Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   A2G56_RS04970 Genome accession   NZ_CP014835
Coordinates   1133557..1135464 (-) Length   635 a.a.
NCBI ID   WP_062709877.1    Uniprot ID   -
Organism   Streptococcus halotolerans strain HTS9     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1128557..1140464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A2G56_RS04945 - 1129263..1129622 (-) 360 WP_062709865.1 S1 RNA-binding domain-containing protein -
  A2G56_RS04950 - 1129622..1131022 (-) 1401 WP_062709867.1 Cof-type HAD-IIB family hydrolase -
  A2G56_RS04955 - 1131071..1131709 (-) 639 WP_062709869.1 response regulator transcription factor -
  A2G56_RS04960 - 1131702..1132700 (-) 999 WP_062709871.1 sensor histidine kinase -
  A2G56_RS04965 liaF 1132697..1133395 (-) 699 WP_062709874.1 cell wall-active antibiotics response protein LiaF -
  A2G56_RS04970 pknB 1133557..1135464 (-) 1908 WP_062709877.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  A2G56_RS04975 - 1135464..1136201 (-) 738 WP_062709880.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  A2G56_RS04980 rsmB 1136251..1137573 (-) 1323 WP_062709884.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  A2G56_RS04985 fmt 1137566..1138504 (-) 939 WP_062709887.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 635 a.a.        Molecular weight: 68860.32 Da        Isoelectric Point: 6.4491

>NTDB_id=174468 A2G56_RS04970 WP_062709877.1 1133557..1135464(-) (pknB) [Streptococcus halotolerans strain HTS9]
MIQIGKLFAGRYRILKSIGRGGMADVYLAHDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLAMEYVNGPDLKKYIQDHAPLSNAETVRIMSEVLSAMQLAHQKGIVHRDLKPQNVLLTKDGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTCHIPFDGDSAVTIALQHFQKPLPSIIFENRNVP
QALENVVIKATAKKLGDRYVSTTDMYQDLGTALDPRRSRERKLVFQDSTDTKTLPKIEPAPVKETPKPVAASEPVKGAAT
KETSKTVNSAPNHTTNKKSKRPLWQRLFRFFILIVVILAAGFAYFVMSSSNDSVVVPDVSGQTIKQAQSTLEEAGLTVGS
VARKESETVKEGRVISTSPKAGATKKEGSEIKLTVSKGTKRFDMTDYTRMTYRDAVKDLTENYGLSKKQIIKKEVSSDEH
KPGEIINQTPEAGESFDPSGNDKITFEVATSATVTVPALVGYSYADAKNTLLDLGFKSSQIQTDSDRPSSSSTVYAQYPY
AGTSIELSTGEGVTLYLTNPDSSASSSSSASSSGADTSMTSQPESSSSNSSSSSSHSSTDTSEGNSQTESSSDSP

Nucleotide


Download         Length: 1908 bp        

>NTDB_id=174468 A2G56_RS04970 WP_062709877.1 1133557..1135464(-) (pknB) [Streptococcus halotolerans strain HTS9]
ATGATCCAAATCGGCAAATTATTTGCTGGGCGTTATCGTATTCTTAAATCCATTGGTCGTGGTGGTATGGCTGATGTCTA
TTTGGCACATGACCTGATTTTAGATAATGAAGAAGTAGCCATTAAGGTGCTTCGAACCAATTATCAAACAGACCAGATTG
CTGTTGCTCGTTTCCAGCGAGAAGCACGTGCGATGGCCGAATTGAGTCATCCTAATATTGTTGCAATCAGAGATATTGGC
GAAGAAGATGGTCAACAATTTCTTGCAATGGAGTACGTTAACGGTCCAGATTTAAAAAAATATATTCAAGATCACGCTCC
GCTATCCAATGCTGAAACAGTTCGTATTATGAGTGAGGTTCTATCTGCCATGCAGTTAGCCCATCAAAAAGGAATTGTTC
ACCGCGATTTGAAACCACAGAATGTTCTGTTAACAAAAGATGGTGTGGCTAAGGTTACCGACTTTGGTATTGCGGTTGCT
TTTGCAGAAACCAGTCTGACCCAAACGAATTCTATGTTGGGGAGTGTGCACTACCTATCACCGGAACAAGCTCGTGGGTC
AAAGGCAACGATTCAAAGTGATATCTATGCCATGGGAATTATGCTGTTTGAGATGCTTACTTGCCACATTCCTTTCGATG
GCGATAGCGCTGTAACCATTGCTCTTCAGCACTTCCAAAAACCGCTGCCTTCGATTATTTTTGAAAATCGAAACGTTCCG
CAAGCTTTGGAAAACGTTGTGATTAAGGCGACTGCTAAAAAACTAGGAGACCGTTATGTCTCCACAACAGACATGTATCA
AGACTTAGGGACCGCTCTCGATCCTCGTAGATCGCGTGAACGAAAGCTAGTTTTCCAAGATTCGACGGATACTAAGACCT
TACCTAAGATTGAACCGGCTCCTGTTAAAGAGACTCCTAAACCAGTTGCAGCATCAGAGCCAGTCAAGGGAGCGGCCACC
AAAGAAACGTCTAAAACAGTTAACTCTGCACCCAACCATACGACAAATAAAAAGTCCAAAAGACCACTTTGGCAACGCTT
ATTCAGGTTCTTTATTTTAATTGTTGTTATATTGGCGGCTGGCTTTGCTTACTTTGTTATGTCAAGTAGCAATGATAGTG
TTGTAGTACCAGATGTCTCTGGTCAAACTATTAAACAAGCGCAATCAACTCTTGAAGAGGCTGGTTTAACAGTTGGCAGT
GTGGCGCGTAAAGAAAGTGAAACAGTCAAAGAAGGGCGAGTTATTTCTACCAGTCCTAAAGCAGGAGCTACTAAAAAAGA
AGGTAGTGAAATTAAGTTAACAGTGTCAAAAGGGACAAAGCGTTTCGATATGACTGATTATACTAGAATGACCTATAGAG
ATGCTGTTAAAGATTTGACGGAAAATTATGGACTTTCGAAGAAGCAAATCATCAAAAAAGAAGTCTCAAGTGACGAACAT
AAACCTGGCGAAATCATTAACCAAACGCCAGAAGCTGGCGAAAGTTTTGATCCTTCTGGAAATGATAAAATCACCTTTGA
GGTAGCAACTTCAGCAACTGTAACCGTTCCAGCTTTGGTTGGTTACAGTTATGCAGATGCTAAAAATACTCTGTTAGATT
TAGGTTTTAAATCGTCACAGATTCAGACTGATTCGGATCGACCGTCTTCTTCATCAACTGTTTATGCTCAATATCCATAT
GCGGGTACTTCAATTGAACTTTCTACTGGCGAAGGTGTGACACTCTATTTGACCAACCCGGACTCATCAGCATCTAGCAG
CAGTAGCGCATCATCAAGCGGTGCTGATACTAGCATGACAAGCCAACCAGAGTCAAGTAGTTCTAACAGTTCATCAAGTT
CCAGTCATTCTTCGACGGATACTTCCGAGGGTAACAGTCAAACAGAGTCGTCTAGCGATTCTCCTTGA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(444-509)

PASTA domain (PASTA)

(374-437)

PASTA domain (PASTA)

(514-578)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

62.393

92.126

0.575
  stkP/pknB Streptococcus salivarius strain HSISS4

63.021

90.709

0.572
  stkP Streptococcus pneumoniae TIGR4

51.736

95.276

0.493
  stkP Streptococcus pneumoniae D39

51.57

95.276

0.491
  stkP Streptococcus pneumoniae R6

51.57

95.276

0.491
  stkP Streptococcus pneumoniae Rx1

51.405

95.276

0.49

Multiple sequence alignment