Detailed information NTG0165018

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MGAS11027_RS04765
• Genome accession: NZ_CP013838
• Coordinates: 942759..943595 (+)
• Length: 278 a.a.
• NCBI ID: WP_031488274.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS11027
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 937759..948595

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS11027_RS04735 (MGAS11027_0962)	-	938244..938681 (+)	438	WP_031488279.1	hypothetical protein	-
MGAS11027_RS04740 (MGAS11027_0963)	-	938731..939642 (-)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
MGAS11027_RS04745 (MGAS11027_0964)	trhA	939759..940409 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
MGAS11027_RS04750 (MGAS11027_0965)	-	940406..940846 (-)	441	WP_031488277.1	DUF1836 domain-containing protein	-
MGAS11027_RS04755 (MGAS11027_0966)	ylqF	941065..941913 (+)	849	WP_031488276.1	ribosome biogenesis GTPase YlqF	-
MGAS11027_RS04760 (MGAS11027_0967)	-	941903..942694 (+)	792	WP_031488275.1	ribonuclease HII	-
MGAS11027_RS04765 (MGAS11027_0968)	dprA	942759..943595 (+)	837	WP_031488274.1	DNA-processing protein DprA	Machinery gene
MGAS11027_RS04770 (MGAS11027_0969)	topA	943702..945831 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
MGAS11027_RS09240	-	945906..946763 (-)	858	Protein_920	LysR family transcriptional regulator	-
MGAS11027_RS04780 (MGAS11027_0972)	-	946803..947348 (+)	546	Protein_921	PTS sugar transporter subunit IIC	-
MGAS11027_RS04785 (MGAS11027_0973)	-	947363..948355 (+)	993	WP_031488271.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30960.96 Da
• Isoelectric Point: 9.2511

>NTDB_id=165018 MGAS11027_RS04765 WP_031488274.1 942759..943595(+) (dprA) [Streptococcus pyogenes strain MGAS11027]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=165018 MGAS11027_RS04765 WP_031488274.1 942759..943595(+) (dprA) [Streptococcus pyogenes strain MGAS11027]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363