Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   AV904_RS04380 Genome accession   NZ_CP013911
Coordinates   903408..904274 (+) Length   288 a.a.
NCBI ID   WP_011275951.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain S167     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 869515..917124 903408..904274 within 0


Gene organization within MGE regions


Location: 869515..917124
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AV904_RS04235 (AV904_04245) rsgA 870854..871729 (+) 876 WP_011275979.1 ribosome small subunit-dependent GTPase A -
  AV904_RS04240 (AV904_04250) rpe 871729..872373 (+) 645 WP_011275978.1 ribulose-phosphate 3-epimerase -
  AV904_RS04245 (AV904_04255) - 872381..873022 (+) 642 WP_011275977.1 thiamine diphosphokinase -
  AV904_RS04250 (AV904_04260) rpmB 873083..873271 (-) 189 WP_011275976.1 50S ribosomal protein L28 -
  AV904_RS04255 (AV904_04265) - 873554..873922 (+) 369 WP_011275975.1 Asp23/Gls24 family envelope stress response protein -
  AV904_RS04260 (AV904_04270) fakA 873943..875601 (+) 1659 WP_011275974.1 fatty acid kinase catalytic subunit FakA -
  AV904_RS04265 (AV904_04275) - 875787..876587 (+) 801 WP_011275973.1 thermonuclease family protein -
  AV904_RS04270 (AV904_04280) recG 876742..878793 (+) 2052 WP_016930693.1 ATP-dependent DNA helicase RecG -
  AV904_RS04275 (AV904_04285) fapR 878929..879489 (+) 561 WP_011275971.1 transcription factor FapR -
  AV904_RS04280 (AV904_04290) plsX 879491..880477 (+) 987 WP_011275970.1 phosphate acyltransferase PlsX -
  AV904_RS04285 (AV904_04295) fabD 880470..881399 (+) 930 WP_062931953.1 ACP S-malonyltransferase -
  AV904_RS04290 (AV904_04300) fabG 881389..882126 (+) 738 WP_011275968.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  AV904_RS04295 (AV904_04305) - 882239..882472 (+) 234 WP_001830184.1 acyl carrier protein -
  AV904_RS04300 (AV904_04310) rnc 882543..883295 (+) 753 WP_210423027.1 ribonuclease III -
  AV904_RS04305 (AV904_04315) smc 883380..886949 (+) 3570 WP_053017387.1 chromosome segregation protein SMC -
  AV904_RS04310 (AV904_04320) ftsY 886946..888169 (+) 1224 WP_053017389.1 signal recognition particle-docking protein FtsY -
  AV904_RS04315 (AV904_04325) - 888156..888488 (+) 333 WP_037537868.1 putative DNA-binding protein -
  AV904_RS04320 (AV904_04330) ffh 888514..889884 (+) 1371 WP_053038594.1 signal recognition particle protein -
  AV904_RS04325 (AV904_04335) rpsP 890130..890405 (+) 276 WP_011275962.1 30S ribosomal protein S16 -
  AV904_RS04330 (AV904_04340) rimM 890524..891027 (+) 504 WP_037557996.1 ribosome maturation factor RimM -
  AV904_RS04335 (AV904_04345) trmD 891027..891764 (+) 738 WP_037557997.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  AV904_RS04340 (AV904_04350) rplS 891869..892219 (+) 351 WP_037537864.1 50S ribosomal protein L19 -
  AV904_RS04345 (AV904_04355) - 892377..894986 (-) 2610 WP_037557998.1 YfhO family protein -
  AV904_RS04350 (AV904_04360) - 894988..897582 (-) 2595 WP_053038595.1 YfhO family protein -
  AV904_RS04355 (AV904_04365) ylqF 897820..898704 (+) 885 WP_011275956.1 ribosome biogenesis GTPase YlqF -
  AV904_RS04360 (AV904_04370) - 898688..899455 (+) 768 WP_053038596.1 ribonuclease HII -
  AV904_RS04365 (AV904_04375) sucC 899567..900733 (+) 1167 WP_011275954.1 ADP-forming succinate--CoA ligase subunit beta -
  AV904_RS04370 (AV904_04380) sucD 900755..901660 (+) 906 WP_011275953.1 succinate--CoA ligase subunit alpha -
  AV904_RS04375 (AV904_04385) - 901960..903189 (+) 1230 WP_011275952.1 aminoacyltransferase -
  AV904_RS04380 (AV904_04390) dprA 903408..904274 (+) 867 WP_011275951.1 DNA-processing protein DprA Machinery gene
  AV904_RS04385 (AV904_04395) topA 904453..906522 (+) 2070 WP_011275950.1 type I DNA topoisomerase -
  AV904_RS04390 (AV904_04400) trmFO 906546..907853 (+) 1308 WP_011275949.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  AV904_RS04395 (AV904_04405) xerC 908028..908891 (+) 864 WP_222127965.1 tyrosine recombinase XerC -
  AV904_RS04400 (AV904_04410) hslV 908892..909437 (+) 546 WP_011275947.1 ATP-dependent protease subunit HslV -
  AV904_RS04405 (AV904_04415) hslU 909496..910899 (+) 1404 WP_011275946.1 ATP-dependent protease ATPase subunit HslU -
  AV904_RS04410 (AV904_04420) codY 910921..911694 (+) 774 WP_011275945.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  AV904_RS04415 (AV904_04425) rpsB 911961..912749 (+) 789 WP_011275944.1 30S ribosomal protein S2 -
  AV904_RS04420 (AV904_04430) tsf 912907..913785 (+) 879 WP_011275943.1 translation elongation factor Ts -
  AV904_RS04425 (AV904_04435) pyrH 913922..914644 (+) 723 WP_011275942.1 UMP kinase -
  AV904_RS04430 (AV904_04440) frr 914662..915216 (+) 555 WP_062931954.1 ribosome recycling factor -
  AV904_RS04435 (AV904_04445) - 915442..916212 (+) 771 WP_011275940.1 isoprenyl transferase -
  AV904_RS04440 (AV904_04450) - 916216..916998 (+) 783 WP_037537321.1 phosphatidate cytidylyltransferase -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 33058.12 Da        Isoelectric Point: 9.4081

>NTDB_id=165994 AV904_RS04380 WP_011275951.1 903408..904274(+) (dprA) [Staphylococcus haemolyticus strain S167]
MTNNNILLLKLIWLGYTTQHIHHLLKLNPEFFKFSYTDQIDSIKNWDKLFHKGDFIDRYNHLNDKEILSFLNQHKISFVT
PFNANYPRLLKEIYDYPFVLFYQGDPQLLTSPNTLGVVGSRNATEYSAKAMQYLFPKFKQIPLTIISGLAKGADSIAHHF
AIEYQLPTIAVLGFGHMMHYPRETQKLRNIIEVKGLVISEYPPFTSVRRYHFPQRNRLISGLSQGVLITEASVRSGSQIT
IDCALDQNRNIYVLPGSIFNPLTKGNLKRAQEGAMIVTSADDILCDYK

Nucleotide


Download         Length: 867 bp        

>NTDB_id=165994 AV904_RS04380 WP_011275951.1 903408..904274(+) (dprA) [Staphylococcus haemolyticus strain S167]
ATGACTAACAACAACATATTACTTTTGAAATTAATTTGGTTAGGTTATACGACCCAACATATTCATCATTTATTAAAATT
AAATCCTGAATTTTTTAAATTCTCTTATACTGATCAAATAGATTCAATAAAAAATTGGGACAAGTTATTTCATAAAGGTG
ATTTTATTGATCGATATAATCATTTAAATGATAAAGAAATTTTGTCATTTTTGAATCAACACAAGATAAGTTTTGTAACA
CCGTTTAACGCTAATTATCCTCGACTATTAAAAGAAATTTATGATTATCCGTTTGTCCTATTTTACCAAGGTGACCCCCA
ATTATTAACATCCCCCAATACATTAGGTGTGGTGGGCTCAAGAAATGCAACAGAGTACTCAGCTAAAGCCATGCAATACT
TATTTCCTAAATTTAAACAAATTCCACTAACCATTATTTCCGGTTTGGCAAAAGGTGCTGATAGCATTGCACATCATTTT
GCTATAGAGTATCAATTACCTACTATAGCTGTTTTAGGTTTTGGTCATATGATGCATTACCCTAGAGAAACGCAAAAATT
ACGCAACATAATTGAAGTAAAAGGTTTAGTTATTAGTGAATATCCGCCATTCACTAGTGTTAGGCGATATCACTTTCCGC
AACGCAATCGTTTGATAAGCGGTCTTTCACAAGGGGTTTTAATAACTGAAGCAAGTGTTAGAAGCGGTAGTCAAATTACA
ATTGATTGCGCATTAGACCAAAATAGAAATATATATGTATTACCAGGTTCAATATTTAATCCACTAACTAAAGGTAATTT
GAAACGAGCTCAAGAAGGTGCGATGATTGTAACCTCAGCTGATGATATTCTATGTGATTATAAATAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

49.825

98.958

0.493
  dprA Staphylococcus aureus N315

49.825

98.958

0.493
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae D39

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae R6

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

36.395

100

0.372
  dprA Streptococcus mutans UA159

37.544

98.958

0.372
  dprA/cilB/dalA Streptococcus mitis SK321

35.374

100

0.361
  dprA Legionella pneumophila strain ERS1305867

42.105

85.764

0.361

Multiple sequence alignment