Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ATM98_RS06755 Genome accession   NZ_CP013651
Coordinates   1416100..1418253 (-) Length   717 a.a.
NCBI ID   WP_061564519.1    Uniprot ID   -
Organism   Streptococcus sp. A12     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1411100..1423253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ATM98_RS06745 (ATM98_06745) - 1413980..1414516 (+) 537 WP_006595361.1 TetR/AcrR family transcriptional regulator -
  ATM98_RS06750 (ATM98_06750) comB 1414711..1416072 (-) 1362 WP_061564518.1 bacteriocin secretion accessory protein Regulator
  ATM98_RS06755 (ATM98_06755) comA 1416100..1418253 (-) 2154 WP_061564519.1 peptide cleavage/export ABC transporter ComA Regulator
  ATM98_RS06760 (ATM98_06760) rpsD 1418537..1419148 (-) 612 WP_061564520.1 30S ribosomal protein S4 -
  ATM98_RS06765 (ATM98_06765) - 1419740..1420012 (-) 273 WP_048715069.1 Veg family protein -
  ATM98_RS06770 (ATM98_06770) dnaB 1420016..1421371 (-) 1356 WP_061564521.1 replicative DNA helicase -
  ATM98_RS06775 (ATM98_06775) rplI 1421396..1421848 (-) 453 WP_048690977.1 50S ribosomal protein L9 -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80887.49 Da        Isoelectric Point: 8.9201

>NTDB_id=163414 ATM98_RS06755 WP_061564519.1 1416100..1418253(-) (comA) [Streptococcus sp. A12]
MGFKKKHYRQQVDMRDCGVAALAMVFGYYGSYYSLASLREKAKTTADGTTALGLVKVAEELGFETRAFRADRTLFDLEGV
TYPLIVHVIKDGRLPHYYVVYKKDKKRLYIADPDPKVKMTKLTIEEFEKEWTGIVIALAPTPAYQPSKEKKNGLLDFVPL
LFKQRQLVLHIVLATLLVTLINIVGSYYLQSIIDTYVPDQMKQTLSVISLGLIVVYILQQVLTYAQDYLLLVLGQRLSID
VILSYIKHVFQLPMSFFATRRTGEVVSRFTDANRIIDALASTLLSIFLDLSIVLILSVVLFSQNAHLFFLTILLLPIYAV
IIFAFMKPFERLNNETMEANSVLSSSIIEDINGIETIKSLTSERSRYQKIDSEFVDYLKKSFAMSKAESLQKGLKHLAQL
ILNVLVLWLGAHLVMKQELSLGQLITYNTLLVYFTGPLENLINLQTKLQAARVANTRLNEVYLIDSEFAEKKPLQKREAL
DGDLVFEGVDYKYGFGANVLTDISLTIKKGSKVSFVGISGSGKTTLAKMMVNFYQPNKGTIRLGGTDIQQVDKTLLRQQI
NYLPQQPYVFNGTILENLLLGAREGTSQEDILRAVEIAGIREDIERMPLNYQTELTTDGMGISGGQRQRIALARALLTDA
PILILDEATSSLDILTEKKIVDRLMALDKTIIFIAHRLTIAERSEKVFLMDQGRLKEEGSHEELLKKNGYYSHLVTC

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=163414 ATM98_RS06755 WP_061564519.1 1416100..1418253(-) (comA) [Streptococcus sp. A12]
ATGGGATTTAAGAAAAAACATTATCGCCAACAAGTTGATATGAGAGACTGCGGTGTTGCAGCTTTGGCCATGGTCTTTGG
CTACTATGGCTCATACTATTCTTTAGCTAGCCTGCGGGAGAAGGCAAAAACGACTGCAGATGGAACGACCGCCTTAGGTC
TGGTCAAGGTGGCTGAGGAGTTGGGATTTGAGACACGCGCCTTCCGAGCAGATCGTACACTTTTTGACTTGGAAGGAGTG
ACCTATCCATTGATCGTCCACGTGATCAAGGATGGGCGTCTCCCTCATTATTACGTAGTCTATAAGAAAGATAAAAAGCG
TCTTTACATAGCCGATCCAGATCCAAAGGTAAAGATGACCAAATTGACGATCGAGGAGTTTGAAAAGGAATGGACAGGGA
TTGTCATCGCCTTGGCCCCGACTCCAGCCTATCAACCGAGTAAAGAAAAGAAAAATGGGCTTTTAGATTTTGTCCCTCTT
TTGTTTAAACAGCGGCAATTGGTTCTGCATATTGTTCTTGCAACGTTATTGGTAACCCTCATCAATATTGTGGGTTCTTA
CTACTTACAATCGATTATTGATACCTATGTGCCTGATCAGATGAAGCAGACGCTGAGTGTGATTTCACTAGGGTTGATCG
TGGTTTACATCTTACAGCAAGTCCTAACCTATGCGCAAGATTACTTGCTTCTTGTTTTAGGTCAACGCTTGTCTATTGAT
GTCATTCTGTCCTATATTAAGCATGTTTTTCAGTTGCCTATGAGTTTCTTTGCGACTCGACGGACAGGAGAAGTGGTGTC
GCGGTTTACAGATGCCAACCGCATTATCGATGCTCTGGCTAGTACACTGCTCTCAATCTTTTTGGATCTGTCTATTGTTT
TGATTTTATCAGTAGTCCTGTTTAGCCAAAATGCTCACCTCTTTTTCTTGACCATTCTCTTGCTACCGATTTATGCGGTC
ATTATTTTTGCCTTTATGAAACCTTTTGAGCGCTTAAATAATGAAACCATGGAAGCCAATAGTGTCTTGTCTTCTTCCAT
CATCGAAGATATCAACGGGATTGAAACTATCAAGTCTCTTACCAGTGAGCGTAGTCGCTATCAAAAGATTGACTCAGAAT
TTGTGGACTATCTCAAGAAGTCCTTTGCCATGAGCAAGGCGGAGAGTCTACAAAAGGGGCTCAAGCACTTGGCCCAGTTG
ATTTTGAATGTCTTGGTCTTGTGGTTGGGAGCTCATTTGGTCATGAAGCAAGAATTGAGCTTGGGGCAGTTGATCACCTA
CAATACTCTCCTTGTTTATTTCACAGGCCCTTTAGAGAACTTGATTAACCTCCAAACCAAACTTCAAGCAGCCCGAGTGG
CCAATACCCGTCTGAATGAAGTCTATTTGATAGACTCTGAGTTCGCAGAGAAGAAGCCTCTTCAAAAGCGTGAGGCTCTC
GATGGTGATCTGGTTTTTGAGGGAGTAGACTACAAGTACGGTTTTGGGGCTAACGTTCTTACCGATATCAGTCTCACGAT
TAAAAAAGGGAGCAAGGTAAGTTTTGTTGGTATTTCAGGTTCTGGAAAAACCACGCTAGCAAAGATGATGGTGAATTTCT
ACCAACCCAATAAAGGGACGATTCGCCTAGGAGGAACGGATATCCAGCAAGTGGATAAAACTTTGCTCCGCCAGCAAATC
AATTATTTACCCCAGCAGCCCTATGTCTTTAATGGTACGATTTTAGAGAACCTGTTACTGGGAGCGCGGGAAGGAACTAG
TCAGGAAGATATCTTGCGCGCTGTTGAAATCGCAGGAATTCGAGAAGACATTGAGCGTATGCCCCTCAATTACCAAACAG
AATTGACTACGGATGGCATGGGAATCTCTGGTGGTCAACGGCAGCGGATTGCCTTGGCGCGTGCCTTATTAACGGATGCT
CCGATTCTGATTTTGGATGAAGCGACCAGCAGCCTGGATATCTTGACGGAGAAGAAAATTGTGGACCGCTTGATGGCCTT
AGACAAAACGATTATCTTTATCGCTCATCGGTTAACGATTGCAGAACGGTCTGAAAAAGTCTTCCTCATGGACCAAGGTC
GTCTGAAAGAAGAAGGAAGCCATGAAGAACTGCTGAAAAAGAATGGCTATTACAGCCATTTGGTTACTTGTTAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(171-438)

Peptidase C39 family (Peptidase_C39)

(6-142)

ABC transporter (ABC_tran)

(500-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

77.266

100

0.773
  comA Streptococcus mitis NCTC 12261

75.035

100

0.75
  comA Streptococcus pneumoniae Rx1

74.895

100

0.749
  comA Streptococcus pneumoniae D39

74.895

100

0.749
  comA Streptococcus pneumoniae R6

74.895

100

0.749
  comA Streptococcus mitis SK321

74.895

100

0.749
  comA Streptococcus pneumoniae TIGR4

74.477

100

0.745
  comA/nlmT Streptococcus mutans UA159

63.497

99.721

0.633

Multiple sequence alignment