Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   RN80_RS01720 Genome accession   NZ_CP012646
Coordinates   323071..324420 (-) Length   449 a.a.
NCBI ID   WP_060627292.1    Uniprot ID   -
Organism   Streptococcus mitis strain KCOM 1350 (= ChDC B183)     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 318071..329420
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RN80_RS01710 (RN80_01720) - 318267..321992 (-) 3726 WP_060627290.1 phosphoribosylformylglycinamidine synthase -
  RN80_RS10195 - 322048..322191 (-) 144 WP_080998552.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  RN80_RS01715 (RN80_01725) purC 322193..322900 (-) 708 WP_060627291.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  RN80_RS01720 (RN80_01730) comB 323071..324420 (-) 1350 WP_060627292.1 competence pheromone export protein ComB Regulator
  RN80_RS01725 (RN80_01735) comA 324433..326586 (-) 2154 WP_060627293.1 peptide cleavage/export ABC transporter ComA Regulator
  RN80_RS01735 (RN80_01745) - 327172..327351 (-) 180 WP_060627294.1 hypothetical protein -
  RN80_RS10065 - 327432..327647 (-) 216 WP_080550793.1 bacteriocin immunity protein -
  RN80_RS01740 (RN80_01750) - 327651..327806 (-) 156 WP_000357248.1 smi_0061 family bacteriocin-like peptide -
  RN80_RS01750 (RN80_01760) - 328020..328217 (-) 198 WP_000180825.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  RN80_RS01755 (RN80_01765) - 328531..329262 (-) 732 WP_060627295.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49952.00 Da        Isoelectric Point: 5.2600

>NTDB_id=155983 RN80_RS01720 WP_060627292.1 323071..324420(-) (comB) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MKPEFLESAEFYNRRYHNFSSRVIVPMSLLLVFLLGFAIFAEKEMSLSTRATIEPSRILANIQSTSNNRILVNHLEENKL
VKKGELLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGTDYFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQVEIGNLISQTEAKIRDYQTAKSAIETGASLASQNLAYSLYQSYKSQSEENPQAKFQAVAQVEAQLS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLDQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSTMVAEGTLLAQLYPSLEKEGKAKLTAYLSSKDVARIKVGDSVCYTTTHDAKNQIFLDSTITSIDATATKTEK
GNFFKIEVETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=155983 RN80_RS01720 WP_060627292.1 323071..324420(-) (comB) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTGTCCCCAT
GTCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAATATTTGCAGAGAAGGAGATGAGTTTGTCTACTAGAGCTACTATCG
AACCTAGCCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGAGCTTCTTGTTCAATATCAGGAAGGGGCAGAGGGTGTCCAAGCGGAGTCTTATGCCAGTCAGTTGGA
CATGCTCAAGGATCAAAAAAAGCAATTGGAGTATTTGCAAAAGAGCCTGCAAGAAGGGACGGATTACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAC
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGTCGAAATCGGCAACCTCATCAGCCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTCT
ACCAGTCCTACAAGTCTCAGAGTGAGGAAAATCCCCAAGCTAAATTCCAGGCAGTTGCGCAAGTTGAAGCACAGCTTTCT
CAGTTAGAATCCAGTCTTGCTACTTACCGTGTCCAGTATGCGGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGCTTAAG
CAGTCAATTGGAGTCCCTTAAATCCCAACACTTAGCAAAGGTTGGTCAGGAATTGACCCTTCTAGACCAGAAAATCTTGG
AGGCAGAGTCGGGTAAGAAGGTTCAGGGGAATCTTCTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTTCTTCAT
CTTAATCCTGAGACCAGTGATTCTACCATGGTAGCAGAGGGGACTCTACTAGCCCAACTCTATCCGTCCTTGGAAAAAGA
AGGGAAAGCCAAACTAACAGCTTATCTTAGTTCAAAGGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTTGCTATACTA
CGACTCATGATGCCAAGAATCAAATTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACCAAGACTGAAAAA
GGGAATTTCTTTAAAATCGAGGTGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTCGATATGGGGTGGAAGGTCG
TCTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

95.991

100

0.96
  comB Streptococcus pneumoniae Rx1

94.655

100

0.947
  comB Streptococcus pneumoniae D39

94.655

100

0.947
  comB Streptococcus pneumoniae R6

94.655

100

0.947
  comB Streptococcus pneumoniae TIGR4

94.432

100

0.944
  comB Streptococcus mitis NCTC 12261

93.987

100

0.94
  comB Streptococcus gordonii str. Challis substr. CH1

55.333

100

0.555

Multiple sequence alignment