Detailed information NTG0164050

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: AU077_RS04670
• Genome accession: NZ_CP013688
• Coordinates: 931243..932085 (+)
• Length: 280 a.a.
• NCBI ID: WP_039670791.1
• Uniprot ID: A0A380K8L7
• Organism: Streptococcus gallolyticus strain ICDDRB-NRC-S1
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 926243..937085

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AU077_RS11065	-	927492..927707 (-)	216	WP_158526996.1	hypothetical protein	-
AU077_RS04645 (AU077_04645)	-	927831..928148 (+)	318	WP_039670796.1	hypothetical protein	-
AU077_RS04650 (AU077_04650)	-	928342..928752 (-)	411	WP_039670795.1	DUF4231 domain-containing protein	-
AU077_RS04655 (AU077_04655)	ylqF	928996..929850 (+)	855	WP_039670794.1	ribosome biogenesis GTPase YlqF	-
AU077_RS04660 (AU077_04660)	-	929837..930616 (+)	780	WP_039670793.1	ribonuclease HII	-
AU077_RS04665 (AU077_04665)	-	930618..931169 (+)	552	WP_039670792.1	sugar O-acetyltransferase	-
AU077_RS04670 (AU077_04670)	dprA	931243..932085 (+)	843	WP_039670791.1	DNA-processing protein DprA	Machinery gene
AU077_RS04675 (AU077_04675)	topA	932180..934321 (+)	2142	WP_014294544.1	type I DNA topoisomerase	-
AU077_RS04680 (AU077_04680)	-	934439..935106 (+)	668	Protein_954	SatD family protein	-
AU077_RS04685 (AU077_04685)	-	935106..935826 (+)	721	Protein_955	DUF3307 domain-containing protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31060.12 Da
• Isoelectric Point: 8.6600

>NTDB_id=164050 AU077_RS04670 WP_039670791.1 931243..932085(+) (dprA) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MNNFELFKLKKAGLTNLNILAILDYQEKQEKSLSLRNMAVVSKCKNPILFMEKYKALDTKELHKEFNRFPNISILDGEYP
LELKYCYNPPVLLFYQGNLELLNRSKMAVVGARTASTTGTKSVQKIIKELGNHFVIVSGLARGIDTSAHLSALKNGGASI
AVIGCGLDVYYPKENKQLQEYMAKNHLVLSEYVAGEAPLKFHFPERNRIIAGLSQGVIVVEAKLRSGSLITCERALEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCVISGLDILSEYQI

Nucleotide

• Length: 843 bp

>NTDB_id=164050 AU077_RS04670 WP_039670791.1 931243..932085(+) (dprA) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGAATAATTTTGAACTGTTTAAATTAAAAAAAGCAGGATTAACAAATCTTAATATTTTAGCTATTTTGGATTATCAAGA
AAAGCAAGAGAAATCACTATCTTTGCGTAATATGGCAGTCGTCTCAAAATGTAAAAATCCTATCCTTTTTATGGAAAAAT
ACAAAGCACTGGACACCAAAGAATTGCACAAAGAATTTAATCGTTTTCCTAATATTTCCATACTAGATGGCGAATACCCA
TTAGAGCTCAAATATTGTTATAATCCACCTGTTTTGCTGTTTTATCAAGGAAATTTAGAGTTACTCAATCGCTCCAAAAT
GGCGGTGGTAGGAGCGCGAACAGCCTCAACAACAGGAACTAAATCTGTACAGAAAATCATCAAAGAACTCGGAAATCATT
TTGTTATTGTTAGCGGCCTGGCACGTGGCATTGATACCAGTGCGCATTTATCAGCTCTAAAAAACGGTGGTGCATCGATT
GCCGTTATCGGTTGCGGACTGGACGTTTATTATCCCAAAGAAAACAAGCAGTTGCAGGAGTACATGGCTAAAAATCACCT
CGTATTAAGTGAGTACGTAGCAGGAGAAGCACCGCTGAAATTCCATTTTCCAGAGCGAAATCGTATTATTGCAGGTTTAT
CACAAGGCGTTATCGTAGTAGAAGCTAAGCTGCGCTCAGGCAGTTTGATTACGTGCGAAAGAGCATTGGAAGAAGGACGA
GACGTTTTTGCCATTCCAGGAAATATTTTAGATGGAAAATCTGATGGCTGTCATCATTTGATAAAAGAAGGCGCAAAATG
CGTCATATCAGGCTTAGATATCCTTTCGGAATATCAAATATAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

3D structure

• AlphaFold DB: A0A380K8L7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	73.741	99.286	0.732
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.214	100	0.632
dprA/cilB/dalA	Streptococcus mitis SK321	63.214	100	0.632
dprA	Lactococcus lactis subsp. cremoris KW2	60.791	99.286	0.604
dprA	Haemophilus influenzae Rd KW20	38.636	94.286	0.364