Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   AXE83_RS07000 Genome accession   NZ_CP014264
Coordinates   1484240..1484911 (-) Length   223 a.a.
NCBI ID   WP_000590624.1    Uniprot ID   -
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1479240..1489911
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS06975 (AXE83_06975) - 1479249..1480178 (-) 930 WP_060955910.1 peptidase U32 family protein -
  AXE83_RS06980 (AXE83_06980) - 1480417..1481097 (-) 681 WP_060955911.1 ABC transporter ATP-binding protein -
  AXE83_RS06985 (AXE83_06985) - 1481111..1482166 (-) 1056 WP_060955912.1 ABC transporter permease -
  AXE83_RS06990 (AXE83_06990) - 1482528..1482803 (+) 276 WP_060955913.1 DUF3270 family protein -
  AXE83_RS06995 (AXE83_06995) ciaH 1482913..1484247 (-) 1335 WP_060955914.1 HAMP domain-containing sensor histidine kinase Regulator
  AXE83_RS07000 (AXE83_07000) ciaR 1484240..1484911 (-) 672 WP_000590624.1 response regulator transcription factor Regulator
  AXE83_RS07005 (AXE83_07005) - 1485027..1487573 (-) 2547 WP_060955915.1 M1 family metallopeptidase -
  AXE83_RS07010 (AXE83_07010) - 1487696..1488136 (-) 441 WP_060955916.1 ASCH domain-containing protein -
  AXE83_RS07015 (AXE83_07015) - 1488133..1488981 (-) 849 WP_060955917.1 putative PEP-binding protein -
  AXE83_RS07020 (AXE83_07020) - 1489023..1489751 (-) 729 WP_060955918.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25362.15 Da        Isoelectric Point: 4.3826

>NTDB_id=170007 AXE83_RS07000 WP_000590624.1 1484240..1484911(-) (ciaR) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGISTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLSYGDLTVNLSTNEVRVNDTVVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGSVFAENLQTLRSVGYILKHV

Nucleotide


Download         Length: 672 bp        

>NTDB_id=170007 AXE83_RS07000 WP_000590624.1 1484240..1484911(-) (ciaR) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGATCAAGATTCTATTAGTGGAAGATGACCTAGGCCTATCAAATTCAGTCTTTGATTTTTTGGATGATTTTGCGGATGT
CATGCAGGTTTTTGATGGTGAAGAAGGTCTTTATGAGGCTGAAAGTGGCGTTTATGACTTGATTTTATTGGACTTGATGT
TACCTGAGAAAAATGGGTTTCAAGTTTTAAAAGAATTGCGTGAAAAAGGAATTTCGACTCCTGTTCTGATCATGACAGCC
AAGGAAAGTCTTGATGATAAGGGACATGGATTTGAGCTTGGGGCAGATGATTATCTAACAAAACCATTTTATCTAGAAGA
GCTCAAGATGCGTATCCAAGCACTGCTCAAACGTTCTGGTAAGTTCAATGAAAATACCCTCTCTTATGGTGATTTGACGG
TTAATCTATCTACCAATGAGGTTAGAGTTAATGATACTGTTGTGGAACTATTGGGTAAAGAATTTGATCTCTTGGTTTAT
TTCCTCCAAAATCAAAATGTTATCTTACCAAAAACACAAATTTTTGACCGTTTGTGGGGATTTGACAGTGACACAACCAT
CTCCGTGGTAGAAGTCTATGTATCAAAAGTTCGTAAGAAATTGAAGGGCTCAGTCTTTGCTGAAAACCTCCAAACCTTGC
GTAGTGTTGGGTATATTTTAAAACATGTTTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

94.17

100

0.942
  ciaR Streptococcus pneumoniae D39

94.17

100

0.942
  ciaR Streptococcus pneumoniae R6

94.17

100

0.942
  ciaR Streptococcus pneumoniae TIGR4

94.17

100

0.942
  ciaR Streptococcus mutans UA159

88.688

99.103

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.778

100

0.381
  vicR Streptococcus mutans UA159

35.622

100

0.372

Multiple sequence alignment