Detailed information NTG0174493

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: A2G56_RS07250
• Genome accession: NZ_CP014835
• Coordinates: 1571284..1572501 (-)
• Length: 405 a.a.
• NCBI ID: WP_062710855.1
• Uniprot ID: -
• Organism: Streptococcus halotolerans strain HTS9
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1566284..1577501

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2G56_RS07225	-	1566825..1567196 (-)	372	WP_082785127.1	helix-turn-helix domain-containing protein	-
A2G56_RS07230	-	1567317..1567520 (-)	204	WP_062710843.1	DUF951 domain-containing protein	-
A2G56_RS07235	dnaN	1567604..1568740 (-)	1137	WP_062710850.1	DNA polymerase III subunit beta	-
A2G56_RS07240	dnaA	1568894..1570261 (-)	1368	WP_062710851.1	chromosomal replication initiator protein DnaA	-
A2G56_RS07245	spo0J	1570463..1571230 (-)	768	WP_062710852.1	ParB/RepB/Spo0J family partition protein	Regulator
A2G56_RS07250	htrA	1571284..1572501 (-)	1218	WP_062710855.1	S1C family serine protease	Regulator
A2G56_RS07255	rlmH	1572732..1573211 (+)	480	WP_062710858.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
A2G56_RS07270	-	1573628..1573831 (-)	204	WP_062710861.1	ISL3 family transposase	-

Sequence

Protein

• Length: 405 a.a.
• Molecular weight: 43007.25 Da
• Isoelectric Point: 6.2924

>NTDB_id=174493 A2G56_RS07250 WP_062710855.1 1571284..1572501(-) (htrA) [Streptococcus halotolerans strain HTS9]
MTNKSTNSFKRTLTTIIVALISGLLGAFMFFYFSENLIPSSSNSHQKTRTSNVVYNNTTDTTKAAKKVQDAVVSVINYRK
KSNSSLNDLYSQVFGNDQEKNSSDELSVYSEGSGVIYKKQDGSAYVVTNNHVIDGAESIEIMLSDGTKVVGKLVGSDTYS
DLAVVKISGKKVSTVAEFANSDKLNVGETAIAMGSPLGTEYANTVTQGIVSSLSRTVTLKNDEGETISTNAIQTDAAINP
GNSGGALINIEGQVIGINSSKISSTSTAGEAVEGMGFAIPANDVLKIINQLEKNGQVTRPALGISMANLSDLSTSVISEL
KIPESVTAGIVVASVQDNMPASGKLKRYDVITKINNKDVTSTSDLQSILYGHDIGDTIKVTYYRGKDKQTAAIKLSKSTK
DLENN

Nucleotide

• Length: 1218 bp

>NTDB_id=174493 A2G56_RS07250 WP_062710855.1 1571284..1572501(-) (htrA) [Streptococcus halotolerans strain HTS9]
TTGACAAACAAATCAACCAATAGCTTTAAACGAACACTGACAACCATTATAGTTGCTCTGATTTCTGGTTTACTAGGAGC
CTTTATGTTTTTTTATTTCTCAGAAAACTTAATACCATCTTCAAGTAATTCCCACCAAAAAACTAGAACTAGCAATGTTG
TCTACAATAATACAACCGACACAACCAAAGCAGCTAAAAAAGTACAAGACGCTGTCGTTTCCGTTATCAACTATCGAAAA
AAATCCAATTCCTCTTTAAATGACCTCTATTCACAAGTCTTTGGCAATGACCAAGAAAAAAATTCCAGTGATGAACTTAG
CGTGTACAGTGAGGGGTCTGGGGTTATCTATAAAAAACAAGATGGTTCAGCTTATGTTGTTACTAATAACCACGTTATTG
ATGGAGCTGAAAGTATCGAAATCATGCTTTCTGATGGTACTAAAGTTGTCGGAAAGTTAGTTGGTTCCGATACTTACTCT
GACCTAGCTGTTGTCAAAATTTCAGGTAAAAAGGTATCAACTGTTGCCGAATTTGCTAATTCAGATAAACTTAATGTCGG
CGAAACAGCCATCGCTATGGGAAGCCCACTCGGTACCGAGTATGCTAACACTGTTACTCAAGGGATTGTTTCCAGTCTAA
GTCGTACGGTGACCCTTAAAAATGATGAAGGTGAGACCATTTCAACCAATGCCATTCAAACAGATGCTGCTATCAACCCT
GGTAACTCTGGAGGAGCGCTCATTAACATTGAAGGCCAAGTTATTGGAATCAATTCAAGTAAAATTTCTTCAACTTCAAC
AGCTGGCGAAGCCGTAGAAGGAATGGGATTTGCTATTCCAGCTAATGATGTACTAAAAATTATCAATCAGTTAGAAAAGA
ATGGCCAAGTAACACGACCTGCTCTTGGTATTTCTATGGCTAATTTGAGCGATCTCTCAACCAGTGTAATCTCAGAACTA
AAAATCCCTGAAAGTGTCACAGCTGGTATTGTTGTCGCTTCAGTTCAAGATAATATGCCCGCTTCAGGTAAACTCAAACG
CTACGATGTTATTACTAAAATCAATAACAAAGACGTCACATCAACAAGTGATCTCCAAAGCATTCTTTATGGACATGATA
TTGGAGATACTATCAAAGTGACTTACTACCGTGGTAAAGATAAACAAACAGCCGCTATTAAATTAAGCAAGTCAACCAAA
GACTTAGAAAATAACTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (300-395)

• Trypsin-like peptidase domain (Trypsin_2) (112-257)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	62.899	100	0.632
htrA	Streptococcus pneumoniae Rx1	59.241	97.531	0.578
htrA	Streptococcus pneumoniae D39	59.241	97.531	0.578
htrA	Streptococcus pneumoniae R6	59.241	97.531	0.578
htrA	Streptococcus pneumoniae TIGR4	59.241	97.531	0.578
htrA	Streptococcus mitis NCTC 12261	59.847	96.543	0.578
htrA	Streptococcus gordonii str. Challis substr. CH1	57.816	99.506	0.575