.61

80.822

0.377
  comR Streptococcus suis D9

45.763

80.822

0.37