Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   APQ13_RS08640 Genome accession   NZ_CP013237
Coordinates   1789940..1790233 (+) Length   97 a.a.
NCBI ID   WP_002263439.1    Uniprot ID   -
Organism   Streptococcus mutans strain NG8 isolate Dental Plaque     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1784940..1795233
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APQ13_RS08615 (APQ13_08595) - 1786842..1787225 (+) 384 WP_002264248.1 DUF1033 family protein -
  APQ13_RS08620 (APQ13_08600) comYA 1787355..1788296 (+) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  APQ13_RS08625 (APQ13_08605) comYB 1788232..1789263 (+) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  APQ13_RS08630 (APQ13_08610) comYC 1789263..1789577 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  APQ13_RS08635 (APQ13_08615) comYD 1789564..1789968 (+) 405 WP_002264246.1 competence type IV pilus minor pilin ComGD Machinery gene
  APQ13_RS08640 (APQ13_08620) comYE 1789940..1790233 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  APQ13_RS08645 (APQ13_08625) comYF 1790220..1790654 (+) 435 WP_061046398.1 competence type IV pilus minor pilin ComGF Machinery gene
  APQ13_RS08650 (APQ13_08630) comYG 1790632..1791021 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  APQ13_RS08655 (APQ13_08635) comYH 1791076..1792029 (+) 954 WP_002263442.1 class I SAM-dependent methyltransferase Machinery gene
  APQ13_RS08660 (APQ13_08640) - 1792088..1793287 (+) 1200 WP_002263443.1 acetate kinase -
  APQ13_RS08665 (APQ13_08645) - 1793840..1794085 (+) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -
  APQ13_RS08670 (APQ13_08650) - 1794054..1794494 (+) 441 WP_002263445.1 hypothetical protein -
  APQ13_RS08675 (APQ13_08655) - 1794547..1795209 (+) 663 WP_002266816.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11001.91 Da        Isoelectric Point: 9.4908

>NTDB_id=161011 APQ13_RS08640 WP_002263439.1 1789940..1790233(+) (comYE) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MVSIKKQKVKAYILLESLVALGLFVTITTLILTQLSHYQERTAKNLQKQEILNLAIMALQTQQDHLSFNGVSVTVVKNQG
ETIVYHDHEEVINLVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=161011 APQ13_RS08640 WP_002263439.1 1789940..1790233(+) (comYE) [Streptococcus mutans strain NG8 isolate Dental Plaque]
GTGGTCAGTATAAAAAAACAGAAAGTTAAAGCTTATATTCTTCTAGAAAGTTTAGTTGCTTTGGGACTTTTCGTAACCAT
CACAACTTTAATTCTTACTCAGTTGAGTCATTATCAGGAAAGAACAGCTAAAAATTTACAAAAACAAGAAATATTGAATT
TAGCAATAATGGCTCTTCAAACTCAGCAAGATCATTTAAGCTTCAACGGCGTCAGTGTTACGGTTGTTAAAAATCAAGGG
GAAACTATAGTTTATCATGATCATGAGGAGGTTATCAATCTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

100

100

1
  comYE Streptococcus mutans UA159

100

100

1
  comGE/cglE Streptococcus pneumoniae Rx1

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae D39

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae R6

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae TIGR4

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis NCTC 12261

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis SK321

44.444

92.784

0.412

Multiple sequence alignment