Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SanJ4206_RS03540 Genome accession   NZ_CP012719
Coordinates   724136..724837 (+) Length   233 a.a.
NCBI ID   WP_003027677.1    Uniprot ID   A0AAI9NI07
Organism   Streptococcus anginosus strain J4206     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 719136..729837
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4206_RS03520 (SanJ4206_0662) ccpA 719986..720990 (+) 1005 WP_003027685.1 catabolite control protein A Regulator
  SanJ4206_RS03525 (SanJ4206_0663) - 721170..722168 (+) 999 WP_022525098.1 glycosyltransferase family 4 protein -
  SanJ4206_RS03530 (SanJ4206_0664) - 722170..723483 (+) 1314 WP_022525097.1 glycosyltransferase family 4 protein -
  SanJ4206_RS03535 (SanJ4206_0665) - 723510..723851 (+) 342 WP_003027678.1 hypothetical protein -
  SanJ4206_RS03540 (SanJ4206_0666) micA 724136..724837 (+) 702 WP_003027677.1 response regulator YycF Regulator
  SanJ4206_RS03545 (SanJ4206_0667) micB 724830..726182 (+) 1353 WP_003027674.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SanJ4206_RS03550 (SanJ4206_0668) vicX 726185..726988 (+) 804 WP_003027672.1 MBL fold metallo-hydrolase Regulator
  SanJ4206_RS03555 (SanJ4206_0669) - 726997..727355 (+) 359 Protein_663 YbaN family protein -
  SanJ4206_RS03560 (SanJ4206_0670) rnc 727729..728427 (+) 699 WP_003027666.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26972.97 Da        Isoelectric Point: 4.6957

>NTDB_id=156777 SanJ4206_RS03540 WP_003027677.1 724136..724837(+) (micA) [Streptococcus anginosus strain J4206]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPEMDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAEPKEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=156777 SanJ4206_RS03540 WP_003027677.1 724136..724837(+) (micA) [Streptococcus anginosus strain J4206]
ATGAAAAAAATATTAGTTGTAGATGATGAAAAACCAATCTCAGATATCATAAAATTTAACATGGTAAAAGAAGGTTATGA
GGTAGTGACAGCCTTCGACGGTCGCGAAGCGTTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCCGAAATGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGTAATGTGCCAATCATCGTTCTTTCTGCC
AAAGACAGTGAATTTGACAAAGTTATTGGTCTTGAGATTGGTGCAGATGACTATATGACAAAGCCTTTCTCTAATCGTGA
ATTGCAGGCGCGTGTCAAAGCCATTTTGCGGCGGACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGAACCAAAAG
AAATTGTGATTGGAGATCTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTAGATTTAACACAC
CGTGAGTTTGAATTGCTCCACCATTTGGCAACGCATATCGGGCAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTACGGACGGTCGATGTGACAATTCGCCGTTTGAGAGAAAAGATTGAGGATATTCCTA
GCCGACCAGAGTATATTTTAACACGGCGCGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

44.978

98.283

0.442
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361

Multiple sequence alignment