Detailed information NTG0160732

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: HSISS4_RS09745
• Genome accession: NZ_CP013216
• Coordinates: 2098786..2100021 (+)
• Length: 411 a.a.
• NCBI ID: WP_013991347.1
• Uniprot ID: A0AB37CMH1
• Organism: Streptococcus salivarius strain HSISS4
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2093786..2105021

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HSISS4_RS09715 (HSISS4_01899)	-	2094258..2096852 (+)	2595	WP_021144766.1	YfhO family protein	-
HSISS4_RS09735 (HSISS4_01900)	-	2097402..2098085 (-)	684	WP_059749256.1	YoaK family protein	-
HSISS4_RS09740 (HSISS4_01901)	rlmH	2098101..2098580 (-)	480	WP_021144768.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
HSISS4_RS09745 (HSISS4_01902)	htrA	2098786..2100021 (+)	1236	WP_013991347.1	S1C family serine protease	Regulator
HSISS4_RS09750 (HSISS4_01903)	spo0J	2100087..2100854 (+)	768	WP_014635206.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42915.09 Da
• Isoelectric Point: 4.6266

>NTDB_id=160732 HSISS4_RS09745 WP_013991347.1 2098786..2100021(+) (htrA) [Streptococcus salivarius strain HSISS4]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSSQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKAGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide

• Length: 1236 bp

>NTDB_id=160732 HSISS4_RS09745 WP_013991347.1 2098786..2100021(+) (htrA) [Streptococcus salivarius strain HSISS4]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTACTAGGTGGTTTACTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ATAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTACCAAGAAGGGTCA
TCATCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGATTCTAGTCAAGACAAATCAAA
AGATTCTGATGGGTTGCAAGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGGAAAGAGGCCTACATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTTGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCGGAATTTGCAGACTC
AAACTCTCTCACAGTCGGCGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATATGCCAACTCAGTAACAGAGG
GTATCGTTTCTAGCCTTAGCCGTACTGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATCCAAACA
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCAGCAGTCGCTGGTAGCGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAAA
TCATCAATCAATTGGAAAAAGACGGTAAAGTTACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAACAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAAGCTGGAGTTGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (7-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.389	98.783	0.567
htrA	Streptococcus pneumoniae Rx1	54.279	99.513	0.54
htrA	Streptococcus pneumoniae R6	54.279	99.513	0.54
htrA	Streptococcus pneumoniae TIGR4	54.279	99.513	0.54
htrA	Streptococcus pneumoniae D39	54.279	99.513	0.54
htrA	Streptococcus mitis NCTC 12261	54.279	99.513	0.54