Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   HSISS4_RS04380 Genome accession   NZ_CP013216
Coordinates   906906..907613 (+) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus salivarius strain HSISS4     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 901906..912613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSISS4_RS04355 (HSISS4_00831) - 902329..903578 (+) 1250 Protein_829 ISL3 family transposase -
  HSISS4_RS04360 (HSISS4_00832) - 903633..904283 (-) 651 WP_059749145.1 amino acid ABC transporter permease -
  HSISS4_RS04365 (HSISS4_00833) - 904295..904993 (-) 699 WP_014633207.1 amino acid ABC transporter permease -
  HSISS4_RS04370 (HSISS4_00834) - 905011..905844 (-) 834 WP_021144260.1 transporter substrate-binding domain-containing protein -
  HSISS4_RS04375 (HSISS4_00835) - 905854..906621 (-) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  HSISS4_RS04380 (HSISS4_00836) vicR 906906..907613 (+) 708 WP_002884978.1 response regulator YycF Regulator
  HSISS4_RS04385 (HSISS4_00837) vicK 907606..908946 (+) 1341 WP_002885062.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HSISS4_RS04390 (HSISS4_00838) vicX 908952..909764 (+) 813 WP_013990680.1 MBL fold metallo-hydrolase Regulator
  HSISS4_RS04395 (HSISS4_00839) - 909823..910182 (+) 360 WP_002885010.1 YbaN family protein -
  HSISS4_RS04400 (HSISS4_00840) - 910234..911448 (-) 1215 WP_021144256.1 aminoacyltransferase -
  HSISS4_RS04405 (HSISS4_00841) yidA 911450..912259 (-) 810 WP_002885000.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=160705 HSISS4_RS04380 WP_002884978.1 906906..907613(+) (vicR) [Streptococcus salivarius strain HSISS4]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=160705 HSISS4_RS04380 WP_002884978.1 906906..907613(+) (vicR) [Streptococcus salivarius strain HSISS4]
ATGAAAAAAATTCTAGTAGTTGATGATGAAAGACCAATCTCGGATATCATCAAGTTTAATCTGACTAAAGAGGGTTATGA
AGTTGTTACGGCTTTTGATGGTCGGGAAGCTTTAGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTAGACTTGA
TGTTGCCTGAACTAGATGGCTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCAATTATCATGCTTTCCGCT
AAGGATAGCGAGTTCGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACAAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTTGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATTTGGCAACTCATATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387

Multiple sequence alignment