Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   AU077_RS07550 Genome accession   NZ_CP013688
Coordinates   1510639..1511301 (-) Length   220 a.a.
NCBI ID   WP_014294078.1    Uniprot ID   A0A380K6H1
Organism   Streptococcus gallolyticus strain ICDDRB-NRC-S1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1505639..1516301
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AU077_RS07545 (AU077_07545) hpf 1510015..1510563 (-) 549 WP_014294079.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  AU077_RS07550 (AU077_07550) comFC/cflB 1510639..1511301 (-) 663 WP_014294078.1 ComF family protein Machinery gene
  AU077_RS07555 (AU077_07555) comFA/cflA 1511298..1512599 (-) 1302 WP_014294077.1 DEAD/DEAH box helicase Machinery gene
  AU077_RS07560 (AU077_07560) - 1512656..1513282 (+) 627 WP_058621868.1 YigZ family protein -
  AU077_RS07565 (AU077_07565) cysK 1513386..1514315 (+) 930 WP_014294075.1 cysteine synthase A -
  AU077_RS07570 (AU077_07570) - 1514435..1514791 (-) 357 WP_014294074.1 S1 RNA-binding domain-containing protein -
  AU077_RS07575 (AU077_07575) - 1514791..1516191 (-) 1401 WP_014294073.1 Cof-type HAD-IIB family hydrolase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25869.06 Da        Isoelectric Point: 9.2880

>NTDB_id=164058 AU077_RS07550 WP_014294078.1 1510639..1511301(-) (comFC/cflB) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MICLLCEQEFSKKEQFLNLILMKKDDNGVCLECQKTFERIGDIHCPNCYRNGFAQQCLDCQSWEKKHHHVFHEALFTYNS
SMKDYFSKYKFQGDILLSHVFSKEIKQALKKYKNYTVVPVPISPKRLKERQFNQVTALLQAAKISYEDLLIKIEIRKQSD
KTRKERLETLNPFSFKNISKVPENILIIDDIYTTGATLKGIYQLFYENGAKNVKSFTIVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=164058 AU077_RS07550 WP_014294078.1 1510639..1511301(-) (comFC/cflB) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGATTTGCCTGCTCTGCGAACAAGAATTTTCCAAAAAAGAACAATTTTTAAACCTTATCTTAATGAAAAAAGATGACAA
CGGTGTGTGTCTGGAGTGTCAAAAAACATTTGAAAGAATAGGAGACATTCATTGCCCAAACTGTTACCGCAACGGCTTTG
CTCAGCAATGCTTAGATTGTCAATCATGGGAAAAAAAGCATCACCATGTGTTTCATGAAGCACTTTTTACTTACAACTCT
TCAATGAAAGACTATTTTTCAAAATATAAATTTCAAGGAGATATTCTTTTAAGTCACGTTTTTTCAAAGGAAATCAAACA
AGCATTAAAAAAATATAAAAACTACACCGTTGTTCCAGTTCCCATAAGTCCAAAACGGCTAAAAGAAAGACAATTTAACC
AAGTAACAGCACTTTTACAAGCAGCTAAAATCTCCTATGAAGACTTACTAATCAAGATAGAAATCAGAAAACAGTCCGAT
AAAACACGAAAGGAGCGCCTAGAAACTCTCAATCCTTTTTCTTTTAAAAATATTTCAAAAGTGCCAGAAAATATTTTGAT
TATTGATGATATTTACACAACTGGCGCTACTTTAAAGGGAATATACCAGCTTTTCTATGAAAATGGCGCAAAAAATGTAA
AAAGTTTTACGATTGTGCGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380K6H1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis NCTC 12261

50

100

0.5
  comFC/cflB Streptococcus pneumoniae TIGR4

49.545

100

0.495
  comFC/cflB Streptococcus pneumoniae Rx1

49.545

100

0.495
  comFC/cflB Streptococcus pneumoniae D39

49.545

100

0.495
  comFC/cflB Streptococcus pneumoniae R6

49.545

100

0.495
  comFC/cflB Streptococcus mitis SK321

49.091

100

0.491
  comFC Bacillus subtilis subsp. subtilis str. 168

34.934

100

0.364

Multiple sequence alignment