Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   HSISS4_RS01290 Genome accession   NZ_CP013216
Coordinates   249219..251315 (+) Length   698 a.a.
NCBI ID   WP_021143547.1    Uniprot ID   -
Organism   Streptococcus salivarius strain HSISS4     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 244219..256315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSISS4_RS01265 (HSISS4_00213) trkA 244310..245659 (-) 1350 WP_021143542.1 Trk system potassium transporter TrkA -
  HSISS4_RS01270 (HSISS4_00214) - 245937..246446 (+) 510 WP_021143543.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  HSISS4_RS01275 (HSISS4_00215) - 246757..247314 (+) 558 WP_021143544.1 ECF transporter S component -
  HSISS4_RS01280 (HSISS4_00216) - 247317..247967 (+) 651 WP_002889918.1 phosphatase PAP2 family protein -
  HSISS4_RS01285 (HSISS4_00217) comR 248145..249044 (+) 900 WP_021143546.1 helix-turn-helix transcriptional regulator Regulator
  - comS 249132..249206 (+) 75 - - Regulator
  HSISS4_RS01290 (HSISS4_00218) comA 249219..251315 (+) 2097 WP_021143547.1 peptide cleavage/export ABC transporter Regulator
  HSISS4_RS01295 (HSISS4_00219) - 251426..251758 (+) 333 WP_002886546.1 DUF805 domain-containing protein -
  HSISS4_RS01300 (HSISS4_00220) - 251809..253200 (-) 1392 WP_021143548.1 DUF4153 domain-containing protein -
  HSISS4_RS01305 (HSISS4_00221) - 253608..254123 (+) 516 WP_002886548.1 AmiS/UreI family transporter -
  HSISS4_RS01310 (HSISS4_00222) - 254148..254450 (+) 303 WP_002886558.1 urease subunit gamma -
  HSISS4_RS01315 (HSISS4_00223) - 254462..254773 (+) 312 WP_002886559.1 urease subunit beta -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78552.62 Da        Isoelectric Point: 9.4827

>NTDB_id=160690 HSISS4_RS01290 WP_021143547.1 249219..251315(+) (comA) [Streptococcus salivarius strain HSISS4]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQKKLSY
PFIVHVVKEGGLQHYYTVFGQIKGQLIIGDPDPSKKVIKIPLEEFAKEWTGVSLFFVPGETYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQAIIDRLIPQGAYNLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALIVQNQSLFLMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYREIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAF
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDTISHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKKLIKVCQQADILEDIQRMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSANFNPFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=160690 HSISS4_RS01290 WP_021143547.1 249219..251315(+) (comA) [Streptococcus salivarius strain HSISS4]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGAGAGTTGGCTCAGACTTCTCGTGAAGGTACTTCTGCGCTTGGTTTGGTGG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAAAAAAACTATCTTAT
CCTTTTATTGTACATGTGGTTAAAGAAGGTGGGCTGCAACATTATTATACGGTGTTTGGTCAAATTAAGGGGCAGCTTAT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATACCCTTAGAGGAATTTGCCAAAGAGTGGACGGGAGTTTCTC
TCTTTTTTGTTCCAGGAGAAACCTACACTAAATACAAAGAAGATGTACCTGGACTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTGCTGAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAAGCTATTATCGACCGCTTGATTCCTCAGGGGGCCTATAATCTTCTGACCATGATTTCGCTAGGCTTATGTATCTCTT
ATCTTGCTCAACAAGTTTTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGTAATTACCTGTCCATTGCTGTCATT
CTTCCTTATATCAAGCATGTCCTTTCCTTGCCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACGTCACGTTT
TGGAGATGCCAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTGTACAAAATCAGTCACTTTTTTTGATGACTCTCACGGTAGTTCCTCTTTATGTTTTAATCATT
CTGGCATTCTATAAGCTTTTTGAAAAAGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGTATTGAAACCTTAAAATCCTTGAGGGTTGAGGAAAGACGCTATCGGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCCTTGTCTAAGGCCAAGTGGCAATTAACGCAGGATGGGTTAAAGACAGGGGTTCAGTTAGTTTCT
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGTTATGGAAGGGCAACTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGTTGAATTATTTTACAACTCCTTTAATTAATATCATCAATCTCCAATCTAAAATTCAGCAAGCCAAAGTCGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTAGACAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCTTTTAAACAACTTGCTTTT
AAAGGAGTCAGTCACCGTTTTAGTTATCAGCAAGAGACTCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGAAAAACGACCTTAGCTAAAATGTTGTCAGGTTATTATACGAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATACCATTAGCCATGCGGAGTTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACGGGGACGATTTTAGAGAATCTTCTATTAGGATTTGAAGGAGAAGTTGACGAGAAAAAGCTTATTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAGAATGCCACTAGGCTTTCAGACCCAAGTATCTGAAGACGGTGGTTTGTCTG
GCGGTCAAAAACAAAGATTAGCTATAGCAAGGGCTCTATTGTCCAAACAACCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTACGTCAACATGTCAGTCGTGTAGTGACCATGGTGAGTGGCCAGATTGAGTCAGACAGTGCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter transmembrane region (ABC_membrane)

(167-436)

ABC transporter (ABC_tran)

(494-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

53.69

98.997

0.532
  comA Streptococcus gordonii str. Challis substr. CH1

52.874

99.713

0.527
  comA Streptococcus mitis NCTC 12261

53.256

98.997

0.527
  comA Streptococcus pneumoniae Rx1

53.111

98.997

0.526
  comA Streptococcus pneumoniae D39

53.111

98.997

0.526
  comA Streptococcus pneumoniae R6

53.111

98.997

0.526
  comA Streptococcus pneumoniae TIGR4

52.967

98.997

0.524
  comA/nlmT Streptococcus mutans UA159

50.58

98.854

0.5

Multiple sequence alignment