Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   BKM67_RS00365 Genome accession   NZ_CP017667
Coordinates   62165..63064 (+) Length   299 a.a.
NCBI ID   WP_105184195.1    Uniprot ID   -
Organism   Streptococcus suis strain 1081     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 57165..68064
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM67_RS00345 (BKM67_00340) ruvB 57253..58254 (+) 1002 WP_105183594.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  BKM67_RS00350 (BKM67_00345) - 58322..58945 (+) 624 WP_044676020.1 HAD-IA family hydrolase -
  BKM67_RS00355 (BKM67_00350) - 58857..60412 (-) 1556 Protein_50 IS1182 family transposase -
  BKM67_RS00360 (BKM67_00355) - 60483..61954 (-) 1472 Protein_51 IS1182 family transposase -
  BKM67_RS00365 (BKM67_00360) comR 62165..63064 (+) 900 WP_105184195.1 helix-turn-helix domain-containing protein Regulator
  BKM67_RS00370 (BKM67_00365) - 63281..64501 (+) 1221 WP_105184194.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  BKM67_RS00380 (BKM67_00375) - 64692..66215 (+) 1524 WP_105184193.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35348.22 Da        Isoelectric Point: 4.3358

>NTDB_id=170389 BKM67_RS00365 WP_105184195.1 62165..63064(+) (comR) [Streptococcus suis strain 1081]
MNDKEFGQRVRQLRETASLTREQFCGDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMEKRADMMTEIYDDYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIQRKPQFSAND
LLIIRLYLINLRMEIKQSSDFQHFLELVEKFPSQVELVESGDLFILRDVMLTSIGILGEHEEYGKIPPLFDALDRIMVST
QDFQKKPILNLLKWKYELYVNNDSEEARRFYEEAVMFAKLIGDTHLVEKLESSWREEEK

Nucleotide


Download         Length: 900 bp        

>NTDB_id=170389 BKM67_RS00365 WP_105184195.1 62165..63064(+) (comR) [Streptococcus suis strain 1081]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACTGCTAGTCTGACACGTGAACAGTTTTGCGGTGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGTATGGGGCTCTATGAGCTTATGCCAGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAG
TTTGATGTCCTCCGTACACCGACTTATGAAAATGAGGAATTGATGGAAAAACGTGCAGATATGATGACAGAAATCTATGA
TGACTATTATGATGACTTGCCTGAAGAAGAGAAAATAGCGATTGATGCCATTCAATCTATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAAATCCAAAGAAAACCCCAATTTTCAGCCAACGAT
TTGTTGATAATTCGACTCTATTTAATCAATTTGAGAATGGAAATTAAACAGAGCAGTGATTTTCAGCACTTTTTAGAGTT
GGTTGAAAAGTTTCCGAGCCAAGTAGAATTAGTTGAATCTGGGGATTTGTTTATTTTAAGGGATGTGATGCTGACGTCGA
TAGGGATTCTTGGCGAACATGAAGAATATGGTAAGATACCTCCACTTTTTGATGCTCTAGATAGAATCATGGTTTCAACT
CAAGATTTTCAAAAGAAACCCATTCTCAATCTGCTTAAGTGGAAATATGAGTTGTATGTGAACAATGATAGCGAGGAGGC
TAGACGGTTTTATGAAGAAGCAGTTATGTTCGCAAAATTAATTGGAGACACCCATTTAGTAGAAAAACTAGAATCATCAT
GGAGAGAAGAGGAAAAGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

67.797

98.662

0.669
  comR Streptococcus suis 05ZYH33

67.797

98.662

0.669
  comR Streptococcus suis D9

61.538

100

0.615
  comR Streptococcus mutans UA159

42.14

100

0.421
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.236

96.321

0.378
  comR Streptococcus pyogenes MGAS8232

37.374

99.331

0.371
  comR Streptococcus pyogenes MGAS315

37.5

98.997

0.371