Detailed information NTG0165122

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MGAS27061_RS04410
• Genome accession: NZ_CP013840
• Coordinates: 887121..887957 (+)
• Length: 278 a.a.
• NCBI ID: WP_031488274.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS27061
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 882121..892957

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS27061_RS04380 (MGAS27061_0895)	-	882606..883043 (+)	438	WP_031488279.1	hypothetical protein	-
MGAS27061_RS04385 (MGAS27061_0896)	-	883093..884004 (-)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
MGAS27061_RS04390 (MGAS27061_0897)	trhA	884121..884771 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
MGAS27061_RS04395 (MGAS27061_0898)	-	884768..885208 (-)	441	WP_031488277.1	DUF1836 domain-containing protein	-
MGAS27061_RS04400 (MGAS27061_0899)	ylqF	885427..886275 (+)	849	WP_031488276.1	ribosome biogenesis GTPase YlqF	-
MGAS27061_RS04405 (MGAS27061_0900)	-	886265..887056 (+)	792	WP_031488275.1	ribonuclease HII	-
MGAS27061_RS04410 (MGAS27061_0901)	dprA	887121..887957 (+)	837	WP_031488274.1	DNA-processing protein DprA	Machinery gene
MGAS27061_RS04415 (MGAS27061_0902)	topA	888064..890193 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
MGAS27061_RS08905	-	890268..891125 (-)	858	Protein_850	LysR family transcriptional regulator	-
MGAS27061_RS04425 (MGAS27061_0905)	-	891165..891710 (+)	546	Protein_851	PTS sugar transporter subunit IIC	-
MGAS27061_RS04430 (MGAS27061_0906)	-	891725..892717 (+)	993	WP_031488271.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30960.96 Da
• Isoelectric Point: 9.2511

>NTDB_id=165122 MGAS27061_RS04410 WP_031488274.1 887121..887957(+) (dprA) [Streptococcus pyogenes strain MGAS27061]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=165122 MGAS27061_RS04410 WP_031488274.1 887121..887957(+) (dprA) [Streptococcus pyogenes strain MGAS27061]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363