Detailed information NTG0161012

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: APQ13_RS08645
• Genome accession: NZ_CP013237
• Coordinates: 1790220..1790654 (+)
• Length: 144 a.a.
• NCBI ID: WP_061046398.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain NG8 isolate Dental Plaque
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1785220..1795654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
APQ13_RS08615 (APQ13_08595)	-	1786842..1787225 (+)	384	WP_002264248.1	DUF1033 family protein	-
APQ13_RS08620 (APQ13_08600)	comYA	1787355..1788296 (+)	942	WP_002263435.1	competence type IV pilus ATPase ComGA	Machinery gene
APQ13_RS08625 (APQ13_08605)	comYB	1788232..1789263 (+)	1032	WP_255262721.1	competence type IV pilus assembly protein ComGB	Machinery gene
APQ13_RS08630 (APQ13_08610)	comYC	1789263..1789577 (+)	315	WP_002263437.1	competence type IV pilus major pilin ComGC	Machinery gene
APQ13_RS08635 (APQ13_08615)	comYD	1789564..1789968 (+)	405	WP_002264246.1	competence type IV pilus minor pilin ComGD	Machinery gene
APQ13_RS08640 (APQ13_08620)	comYE	1789940..1790233 (+)	294	WP_002263439.1	competence type IV pilus minor pilin ComGE	Machinery gene
APQ13_RS08645 (APQ13_08625)	comYF	1790220..1790654 (+)	435	WP_061046398.1	competence type IV pilus minor pilin ComGF	Machinery gene
APQ13_RS08650 (APQ13_08630)	comYG	1790632..1791021 (+)	390	WP_002263441.1	competence type IV pilus minor pilin ComGG	Machinery gene
APQ13_RS08655 (APQ13_08635)	comYH	1791076..1792029 (+)	954	WP_002263442.1	class I SAM-dependent methyltransferase	Machinery gene
APQ13_RS08660 (APQ13_08640)	-	1792088..1793287 (+)	1200	WP_002263443.1	acetate kinase	-
APQ13_RS08665 (APQ13_08645)	-	1793840..1794085 (+)	246	WP_002263444.1	helix-turn-helix transcriptional regulator	-
APQ13_RS08670 (APQ13_08650)	-	1794054..1794494 (+)	441	WP_002263445.1	hypothetical protein	-
APQ13_RS08675 (APQ13_08655)	-	1794547..1795209 (+)	663	WP_002266816.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16351.86 Da
• Isoelectric Point: 10.0840

>NTDB_id=161012 APQ13_RS08645 WP_061046398.1 1790220..1790654(+) (comYF) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MLKSKLKAFTLLECLLALLVIAGSVSVYNGLTKAISSNIHYLSKNQEDAWLLFCQQFRSELERTTLQKLDSNKLYVQKNN
QSLAFGKSKASDFRKTNSDGRGYQPMLTEIKAANFSQSGKIIKLDLTFKDGLERTFVYAFHEKN

Nucleotide

• Length: 435 bp

>NTDB_id=161012 APQ13_RS08645 WP_061046398.1 1790220..1790654(+) (comYF) [Streptococcus mutans strain NG8 isolate Dental Plaque]
TTGTTAAAAAGTAAATTGAAAGCTTTCACACTTTTAGAGTGTCTCCTTGCTTTGCTTGTCATTGCTGGTAGTGTATCTGT
TTATAATGGTCTAACTAAAGCTATTAGTAGTAATATTCATTACTTATCAAAAAATCAAGAAGATGCTTGGTTACTTTTTT
GTCAGCAATTTCGGTCTGAACTTGAAAGAACGACTTTGCAAAAATTGGATAGCAATAAGCTTTATGTTCAAAAAAATAAT
CAAAGTTTAGCCTTTGGTAAATCAAAAGCAAGTGATTTTAGAAAGACTAACAGTGATGGACGTGGTTATCAGCCTATGTT
GACGGAGATCAAAGCTGCTAATTTTAGTCAATCAGGAAAAATTATTAAATTAGACCTTACTTTCAAAGATGGTTTAGAGA
GGACTTTTGTTTATGCTTTTCATGAAAAAAATTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (36-133)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	99.306	100	0.993
comYF	Streptococcus mutans UA159	98.611	100	0.986
comGF	Lactococcus lactis subsp. cremoris KW2	43.262	97.917	0.424
comGF/cglF	Streptococcus pneumoniae Rx1	41.045	93.056	0.382
comGF/cglF	Streptococcus pneumoniae D39	41.045	93.056	0.382
comGF/cglF	Streptococcus pneumoniae R6	41.045	93.056	0.382
comGF/cglF	Streptococcus pneumoniae TIGR4	41.045	93.056	0.382
comGF/cglF	Streptococcus mitis NCTC 12261	39.552	93.056	0.368
comGF/cglF	Streptococcus mitis SK321	38.806	93.056	0.361