Detailed information NTG0166318

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: AVT04_RS03470
• Genome accession: NZ_CP013939
• Coordinates: 659179..660078 (-)
• Length: 299 a.a.
• NCBI ID: WP_011226854.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S9
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 654179..665078

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AVT04_RS03430 (AVT04_03430)	-	654180..654695 (-)	516	WP_011226861.1	AmiS/UreI family transporter	-
AVT04_RS11030	-	655100..655471 (+)	372	WP_231108754.1	hypothetical protein	-
AVT04_RS11035	-	655695..655997 (+)	303	WP_011226859.1	hypothetical protein	-
AVT04_RS11040	-	656237..656521 (+)	285	WP_231108755.1	hypothetical protein	-
AVT04_RS03440 (AVT04_03440)	-	656489..656800 (-)	312	WP_011226857.1	DUF805 domain-containing protein	-
AVT04_RS03445 (AVT04_03445)	-	656908..657476 (-)	569	Protein_664	ATP-binding cassette domain-containing protein	-
AVT04_RS09805 (AVT04_03460)	-	657762..659003 (-)	1242	Protein_665	ABC transporter transmembrane domain-containing protein	-
AVT04_RS03470 (AVT04_03470)	comR	659179..660078 (-)	900	WP_011226854.1	helix-turn-helix domain-containing protein	Regulator
AVT04_RS03475 (AVT04_03475)	-	660273..660923 (-)	651	WP_011226853.1	phosphatase PAP2 family protein	-
AVT04_RS03480 (AVT04_03480)	-	660926..661483 (-)	558	WP_002949523.1	ECF transporter S component	-
AVT04_RS03485 (AVT04_03485)	-	661795..662334 (-)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
AVT04_RS03490 (AVT04_03490)	trkA	662593..663942 (+)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35317.79 Da
• Isoelectric Point: 5.1073

>NTDB_id=166318 AVT04_RS03470 WP_011226854.1 659179..660078(-) (comR) [Streptococcus thermophilus strain S9]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLIIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=166318 AVT04_RS03470 WP_011226854.1 659179..660078(-) (comR) [Streptococcus thermophilus strain S9]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAATCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421