Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   AXE83_RS00745 Genome accession   NZ_CP014264
Coordinates   133818..135167 (+) Length   449 a.a.
NCBI ID   WP_060955047.1    Uniprot ID   A0A0X8JWG6
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 128818..140167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS11485 (AXE83_00705) - 129335..129478 (+) 144 WP_060955041.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  AXE83_RS11490 (AXE83_00710) - 129496..129645 (+) 150 WP_060955042.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  AXE83_RS11135 - 129658..129834 (+) 177 WP_190279315.1 hypothetical protein -
  AXE83_RS11140 - 130045..130200 (+) 156 WP_190279316.1 hypothetical protein -
  AXE83_RS11325 (AXE83_00715) - 130239..130451 (+) 213 WP_060955043.1 hypothetical protein -
  AXE83_RS00720 (AXE83_00720) - 130532..130720 (+) 189 WP_060955044.1 hypothetical protein -
  AXE83_RS00730 (AXE83_00730) - 131061..131297 (+) 237 WP_060955045.1 hypothetical protein -
  AXE83_RS11335 (AXE83_00735) - 131290..131481 (+) 192 WP_060956342.1 hypothetical protein -
  AXE83_RS00740 (AXE83_00740) comA 131652..133805 (+) 2154 WP_060955046.1 peptide cleavage/export ABC transporter ComA Regulator
  AXE83_RS00745 (AXE83_00745) comB 133818..135167 (+) 1350 WP_060955047.1 bacteriocin secretion accessory protein Regulator
  AXE83_RS00750 (AXE83_00750) purC 135336..136043 (+) 708 WP_060955048.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  AXE83_RS00755 (AXE83_00755) - 136107..139832 (+) 3726 WP_060955049.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50044.14 Da        Isoelectric Point: 5.9242

>NTDB_id=169975 AXE83_RS00745 WP_060955047.1 133818..135167(+) (comB) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MQSEFLESAEFYNRRYHNFSSYVIFPSFILFLFLIVFSIFAQKEISLTAGATVEPARIIATIQSSSNSKIVANHLAENKF
VKQGDLLVQYQEGAEAVQAENYASQLEMLKDQKVQLEYLKASLQAGSDQFPEADKFGYQHSFLDYLNQAASLRSQVEQQN
ASISSQNAAASGSQTELGNLIGETQSKIKEYQQAKSAIQADRVLESDHPAYAIYQSYQSTKEQGSEAKQQALSQLDAHIT
QLESTLAGYRVQYAGSGAQQAYASGLGSQLESLKSQQLAKVGQELTLLDQKILEVESGKKIQGNLLEKGKITATEDGVLH
LNPEYSRSTIIPEGTILAHLFPQLTRERKAKLTAYISSKEVADLKHGNEVRFTTVTDANKQLVLTSKITNIDTSATQTEK
GNFFKLEAETDLNAEQAEKLRYGLEGRLTMITGRKSFLRYYLDRFLKQE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=169975 AXE83_RS00745 WP_060955047.1 133818..135167(+) (comB) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGCAATCAGAATTTTTAGAAAGTGCTGAGTTTTACAATCGTCGTTACCATAATTTTTCTAGTTATGTGATTTTTCCAAG
TTTTATCTTGTTTTTGTTCCTGATCGTTTTTTCAATCTTTGCACAAAAGGAGATAAGCTTGACAGCTGGAGCTACGGTAG
AACCTGCTCGTATCATTGCCACCATTCAGTCTAGTAGTAATAGTAAGATTGTTGCGAACCATTTGGCTGAAAATAAGTTT
GTCAAGCAAGGGGATCTTCTCGTTCAATACCAAGAGGGAGCAGAAGCAGTTCAGGCTGAGAATTATGCTAGTCAGTTGGA
AATGCTCAAGGATCAGAAGGTTCAACTAGAGTATTTAAAAGCAAGCCTTCAAGCAGGAAGTGATCAATTTCCTGAAGCAG
ATAAATTTGGCTATCAGCATAGTTTTTTAGATTATCTAAATCAAGCTGCTAGTCTGCGAAGTCAGGTTGAGCAGCAAAAT
GCTAGTATATCATCTCAAAATGCAGCAGCCAGTGGTAGTCAGACAGAGTTAGGCAATCTCATCGGTGAAACCCAGTCCAA
AATTAAAGAATATCAGCAAGCCAAGTCTGCTATTCAAGCTGATAGAGTCTTAGAGAGTGATCATCCAGCTTATGCCATTT
ATCAGTCTTATCAGTCAACAAAAGAGCAGGGATCGGAAGCCAAACAGCAGGCCTTATCTCAGCTAGATGCTCACATCACT
CAGTTGGAGTCAACTCTTGCAGGTTATCGAGTACAGTATGCAGGTTCAGGAGCCCAGCAAGCTTATGCATCTGGATTAGG
AAGTCAGTTGGAGTCATTAAAATCTCAGCAACTAGCCAAGGTAGGCCAGGAATTAACGCTCTTGGATCAGAAAATTCTTG
AAGTGGAGTCAGGTAAAAAGATTCAAGGAAATCTTTTAGAGAAGGGGAAAATTACAGCAACAGAAGATGGTGTTCTACAT
TTGAATCCTGAGTATAGTCGATCTACCATCATTCCAGAAGGAACTATCCTCGCTCACCTTTTTCCACAGTTGACTAGAGA
GAGAAAGGCAAAGCTGACAGCTTATATCAGTTCTAAGGAAGTGGCTGATCTCAAGCATGGAAATGAGGTAAGATTTACAA
CGGTAACGGATGCCAATAAGCAGCTAGTGTTGACATCCAAGATTACCAATATCGATACCAGTGCAACTCAGACAGAAAAG
GGCAATTTCTTTAAATTAGAGGCAGAGACGGATTTGAATGCTGAACAAGCAGAAAAACTTCGTTATGGACTTGAAGGTCG
TTTGACTATGATTACAGGTAGGAAGAGTTTTTTACGCTACTATCTGGATCGTTTTTTGAAACAAGAATAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(311-423)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0X8JWG6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

67.706

100

0.677
  comB Streptococcus pneumoniae Rx1

67.706

100

0.677
  comB Streptococcus pneumoniae D39

67.706

100

0.677
  comB Streptococcus pneumoniae R6

67.706

100

0.677
  comB Streptococcus pneumoniae TIGR4

67.483

100

0.675
  comB Streptococcus mitis NCTC 12261

66.592

100

0.666
  comB Streptococcus gordonii str. Challis substr. CH1

53.898

100

0.539

Multiple sequence alignment