Detailed information NTG0165070

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MGAS23530_RS04220
• Genome accession: NZ_CP013839
• Coordinates: 853593..854429 (+)
• Length: 278 a.a.
• NCBI ID: WP_031488274.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS23530
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 848593..859429

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS23530_RS04190 (MGAS23530_0860)	-	849078..849515 (+)	438	WP_031488279.1	hypothetical protein	-
MGAS23530_RS04195 (MGAS23530_0861)	-	849565..850476 (-)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
MGAS23530_RS04200 (MGAS23530_0862)	trhA	850593..851243 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
MGAS23530_RS04205 (MGAS23530_0863)	-	851240..851680 (-)	441	WP_031488277.1	DUF1836 domain-containing protein	-
MGAS23530_RS04210 (MGAS23530_0864)	ylqF	851899..852747 (+)	849	WP_031488276.1	ribosome biogenesis GTPase YlqF	-
MGAS23530_RS04215 (MGAS23530_0865)	-	852737..853528 (+)	792	WP_031488275.1	ribonuclease HII	-
MGAS23530_RS04220 (MGAS23530_0866)	dprA	853593..854429 (+)	837	WP_031488274.1	DNA-processing protein DprA	Machinery gene
MGAS23530_RS04225 (MGAS23530_0867)	topA	854536..856665 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
MGAS23530_RS08700	-	856740..857597 (-)	858	Protein_811	LysR family transcriptional regulator	-
MGAS23530_RS04235 (MGAS23530_0870)	-	857637..858182 (+)	546	Protein_812	PTS sugar transporter subunit IIC	-
MGAS23530_RS04240 (MGAS23530_0871)	-	858197..859189 (+)	993	WP_031488271.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30960.96 Da
• Isoelectric Point: 9.2511

>NTDB_id=165070 MGAS23530_RS04220 WP_031488274.1 853593..854429(+) (dprA) [Streptococcus pyogenes strain MGAS23530]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=165070 MGAS23530_RS04220 WP_031488274.1 853593..854429(+) (dprA) [Streptococcus pyogenes strain MGAS23530]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363