Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   AR327_RS20135 Genome accession   NZ_CP014643
Coordinates   4121224..4122483 (-) Length   419 a.a.
NCBI ID   WP_012293330.1    Uniprot ID   W7RVJ8
Organism   Lysinibacillus sphaericus strain OT4b.25     
Function   unknown (predicted from homology)   
Unclear

Genomic Context

Location: 4116224..4127483
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AR327_RS20115 (AR327_20115) - 4117008..4117772 (-) 765 WP_012293333.1 tyrosine-protein phosphatase -
  AR327_RS20120 (AR327_20120) rny 4117919..4119478 (-) 1560 WP_012293332.1 ribonuclease Y -
  AR327_RS20130 (AR327_20130) recA 4120002..4121063 (-) 1062 WP_031419019.1 recombinase RecA Machinery gene
  AR327_RS20135 (AR327_20135) cinA 4121224..4122483 (-) 1260 WP_012293330.1 competence/damage-inducible protein A Machinery gene
  AR327_RS20140 (AR327_20140) pgsA 4122501..4123079 (-) 579 WP_031419015.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AR327_RS20145 (AR327_20145) - 4123127..4124056 (-) 930 WP_012293328.1 helix-turn-helix domain-containing protein -
  AR327_RS20150 (AR327_20150) - 4124073..4124858 (-) 786 WP_008178931.1 DUF3388 domain-containing protein -
  AR327_RS20155 (AR327_20155) - 4125085..4125342 (-) 258 WP_008178933.1 DUF3243 domain-containing protein -
  AR327_RS20160 (AR327_20160) ymfI 4125387..4126115 (-) 729 WP_012293326.1 elongation factor P 5-aminopentanone reductase -
  AR327_RS20165 (AR327_20165) yfmH 4126115..4127413 (-) 1299 WP_012293325.1 EF-P 5-aminopentanol modification-associated protein YfmH -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45348.60 Da        Isoelectric Point: 4.7670

>NTDB_id=172953 AR327_RS20135 WP_012293330.1 4121224..4122483(-) (cinA) [Lysinibacillus sphaericus strain OT4b.25]
MNAEILAVGSELLLGQITNTNARFISNQLSELGINVFYHTVVGDNAKRLEQAIEVAESRADLIIFSGGLGPTKDDLTKET
IARHLGVSLEFDEVALTYIEQFFAKRGRPMTENNRKQALILAGSEILANHHGMAPGMIFNNNNHTYILLPGPPKELEPMF
QFEAKPKLAAMLNDGGIIASHVMRFYGIGEAELEVQVQDILDAQTNPTVAPLASDGEVTLRVTAKAETEQQAQQLIAAKV
AEIQALVGDYQYGMDDDSLASKTVEMLLDNHLTISAAESLTAGLFQSELAEIPGVGDALIGGVVTYAAEAKVKHLGISQE
LIDTHGVVSGECAAAMASAVRKQFGTNIGIGLTGEAGPTAHDHQPVGTVWIGIAINDEEPLTYLLHLSGMRNTNRLRAVK
FTCHYLMQLLEERGYTKRY

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=172953 AR327_RS20135 WP_012293330.1 4121224..4122483(-) (cinA) [Lysinibacillus sphaericus strain OT4b.25]
ATGAATGCTGAAATTCTAGCGGTGGGCTCAGAGCTATTATTAGGTCAAATTACGAATACAAATGCGAGATTTATCTCGAA
CCAGTTATCCGAGCTAGGCATTAATGTTTTTTACCATACAGTAGTTGGTGATAATGCAAAACGTTTAGAACAAGCTATTG
AAGTGGCAGAATCTCGTGCAGATTTAATTATATTTTCGGGAGGACTAGGACCTACGAAAGATGATTTAACAAAAGAAACG
ATTGCTCGCCATCTCGGTGTTTCTCTTGAGTTTGATGAGGTAGCATTAACTTATATTGAGCAGTTTTTTGCCAAGCGAGG
ACGTCCTATGACGGAGAATAACCGGAAACAGGCTTTAATTCTAGCTGGAAGCGAAATACTAGCGAATCACCATGGAATGG
CGCCTGGTATGATTTTCAACAATAATAATCATACGTATATCTTACTTCCAGGGCCACCAAAAGAGCTTGAGCCTATGTTT
CAATTTGAGGCGAAGCCTAAACTTGCCGCGATGCTTAATGATGGAGGGATTATTGCCTCACATGTGATGCGTTTTTATGG
CATTGGTGAAGCCGAACTTGAAGTTCAGGTACAGGATATTTTAGATGCTCAAACAAATCCAACCGTCGCTCCACTTGCGT
CGGATGGTGAGGTAACATTGCGCGTAACAGCAAAGGCAGAAACAGAACAGCAAGCCCAGCAACTTATTGCTGCCAAAGTG
GCTGAGATACAAGCCCTTGTTGGTGACTATCAGTATGGTATGGATGATGATTCACTTGCTTCAAAGACAGTTGAAATGCT
CTTAGATAATCATCTTACTATTTCTGCTGCGGAAAGTTTAACAGCAGGATTGTTTCAATCGGAGCTTGCAGAAATTCCAG
GGGTAGGGGACGCACTCATTGGAGGTGTCGTGACCTATGCGGCAGAAGCAAAAGTAAAGCATCTTGGTATTTCACAAGAA
TTAATAGATACGCACGGCGTTGTTAGTGGTGAATGTGCTGCTGCAATGGCAAGTGCAGTTCGGAAACAATTTGGTACAAA
CATTGGAATTGGGCTAACAGGGGAAGCAGGGCCTACAGCACATGACCATCAGCCAGTAGGAACGGTTTGGATTGGTATTG
CCATCAATGATGAGGAGCCACTTACATACTTACTTCATTTATCTGGTATGCGAAATACAAATCGACTTCGTGCAGTGAAA
TTTACATGCCATTATTTAATGCAGCTTTTAGAAGAACGCGGTTATACAAAACGATATTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(257-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W7RVJ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

51.942

98.329

0.511
  cinA Streptococcus mitis SK321

45.195

91.885

0.415
  cinA Streptococcus pneumoniae Rx1

44.909

91.408

0.411
  cinA Streptococcus pneumoniae TIGR4

44.909

91.408

0.411
  cinA Streptococcus pneumoniae R6

44.909

91.408

0.411
  cinA Streptococcus pneumoniae D39

44.648

91.408

0.408
  cinA Streptococcus mitis NCTC 12261

44.416

91.885

0.408
  cinA Streptococcus mutans UA159

44.591

90.453

0.403

Multiple sequence alignment