Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   AU077_RS07555 Genome accession   NZ_CP013688
Coordinates   1511298..1512599 (-) Length   433 a.a.
NCBI ID   WP_014294077.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain ICDDRB-NRC-S1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1506298..1517599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AU077_RS07545 (AU077_07545) hpf 1510015..1510563 (-) 549 WP_014294079.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  AU077_RS07550 (AU077_07550) comFC/cflB 1510639..1511301 (-) 663 WP_014294078.1 ComF family protein Machinery gene
  AU077_RS07555 (AU077_07555) comFA/cflA 1511298..1512599 (-) 1302 WP_014294077.1 DEAD/DEAH box helicase Machinery gene
  AU077_RS07560 (AU077_07560) - 1512656..1513282 (+) 627 WP_058621868.1 YigZ family protein -
  AU077_RS07565 (AU077_07565) cysK 1513386..1514315 (+) 930 WP_014294075.1 cysteine synthase A -
  AU077_RS07570 (AU077_07570) - 1514435..1514791 (-) 357 WP_014294074.1 S1 RNA-binding domain-containing protein -
  AU077_RS07575 (AU077_07575) - 1514791..1516191 (-) 1401 WP_014294073.1 Cof-type HAD-IIB family hydrolase -
  AU077_RS07580 (AU077_07580) - 1516310..1516954 (-) 645 WP_009853571.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49166.35 Da        Isoelectric Point: 9.9437

>NTDB_id=164059 AU077_RS07555 WP_014294077.1 1511298..1512599(-) (comFA/cflA) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MDKLDNYYGRLFTQAQLSDALKKQTKQLPAMTKLNHHYVCNRCGSQVSLQNKLQTNVFYCRICLVFGRNTSNGHLYYFPQ
KCFSKKNSLIWKGKLTPYQDDVSKGMLEGIDAKKDLLIHAVTGAGKTEMIYQSVSKIIDDGGCVCLASPRIDVCLELYKR
LSRDFSCPITLLHGDSESYKRAPLIIATTHQLLKFYQAFDLLIIDEVDAFPFVDNAVLYHAVDKATKPNGTKIFLTATST
DELDKKVKTGTLTKLHLARRFHANPLVVPQKIWLSGILSNMQKKKIPQKLINLLKKQRQTRYPLLIFFPNIEQGEAFTQI
LQTYFPEEQIAFVSSKTENRLEIVEKFRKQELSILVTTTILERGVTFPCVDVFVVLANHRLYTKSALVQISGRVGRAAER
PTGELLFLHDGSTKEMRKAITEIKAMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=164059 AU077_RS07555 WP_014294077.1 1511298..1512599(-) (comFA/cflA) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGGATAAACTGGATAATTATTATGGAAGACTATTTACACAAGCTCAACTTTCGGATGCCTTAAAAAAACAGACTAAACA
GTTACCAGCAATGACAAAATTAAATCATCATTATGTTTGCAATCGTTGTGGTAGTCAAGTATCTTTACAAAACAAACTTC
AAACAAACGTTTTTTATTGTCGAATTTGCCTTGTTTTTGGAAGAAATACGAGTAATGGACATCTCTATTATTTTCCACAA
AAATGTTTTTCTAAAAAAAATTCTCTTATTTGGAAAGGAAAATTGACTCCTTACCAAGATGACGTTTCAAAAGGGATGTT
AGAAGGTATTGATGCTAAGAAAGATCTACTTATTCATGCTGTTACAGGTGCTGGAAAAACAGAAATGATTTACCAATCTG
TATCCAAAATAATTGATGACGGTGGTTGTGTTTGCCTAGCAAGTCCGCGAATTGATGTTTGTCTGGAACTTTATAAACGC
TTGTCACGTGATTTTTCGTGTCCGATTACATTGCTTCATGGAGATTCTGAGTCCTACAAACGTGCCCCTTTAATCATTGC
CACAACACATCAACTTTTAAAATTTTACCAAGCTTTTGATTTGTTAATTATTGATGAAGTTGATGCCTTTCCATTTGTGG
ATAATGCCGTGCTTTACCATGCTGTTGATAAAGCTACCAAACCTAATGGAACCAAGATTTTTTTAACAGCGACATCAACA
GATGAATTAGATAAAAAAGTAAAAACAGGAACTCTGACCAAATTGCACCTTGCTCGACGCTTTCATGCCAATCCATTAGT
TGTGCCACAAAAAATCTGGTTGTCTGGCATTTTATCCAATATGCAAAAGAAGAAAATTCCCCAGAAATTAATAAATCTTC
TGAAAAAACAACGTCAAACCCGCTATCCTTTGCTAATCTTCTTCCCAAACATCGAACAAGGAGAAGCCTTTACTCAAATT
TTACAAACTTACTTTCCAGAAGAACAAATCGCTTTTGTGTCTAGTAAAACAGAAAATCGCTTAGAAATTGTAGAAAAATT
TAGGAAACAAGAACTTTCTATTTTGGTTACAACAACCATTTTAGAACGTGGTGTCACTTTCCCATGCGTAGATGTTTTTG
TAGTGCTTGCCAATCATAGATTATATACCAAAAGCGCGCTAGTTCAGATTTCAGGGCGAGTTGGGAGAGCAGCAGAGCGT
CCAACAGGAGAACTGTTATTCTTGCATGACGGTAGCACTAAAGAAATGAGAAAAGCTATTACTGAAATTAAAGCGATGAA
TAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(287-397)

DEAD/DEAH box helicase (DEAD)

(96-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

59.719

98.614

0.589
  comFA/cflA Streptococcus pneumoniae Rx1

59.719

98.614

0.589
  comFA/cflA Streptococcus pneumoniae D39

59.719

98.614

0.589
  comFA/cflA Streptococcus pneumoniae R6

59.719

98.614

0.589
  comFA/cflA Streptococcus mitis NCTC 12261

59.485

98.614

0.587
  comFA/cflA Streptococcus mitis SK321

58.782

98.614

0.58
  comFA Lactococcus lactis subsp. cremoris KW2

50.238

96.998

0.487
  comFA Latilactobacillus sakei subsp. sakei 23K

38.283

99.538

0.381

Multiple sequence alignment