Detailed information NTG0172405

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: AYM92_RS05035
• Genome accession: NZ_CP014542
• Coordinates: 935367..936203 (+)
• Length: 278 a.a.
• NCBI ID: WP_076639652.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain STAB14018
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 930367..941203

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYM92_RS05005 (AYM92_04845)	-	930849..931289 (+)	441	WP_009880949.1	hypothetical protein	-
AYM92_RS05010 (AYM92_04850)	-	931339..932250 (-)	912	WP_076639650.1	diacylglycerol/lipid kinase family protein	-
AYM92_RS05015 (AYM92_04855)	trhA	932367..933017 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
AYM92_RS05020 (AYM92_04860)	-	933014..933454 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
AYM92_RS05025 (AYM92_04865)	ylqF	933673..934521 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
AYM92_RS05030 (AYM92_04870)	-	934511..935302 (+)	792	WP_076639651.1	ribonuclease HII	-
AYM92_RS05035 (AYM92_04875)	dprA	935367..936203 (+)	837	WP_076639652.1	DNA-processing protein DprA	Machinery gene
AYM92_RS05040 (AYM92_04880)	topA	936310..938439 (+)	2130	WP_076639653.1	type I DNA topoisomerase	-
AYM92_RS09990	-	938514..939398 (-)	885	Protein_927	LysR family transcriptional regulator	-
AYM92_RS05055 (AYM92_04890)	-	939411..939977 (+)	567	Protein_928	PTS sugar transporter subunit IIC	-
AYM92_RS05060 (AYM92_04895)	-	939992..940944 (+)	953	Protein_929	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30978.99 Da
• Isoelectric Point: 9.2511

>NTDB_id=172405 AYM92_RS05035 WP_076639652.1 935367..936203(+) (dprA) [Streptococcus pyogenes strain STAB14018]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=172405 AYM92_RS05035 WP_076639652.1 935367..936203(+) (dprA) [Streptococcus pyogenes strain STAB14018]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCACCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363