Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   HSISS4_RS04385 Genome accession   NZ_CP013216
Coordinates   907606..908946 (+) Length   446 a.a.
NCBI ID   WP_002885062.1    Uniprot ID   A0A0F3HCD0
Organism   Streptococcus salivarius strain HSISS4     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 902606..913946
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSISS4_RS04360 (HSISS4_00832) - 903633..904283 (-) 651 WP_059749145.1 amino acid ABC transporter permease -
  HSISS4_RS04365 (HSISS4_00833) - 904295..904993 (-) 699 WP_014633207.1 amino acid ABC transporter permease -
  HSISS4_RS04370 (HSISS4_00834) - 905011..905844 (-) 834 WP_021144260.1 transporter substrate-binding domain-containing protein -
  HSISS4_RS04375 (HSISS4_00835) - 905854..906621 (-) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  HSISS4_RS04380 (HSISS4_00836) vicR 906906..907613 (+) 708 WP_002884978.1 response regulator YycF Regulator
  HSISS4_RS04385 (HSISS4_00837) vicK 907606..908946 (+) 1341 WP_002885062.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HSISS4_RS04390 (HSISS4_00838) vicX 908952..909764 (+) 813 WP_013990680.1 MBL fold metallo-hydrolase Regulator
  HSISS4_RS04395 (HSISS4_00839) - 909823..910182 (+) 360 WP_002885010.1 YbaN family protein -
  HSISS4_RS04400 (HSISS4_00840) - 910234..911448 (-) 1215 WP_021144256.1 aminoacyltransferase -
  HSISS4_RS04405 (HSISS4_00841) yidA 911450..912259 (-) 810 WP_002885000.1 sugar-phosphatase -
  HSISS4_RS04410 (HSISS4_00842) - 912437..913303 (+) 867 WP_021144255.1 GNAT family N-acetyltransferase -
  HSISS4_RS04415 (HSISS4_00843) - 913386..913772 (+) 387 WP_021144254.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50945.21 Da        Isoelectric Point: 5.1606

>NTDB_id=160706 HSISS4_RS04385 WP_002885062.1 907606..908946(+) (vicK) [Streptococcus salivarius strain HSISS4]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDYETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=160706 HSISS4_RS04385 WP_002885062.1 907606..908946(+) (vicK) [Streptococcus salivarius strain HSISS4]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTTTCTTACATGAGTGATGGGGTTAT
TGCGACAAATCGTCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTATGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAGTGAATTGCTGTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAATGATGAGTTTGTGACCTTACGTGTTAACTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCCGTTCTTCACGATGCCACTGAGCAGGAAAAAGAAGAGCGGGAACGCCGACTCTTCGTCTCAA
ACGTTAGTCATGAGTTGCGCACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGTGCTCTCGACGAA
GAGATTGCTCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
ATCACGTATTGACAATAAGAGTACCCAACTTGACGTTGAGATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAGAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGAGATTATCCGGTAAACTCAATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTTGTGGATAATATTCTTAATAATGCTATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCGTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCCCAAGGTGGAACTGGTCTA
GGCTTGTCTATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F3HCD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.825

0.684
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657

Multiple sequence alignment