Detailed information NTG0173732

Bioinformatically predicted

Overview

• Name: comR/comR1
• Type: Regulator
• Locus tag: BSR20_RS03710
• Genome accession: NZ_CP018189
• Coordinates: 849890..850810 (-)
• Length: 306 a.a.
• NCBI ID: WP_014632992.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ICDC3
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 844890..855810

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR20_RS03680 (BSR20_03715)	-	846097..846293 (-)	197	Protein_669	transposase	-
BSR20_RS03685 (BSR20_03720)	-	846326..846838 (+)	513	WP_156209645.1	NAD(P)H-dependent oxidoreductase	-
BSR20_RS03690 (BSR20_03725)	-	847016..847114 (+)	99	Protein_671	XRE family transcriptional regulator	-
BSR20_RS03695 (BSR20_03730)	comR	847202..848113 (-)	912	WP_037600678.1	helix-turn-helix domain-containing protein	Regulator
BSR20_RS03700 (BSR20_03735)	-	848269..848988 (-)	720	WP_004182331.1	ABC transporter permease	-
BSR20_RS03705 (BSR20_03740)	-	848981..849817 (-)	837	WP_037600683.1	ABC transporter ATP-binding protein	-
BSR20_RS03710 (BSR20_03745)	comR/comR1	849890..850810 (-)	921	WP_014632992.1	helix-turn-helix domain-containing protein	Regulator
BSR20_RS03715 (BSR20_03750)	-	851028..851549 (+)	522	WP_229056628.1	RDD family protein	-
BSR20_RS03720 (BSR20_03755)	-	851610..852053 (+)	444	WP_014634653.1	8-oxo-dGTP diphosphatase	-
BSR20_RS03725 (BSR20_03760)	-	852240..853589 (+)	1350	WP_014634652.1	DUF262 domain-containing protein	-
BSR20_RS03730 (BSR20_03765)	-	853594..855426 (+)	1833	WP_014634651.1	GmrSD restriction endonuclease domain-containing protein	-

Sequence

Protein

• Length: 306 a.a.
• Molecular weight: 36131.36 Da
• Isoelectric Point: 4.4824

>NTDB_id=173732 BSR20_RS03710 WP_014632992.1 849890..850810(-) (comR/comR1) [Streptococcus salivarius strain ICDC3]
MSEDIKIEIGKRIREERERQGLTREQVCDTEEELTVKQLMRIELGRSLPTIVKLQYISDKLSVSLNYLLGETKLDIPEDY
YKAKYKLMKSPVYGDSERIKKKLKDIEELYDNYIDVLPEDELLAIDLIERTLNFMISEEESLIESVFEDYLVQALKKETY
SLNDLLLISYYAFRCQDYDYDKERIEKFRRKLINQELQGEELFNVELIGALSAIAGIYVMHHDYKEMKSVVDKMYVLIDK
TLQQAYKPAVLVFEAKYYLFYENNRDKATELYNTATVLAEAFGDQVFIKNLKMEMENDLDTSNESK

Nucleotide

• Length: 921 bp

>NTDB_id=173732 BSR20_RS03710 WP_014632992.1 849890..850810(-) (comR/comR1) [Streptococcus salivarius strain ICDC3]
ATGTCAGAAGATATTAAAATCGAGATTGGAAAAAGAATTCGTGAAGAACGTGAACGTCAAGGGTTAACACGTGAGCAAGT
TTGTGATACCGAAGAAGAATTAACCGTCAAACAACTGATGAGAATTGAGCTTGGGCGTTCTTTACCAACTATTGTCAAAC
TTCAATACATCAGTGATAAATTGAGTGTTTCCCTCAACTATTTGTTAGGTGAAACAAAACTAGACATTCCTGAAGACTAT
TACAAGGCTAAATATAAACTTATGAAGTCTCCTGTCTATGGTGACTCGGAACGTATCAAGAAAAAGCTAAAAGATATTGA
GGAACTCTACGACAACTATATTGATGTGCTACCAGAGGACGAGCTTTTAGCTATTGATCTCATTGAAAGAACCCTGAATT
TTATGATTAGTGAGGAAGAAAGTCTTATTGAATCTGTATTTGAAGACTATTTGGTTCAAGCTTTGAAAAAAGAAACATAT
TCCTTAAATGACCTTCTATTAATTTCATACTATGCATTTCGATGTCAGGATTATGACTATGATAAAGAGAGAATTGAAAA
ATTTAGACGAAAATTAATTAATCAAGAATTACAAGGTGAAGAGCTGTTTAATGTTGAACTGATAGGTGCTTTATCAGCTA
TAGCTGGGATATATGTAATGCATCATGACTATAAAGAAATGAAGTCTGTTGTTGATAAAATGTATGTTCTTATTGATAAG
ACACTTCAACAAGCTTATAAACCCGCAGTACTTGTTTTTGAAGCGAAATATTATCTATTCTATGAGAACAATAGAGATAA
AGCAACCGAGCTCTATAATACAGCTACCGTACTAGCCGAAGCTTTTGGTGACCAAGTCTTCATCAAAAATCTTAAAATGG
AAATGGAAAATGATTTAGATACAAGTAACGAATCAAAGTGA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (77-295)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	40.339	96.405	0.389
comR	Streptococcus salivarius strain HSISS4	40.69	94.771	0.386
comR	Streptococcus thermophilus LMD-9	40.345	94.771	0.382
comR	Streptococcus thermophilus LMG 18311	40.345	94.771	0.382
comR	Streptococcus salivarius SK126	40.493	92.81	0.376
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	38.832	95.098	0.369